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RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice
Autor:
Kimberly J. Jurgensen, William K. J. Skinner, Bryan Oronsky, Nacer D. Abrouk, Andrew E. Graff, Reid D. Landes, William E. Culp, Thomas A. Summers, Lynnette H. Cary
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The present studies evaluate the in vivo prophylactic radioprotective effects of 1-bromoacetyl-3, 3-dinitroazetidine (RRx-001), a phase III anticancer agent that inhibits c-myc and downregulates CD-47, after total body irradiation (TBI), in lethally
Externí odkaz:
https://doaj.org/article/07bf6d1f47074698979c2b0221d0f085