Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William Koltun"'
Autor:
Fernand, Labrie, David F, Archer, William, Koltun, Andrée, Vachon, Douglas, Young, Louise, Frenette, David, Portman, Marlene, Montesino, Isabelle, Côté, Julie, Parent, Lyne, Lavoie, Adam, Beauregard, Céline, Martel, Mario, Vaillancourt, John, Balser, Érick, Moyneur
Publikováno v:
Menopause. 25:1339-1353
The aim of this study is to confirm the local beneficial effects of intravaginal dehydroepiandrosterone (DHEA, Prasterone) on moderate to severe dyspareunia or pain at sexual activity, the most frequent symptom of vulvovaginal atrophy due to menopaus
Autor:
Kunwar Shailubhai, Blas Prieto, Marianela De La Portilla, Philip B. Miner, Gregory J Wiener, William Koltun, Patrick Griffin, Laura Barrow, Mary Beth Layton, Leslie Magnus
Publikováno v:
The American Journal of Gastroenterology
Objectives: This study assessed the efficacy and safety of plecanatide, a guanylate cyclase-C (GC-C) agonist and the first uroguanylin analog approved for the treatment of chronic idiopathic constipation (CIC). Methods: This phase III, multicenter, d
Autor:
Fernand, Labrie, Leonard, Derogatis, David F, Archer, William, Koltun, Andrée, Vachon, Douglas, Young, Louise, Frenette, David, Portman, Marlene, Montesino, Isabelle, Côté, Julie, Parent, Lyne, Lavoie, Adam, Beauregard, Céline, Martel, Mario, Vaillancourt, John, Balser, Érick, Moyneur
Publikováno v:
The Journal of Sexual Medicine. 12:2401-2412
Introduction Previous data have shown that intravaginal dehydroepiandrosterone (DHEA, prasterone) improved all the domains of sexual function, an effect most likely related to the local formation of androgens from DHEA. Aims To confirm in a placebo-c
Autor:
William Koltun, Peter A. Leone, Seth Hetherington, Anna Wald, Bin Zhang, Lori Panther, Gregg Lucksinger, Terri Warren, Richard H. Beigi, Sybil Tasker, David I. Bernstein, Nicholas Van Wagoner, Stephen K. Tyring, John D. Kriesel, Kenneth H. Fife, Richard M. Novak, Amy Morris, Lisa K. McNeil
Publikováno v:
J Infect Dis
Background GEN-003 is a candidate therapeutic vaccine for genital herpes simplex virus type 2 (HSV-2). We compared virologic and clinical impact of varying GEN-003 doses. Methods Adults with symptomatic HSV-2 received placebo or GEN-003 (30 or 60 µg
Autor:
Chalom Sayada, William Koltun, William M. Geisler, Raymond F. Schinazi, Judy S. Mathew, Selwyn J. Hurwitz, Franklin G. Morgan, Annette Mayes, Maria Luz G. Pascual, Byron E. Batteiger, Sijia Tao
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:4014-4019
A randomized, double-blind study comparing single-dose chlamydia therapies of oral rifalazil (25 mg) and azithromycin (1 g) was conducted in 82 women with uncomplicated genital Chlamydia trachomatis infection. The microbiologic cure rate of C. tracho
Autor:
William Koltun, Michael P. Diamond, Ping Jiang, Joshua Burke, W. Paul Dmowski, Bruce R. Carr, Roland Jimenez, Kristof Chwalisz, Christopher F. O'Brien, Elizabeth Garner
Publikováno v:
Reproductive Sciences. 21:363-371
This Phase 2 study evaluated the safety and efficacy of elagolix for treating endometriosis-associated pain. A total of 155 women with laparoscopically confirmed endometriosis were randomized to placebo, elagolix 150 mg, or elagolix 250 mg once daily
Autor:
Ruth A. Muenzen, Stephanie N. Taylor, Edward W. Hook, Byron E. Batteiger, William Koltun, William M. Geisler, Leandro Mena, John Caminis, Andrea R. Thurman, Toby A. Vaughn, Nader Abdelsayed, Miriam P. Annett, John Burigo
Publikováno v:
Clinical Infectious Diseases. 55:82-88
Background. Recent studies have raised concern about efficacy of azithromycin for Chlamydia trachomatis infection. Research investigating new antibiotic regimens for chlamydia has been sparse, especially regimens that may reduce adherence difficultie
Publikováno v:
Obstetrics & Gynecology. 111:1343-1351
To investigate the safety and efficacy of a transdermal estradiol (E2) spray in women with postmenopausal vasomotor symptoms.A randomized, double-blind, placebo-controlled, multicenter, parallel-group clinical trial was conducted. Postmenopausal wome
Autor:
David F, Archer, Fernand, Labrie, Céline, Bouchard, David J, Portman, William, Koltun, Leonello, Cusan, Claude, Labrie, Isabelle, Côté, Lyne, Lavoie, Céline, Martel, John, Balser, Douglas, Young
Publikováno v:
Menopause (New York, N.Y.). 22(9)
This study aims to confirm the local effects of intravaginal prasterone on moderate to severe dyspareunia, a symptom of vulvovaginal atrophy (VVA) associated with menopause.In a prospective, randomized, double-blind, placebo-controlled phase III clin
Autor:
Gregg Lucksinger, Seth Hetherington, Kenneth H. Fife, David I. Bernstein, Stephen K. Tyring, Richard M. Novak, Jason Chan, Peter A. Leone, Sybil A. Tasker, Nicholas Van Wagoner, John D. Kriesel, Jacob Lalezari, Lori Panther, Richard H. Beigi, William Koltun, Terri Warren, Anna Wald
Publikováno v:
Open Forum Infectious Diseases. 2
RESULTS: Patient Demographics 898 1The University of Alabama at Birmingham, Birmingham, AL, 2Medical Center for Clinical Research, San Diego, CA, 3Tekton Research, Austin, TX, 4Westover Heights Clinic, Portland, OR, 5Center for Clinical Studies, Hous