Zobrazeno 1 - 6
of 6
pro vyhledávání: '"William K. Porteous"'
Autor:
J. David Curb, Murray R. Grigor, William K. Porteous, Steven C. Hunt, Caryn M. Thompson, Eugenie L. Harris, Eric Boerwinkle, Nadia E. Barreto, Marijo Bilusic, Carol Moreno, Michael Tschannen, Anne E. Kwitek, Howard J. Jacob, Alan B. Weder
Publikováno v:
Croatian Medical Journal. 49:586-599
To determine the independent and combined effects of three quantitative trait loci (QTL) for blood pressure in the Genetically Hypertensive (GH/Omr) rat by generating and characterizing single and combined congenic strains that have QTL on rat chromo
Autor:
William K. Porteous, Howard J. Jacob, Eugenie L. Harris, Mary A. Granados, Andre M. van Rij, Monika Stoll, Gregory T. Jones
Publikováno v:
Physiological Genomics. 6:183-189
A trait of vascular fragility, characterized by the formation of abrupt defects within the elastic laminae of the abdominal aorta, has been identified in Brown Norway (BN) rats. These lesions are greatly exacerbated in F1rats from a BN × New Zealand
Autor:
Carolyn M. Porteous, Michael P. Murphy, Carolyn V. Coulter, Robin A.J. Smith, William K. Porteous, Geoffrey F. Kelso, Gillian Hughes, Elizabeth C. Ledgerwood
Publikováno v:
Journal of Biological Chemistry. 276:4588-4596
With the recognition of the central role of mitochondria in apoptosis, there is a need to develop specific tools to manipulate mitochondrial function within cells. Here we report on the development of a novel antioxidant that selectively blocks mitoc
Autor:
Philip W. Sheard, Michael P. Murphy, Andrew M. James, Serena J. Hyslop, Michael A. Packer, Cheng-Yoong Pang, Julian V. Melton, Carolyn M. Porteous, Yau-Huei Wei, William K. Porteous
Publikováno v:
European Journal of Biochemistry. 257:192-201
Mutations and deletions in mitochondrial DNA (mtDNA) lead to a number of human diseases characterized by neuromuscular degeneration. Accumulation of truncated mtDNA molecules (delta-mtDNA) lacking a specific 4977-bp fragment, the common deletion, lea
Autor:
Marijo Bilušić, Carol Moreno, Nadia E. Barreto, Michael R. Tschannen, Eugenie L. Harris, William K. Porteous, Caryn M. Thompson, Murray R. Grigor, Alan Weder, Eric Boerwinkle, Steven C. Hunt, J. David Curb, Howard J. Jacob, Anne E. Kwitek
Publikováno v:
Croatian Medical Journal
Volume 49
Issue 5
Volume 49
Issue 5
Aim To determine the independent and combined effects of three quantitative trait loci (QTL) for blood pressure in the Genetically Hypertensive (GH/Omr) rat by generating and characterizing single and combined congenic strains that have QTL on rat ch
Autor:
William K. Porteous, Daniel Shannon, Michael P. Murphy, Ruth D. Appleby, Yau-Huei Wei, Andrew M. James, Gillian Hughes
Publikováno v:
European journal of biochemistry. 262(1)
Mammalian mitochondrial DNA (mtDNA) encodes 13 polypeptide components of oxidative phosphorylation complexes. Consequently, cells that lack mtDNA (termed rho degrees cells) cannot maintain a membrane potential by proton pumping. However, most mitocho