Zobrazeno 1 - 10
of 66
pro vyhledávání: '"William L. Chick"'
Publikováno v:
Cell Transplantation, Vol 3 (1994)
Dithizone (DTZ) is a recognized diabetogenic agent in vivo, and a supravital stain commonly used for identification of islets to be used for transplantation. In the present studies, we compared DTZ staining of freshly isolated and cultured canine, bo
Externí odkaz:
https://doaj.org/article/d173a02f5cee44a4a1086a51c864f30f
Autor:
William L. Chick, Robert Lanza
Publikováno v:
Annals of the New York Academy of Sciences. 831:323-331
The currently limited supply of human pancreatic glands, and the fact that multiple glands may be required to isolate sufficient numbers of islets to treat a single patient, indicate that techniques must be further developed and refined for xenograft
Autor:
William L. Chick, Robert Lanza
Publikováno v:
Surgery. 121:1-9
fue body by a selectively permeable membrane.1-3 The membrane allows fue free exchange of nutrients, oxygen, and biotherapeutic substances between fue blood or plasma and fue encapsulated cells, whereas high molecular weight substances such as immuno
Publikováno v:
Nature Biotechnology. 14:1107-1111
The potential therapeutic applications of encapsulated cells are enormous. In the US alone, it has been estimated that nearly half-a-trillion dollars are spent each year to care for patients who suffer tissue loss or dysfunction. Over 6 million patie
Autor:
William L. Chick, Robert Lanza
Publikováno v:
Transplantation Reviews. 9:217-230
Publikováno v:
Cell Transplantation, Vol 3 (1994)
Dithizone (DTZ) is a recognized diabetogenic agent in vivo, and a supravital stain commonly used for identification of islets to be used for transplantation. In the present studies, we compared DTZ staining of freshly isolated and cultured canine, bo
Publikováno v:
Transplantation. 56:1067-1071
Long-term function of canine, bovine, and porcine islet xenografts implanted in streptozotocin-induced diabetic rats has been achieved by islet encapsulation within permselective acrylic membrane chambers. Intraperitoneal implants of 1 x 10(4) (n = 1
Publikováno v:
ASAIO Journal. 39:M247-M251
Oxygen tension is of potential importance in hybrid diffusion chambers, where both islet density and the site chosen for implantation can significantly affect the pO2 within the chambers. To investigate this, isolated islets were incubated at oxygen
Autor:
TAKASHI MAKI, J. PETER A. LODGE, MAURO CARRETTA, HIROKI OHZATO, KERMIT M. BORLAND, SUSAN J. SULLIVAN, JAMES STARUK, THOMAS E. MULLER, BARRY A. SOLOMON, WILLIAM L. CHICK, ANTHONY P. MONACO
Publikováno v:
Transplantation. 55:713-717
We report the successful application of a hybrid artificial pancreas device for the treatment of severe diabetes mellitus induced by total pancreatectomy in two dogs. Control of the blood sugar was achieved for more than 1 year in these two animals w