Zobrazeno 1 - 10
of 206
pro vyhledávání: '"William L Lowe"'
Autor:
Maggie C Y Ng, Daniel Shriner, Brian H Chen, Jiang Li, Wei-Min Chen, Xiuqing Guo, Jiankang Liu, Suzette J Bielinski, Lisa R Yanek, Michael A Nalls, Mary E Comeau, Laura J Rasmussen-Torvik, Richard A Jensen, Daniel S Evans, Yan V Sun, Ping An, Sanjay R Patel, Yingchang Lu, Jirong Long, Loren L Armstrong, Lynne Wagenknecht, Lingyao Yang, Beverly M Snively, Nicholette D Palmer, Poorva Mudgal, Carl D Langefeld, Keith L Keene, Barry I Freedman, Josyf C Mychaleckyj, Uma Nayak, Leslie J Raffel, Mark O Goodarzi, Y-D Ida Chen, Herman A Taylor, Adolfo Correa, Mario Sims, David Couper, James S Pankow, Eric Boerwinkle, Adebowale Adeyemo, Ayo Doumatey, Guanjie Chen, Rasika A Mathias, Dhananjay Vaidya, Andrew B Singleton, Alan B Zonderman, Robert P Igo, John R Sedor, FIND Consortium, Edmond K Kabagambe, David S Siscovick, Barbara McKnight, Kenneth Rice, Yongmei Liu, Wen-Chi Hsueh, Wei Zhao, Lawrence F Bielak, Aldi Kraja, Michael A Province, Erwin P Bottinger, Omri Gottesman, Qiuyin Cai, Wei Zheng, William J Blot, William L Lowe, Jennifer A Pacheco, Dana C Crawford, eMERGE Consortium, DIAGRAM Consortium, Elin Grundberg, MuTHER Consortium, Stephen S Rich, M Geoffrey Hayes, Xiao-Ou Shu, Ruth J F Loos, Ingrid B Borecki, Patricia A Peyser, Steven R Cummings, Bruce M Psaty, Myriam Fornage, Sudha K Iyengar, Michele K Evans, Diane M Becker, W H Linda Kao, James G Wilson, Jerome I Rotter, Michèle M Sale, Simin Liu, Charles N Rotimi, Donald W Bowden, MEta-analysis of type 2 DIabetes in African Americans Consortium
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004517 (2014)
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studi
Externí odkaz:
https://doaj.org/article/56bb7be103094e20a1ebafe269f259c2
Autor:
Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Higher maternal pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and perinatal outcomes. However, whether these associations are causal remains unclear. Methods We explored the relation of maternal pre-/ear
Externí odkaz:
https://doaj.org/article/0a4789dc4d5f4384bda3a38300dc1bb0
Autor:
Ellen C. Francis, Camille E. Powe, William L. Lowe, Sara L. White, Denise M. Scholtens, Jiaxi Yang, Yeyi Zhu, Cuilin Zhang, Marie-France Hivert, Soo Heon Kwak, Arianne Sweeting, ADA/EASD PMDI
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-17 (2023)
Abstract Background Perinatal outcomes vary for women with gestational diabetes mellitus (GDM). The precise factors beyond glycemic status that may refine GDM diagnosis remain unclear. We conducted a systematic review and meta-analysis of potential p
Externí odkaz:
https://doaj.org/article/8a8c577fad694c93bf5f946b62e7465f
Autor:
Margrit Urbanek, M Geoffrey Hayes, Hoon Lee, Rachel M Freathy, Lynn P Lowe, Christine Ackerman, Nadereh Jafari, Alan R Dyer, Nancy J Cox, David B Dunger, Andrew T Hattersley, Boyd E Metzger, William L Lowe
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32958 (2012)
Since mediators of inflammation are associated with insulin resistance, and the risk of developing diabetes mellitus and gestational diabetes, we hypothesized that genetic variation in members of the inflammatory gene pathway impact glucose levels an
Externí odkaz:
https://doaj.org/article/312ea9c9afbd45fe926fb61a24a6f4fc
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9105 (2010)
BACKGROUND: Identification of receptor mediated signaling pathways in embryonic stem (ES) cells is needed to facilitate strategies for cell replacement using ES cells. One large receptor family, largely uninvestigated in ES cells, is G protein couple
Externí odkaz:
https://doaj.org/article/f8f43e9c3da94b40b48884426b7df8fb
Autor:
Kwun Kiu Wong, Feifei Cheng, Cadmon K. P. Lim, Claudia H. T. Tam, Greg Tutino, Lai Yuk Yuen, Chi Chiu Wang, Yong Hou, Michael H. M. Chan, Chung Shun Ho, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Boyd E. Metzger, William L. Lowe, Wing Hung Tam, Ronald C. W. Ma
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Leukocyte telomere length (LTL) is suggested to be a biomarker of biological age and reported to be associated with metabolic diseases such as type 2 diabetes. Glucose metabolic traits including glucose and insulin levels have bee
Externí odkaz:
https://doaj.org/article/b98d477d5d314a0f942fadeea67d4b18
Autor:
Monica E. Bianco, My H. Vu, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Denise M. Scholtens, Jami Josefson, William L. Lowe
Publikováno v:
Metabolites, Vol 13, Iss 6, p 749 (2023)
Maternal metabolites influence the size of newborns independently of maternal body mass index (BMI) and glycemia, highlighting the importance of maternal metabolism on offspring outcomes. This study examined associations of maternal metabolites durin
Externí odkaz:
https://doaj.org/article/76c1c5db59fd4e11bde4232cbc0f9be2
Autor:
Brooke Gleason, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Denise M. Scholtens, William L. Lowe
Publikováno v:
Metabolites, Vol 13, Iss 4, p 505 (2023)
The in utero environment is important for newborn size at birth, which is associated with childhood adiposity. We examined associations between maternal metabolite levels and newborn birthweight, sum of skinfolds (SSF), and cord C-peptide in a multin
Externí odkaz:
https://doaj.org/article/0da6bab1d495420a8195ba97577d59ac
Autor:
William L. Lowe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6047 (2023)
Gestational diabetes (GDM) is one of the most common complications of pregnancy, affecting as many as one in six pregnancies. It is associated with both short- and long-term adverse outcomes for the mother and fetus and has important implications for
Externí odkaz:
https://doaj.org/article/22eeb835b31548189bd964b51b73048b
Autor:
Ellen C. Francis, Camille E. Powe, William L. Lowe, Sara L. White, Denise M. Scholtens, Cuilin Zhang, Yeyi Zhu, Marie-France Hivert, Soo Heon Kwak, Arianne Sweeting
BackgroundAmong people with gestational diabetes mellitus (GDM), there is inter-individual variability in clinical outcomes that appears to be related to factors beyond glycemia. However, the precise factors (information on the unique pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c2e6413a7eb47c078a2ff6066addcc
https://doi.org/10.1101/2023.04.19.23288627
https://doi.org/10.1101/2023.04.19.23288627