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pro vyhledávání: '"William Karshin"'
Autor:
Yu Min Kuo, Joel B. Kirkpatrick, Jun Li, Donald Tom, Alex E. Roher, Jiahan Yu, Lanny J. Haverkamp, William Karshin, Dana Giulian
Publikováno v:
Scopus-Elsevier
Alzheimer's disease (AD) is found to have striking brain inflammation characterized by clusters of reactive microglia that surround senile plaques. A recent study has shown that microglia placed in contact with isolated plaque fragments release neuro
Autor:
Joel B. Kirkpatrick, Lanny J. Haverkamp, Xia Li, Jun Li, Dana Giulian, Donald Tom, William Karshin, Jenny Yu
Publikováno v:
Neurochemistry international. 27(1)
Senile plaques found in the brains of patients with Alzheimer's disease (AD) are surrounded by clusters of reactive microglia. Isolated human microglia placed in contact with plaques in vitro are activated to release a factor which is toxic to neuron