Zobrazeno 1 - 10
of 12
pro vyhledávání: '"William L. Matier"'
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 13(4-5)
A novel HPLC method for determination of EDTA in a cataract inhibiting ophthalmic drug product has been developed. In this method EDTA was converted to Cu(II)EDTA complex, using Cu + 2 containing mobile phase, after injection into the chromatographic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5107ebca5c302e721f20f6cedd38e907
https://pubmed.ncbi.nlm.nih.gov/9696572
https://pubmed.ncbi.nlm.nih.gov/9696572
Publikováno v:
The Journal of Organic Chemistry. 48:5369-5373
Etude du mecanisme de la reaction de Strecker conduisant a des α-[phenyl-1 ethylamino] benzeneacetonitriles par reaction de derives du benzaldehyde avec NaCN et la phenyl-1 ethylamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f4cdb8cf5f68e97ffcf25dadeb749b
https://doi.org/10.1021/jo00174a046
https://doi.org/10.1021/jo00174a046
Publikováno v:
Journal of Medicinal Chemistry. 27:1347-1350
Thirty amides patterned after the antiarrhythmic drug changrolin were synthesized and their antiarrhythmic and parasympatholytic activities were assessed. There was no correlation between antiarrhythmic and parasympatholytic activities. Several of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93754f251edd542c7a0bfa210aa09ca2
https://doi.org/10.1021/jm00376a022
https://doi.org/10.1021/jm00376a022
Publikováno v:
Journal of Medicinal Chemistry. 26:1109-1112
Various ethylenediamine derivatives have been incorporated into the nitrogen substituent of certain short-acting (aryloxy)propanolamine systems that contain esters on their aryl functions. Although several of these compounds showed durations of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44aad30561c3cf2aed61aec8d96532d
https://doi.org/10.1021/jm00362a004
https://doi.org/10.1021/jm00362a004
Publikováno v:
The Journal of Clinical Pharmacology. 26:44-47
The urinary excretion patterns of esmolol, a short-acting beta blocker, and its major metabolite were investigated in eight healthy men after intravenous infusion of 50, 100, 200, and 300 micrograms/kg/min of esmolol for six hours and 150 micrograms/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e074e23808ee4ef436a6a528ec5e1831
https://doi.org/10.1002/j.1552-4604.1986.tb02901.x
https://doi.org/10.1002/j.1552-4604.1986.tb02901.x
Autor:
Prasad Turlapaty, William L. Matier, Debra Drissel, Ramanuj Achari, Atul Laddu, Valerie Bell, James D. Hulse
Publikováno v:
The Journal of Clinical Pharmacology. 27:60-64
The pharmacokinetics and pharmacodynamics of flestolol, a new short-acting, beta-adrenergic receptor antagonist, were examined in nine healthy subjects after a constant intravenous infusion of 5 μg/kg/min for 72 hours. Flestolol blood levels were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28bbd2119febe73b371dad023a1bdcd
https://doi.org/10.1177/009127008702700109
https://doi.org/10.1177/009127008702700109
Autor:
David T. Lowenthal, Prasad Turlapaty, William L. Matier, Atul Laddu, R. Stephen Porter, Ramanuj Achari
Publikováno v:
The Journal of Clinical Pharmacology. 27:561-566
An open-label baseline-controlled study was conducted in 11 healthy male subjects to study the possible interaction between the cardioselective, short-acting beta blocker esmolol and digoxin when administered concurrently under steady-state condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08aae9b46b3b6df846b39a238a3e2f69
https://doi.org/10.1002/j.1552-4604.1987.tb03067.x
https://doi.org/10.1002/j.1552-4604.1987.tb03067.x
Autor:
John P. O'Donnell, C. Y. Sum, Robert J. Borgman, William L. Matier, K. X. Mai, Cynthia Barcelon-Yang, William G. Anderson, Herman F. Stampfli, R. J. Lee, Kam Sheung Tsam, Richard J. Gorczynski
Publikováno v:
Chemischer Informationsdienst. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a000f6fa6926db9d635ba2ca7d028c
https://doi.org/10.1002/chin.198503178
https://doi.org/10.1002/chin.198503178
Autor:
Cynthia Barcelon-Yang, Lawrence A. Black, Check Y. Quon, David M. Stout, Herman F. Stampfli, William L. Matier, Barry S. Brown
Publikováno v:
Journal of medicinal chemistry. 32(8)
In an effort to find a replacement for the iv antiarrhythmic drug lidocaine having reduced systemic and central nervous system effects, activity against supraventricular as well as ventricular arrhythmias, and a biological half-life of less than 15 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f096c4f0b9f59671a79d28704ac72b2
https://pubmed.ncbi.nlm.nih.gov/2754714
https://pubmed.ncbi.nlm.nih.gov/2754714
Publikováno v:
Journal of medicinal chemistry. 26(6)
Twenty-four structural derivatives of the antiarrhythmic drug changrolin were synthesized and tested for antiarrhythmic and parasympatholytic activities. It was found that while the bis(pyrrolidinylmethyl)phenol pattern of changrolin appeared to be o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01e08536ad6f7105559c38cdf439389
https://pubmed.ncbi.nlm.nih.gov/6854583
https://pubmed.ncbi.nlm.nih.gov/6854583