Zobrazeno 1 - 10
of 160
pro vyhledávání: '"William K Kaufmann"'
Autor:
Natalie Saini, Steven A Roberts, Leszek J Klimczak, Kin Chan, Sara A Grimm, Shuangshuang Dai, David C Fargo, Jayne C Boyer, William K Kaufmann, Jack A Taylor, Eunjung Lee, Isidro Cortes-Ciriano, Peter J Park, Shepherd H Schurman, Ewa P Malc, Piotr A Mieczkowski, Dmitry A Gordenin
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006385 (2016)
Accumulation of somatic changes, due to environmental and endogenous lesions, in the human genome is associated with aging and cancer. Understanding the impacts of these processes on mutagenesis is fundamental to understanding the etiology, and impro
Externí odkaz:
https://doaj.org/article/148d642d05be4115befb367ef75ad6b5
Autor:
Jacquelyn J. Bower, Leah D. Vance, Matthew Psioda, Stephanie L. Smith-Roe, Dennis A. Simpson, Joseph G. Ibrahim, Katherine A. Hoadley, Charles M. Perou, William K. Kaufmann
Publikováno v:
npj Breast Cancer, Vol 3, Iss 1, Pp 1-12 (2017)
Cell cycle: Breast cancer subtypes exhibit distinct checkpoint dysfunctions Unique subtypes of breast cancer display distinctive patterns of genomic instability that affect cell division. Jacquelyn J. Bower and colleagues at the University of North C
Externí odkaz:
https://doaj.org/article/94f441a22a494a089060ea8ad3b50c9e
Autor:
William K. Kaufmann, Richard S. Paules, Pierre R. Bushel, Feng Cao, Dennis A. Simpson, Yingchun Zhou, Jeff Chou, Tong Zhou
Supplementary Table S1 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human Fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353f4819ae0809f91b0962b06ede00f0
https://doi.org/10.1158/1541-7786.22520628
https://doi.org/10.1158/1541-7786.22520628
Autor:
William K. Kaufmann, Richard S. Paules, Pierre R. Bushel, Feng Cao, Dennis A. Simpson, Yingchun Zhou, Jeff Chou, Tong Zhou
The relationships between profiles of global gene expression and DNA damage checkpoint functions were studied in cells from patients with ataxia telangiectasia (AT). Three telomerase-expressing AT fibroblast lines displayed the expected hypersensitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4133a81999fac3e35ea2411300c02e01
https://doi.org/10.1158/1541-7786.c.6542700.v1
https://doi.org/10.1158/1541-7786.c.6542700.v1
Autor:
Norman E. Sharpless, David L. Rimm, William K. Kaufmann, Channing J. Der, James E. Bear, Menashe Bar-Eli, Tong Zhou, Glynis Scott, Jack Arbiser, Shannon Penland, Honglin Hao, Chad Torrice, Michael Leslie, Aaron J. Berger, Melissa Cregger, Nancy E. Thomas, Janiel M. Shields
Supplementary Table 2 from Lack of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Signaling Shows a New Type of Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0277b3eba0052e97a19e0ba48d46f512
https://doi.org/10.1158/0008-5472.22365716.v1
https://doi.org/10.1158/0008-5472.22365716.v1
Autor:
Norman E. Sharpless, David L. Rimm, William K. Kaufmann, Channing J. Der, James E. Bear, Menashe Bar-Eli, Tong Zhou, Glynis Scott, Jack Arbiser, Shannon Penland, Honglin Hao, Chad Torrice, Michael Leslie, Aaron J. Berger, Melissa Cregger, Nancy E. Thomas, Janiel M. Shields
Supplementary Legends from Lack of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Signaling Shows a New Type of Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a3ef03ae4bfe9af8324dc38c85519
https://doi.org/10.1158/0008-5472.22365722
https://doi.org/10.1158/0008-5472.22365722
Autor:
Norman E. Sharpless, David L. Rimm, William K. Kaufmann, Channing J. Der, James E. Bear, Menashe Bar-Eli, Tong Zhou, Glynis Scott, Jack Arbiser, Shannon Penland, Honglin Hao, Chad Torrice, Michael Leslie, Aaron J. Berger, Melissa Cregger, Nancy E. Thomas, Janiel M. Shields
The majority of human melanomas harbor activating mutations of either N-RAS or its downstream effector B-RAF, which cause activation of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) kinase and the ERK MAPK cascad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e944e6c032748604acb5e2688eb188
https://doi.org/10.1158/0008-5472.c.6494831.v1
https://doi.org/10.1158/0008-5472.c.6494831.v1
Autor:
Aziz Sancar, William K. Kaufmann, Stephanie L. Smith-Roe, Janiel M. Shields, Joyce T. Reardon, Michael G. Kemp, Shobhan Gaddameedhi
Sunlight UV exposure produces DNA photoproducts in skin that are repaired solely by nucleotide excision repair in humans. A significant fraction of melanomas are thought to result from UV-induced DNA damage that escapes repair; however, little eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c59592343e2d40bdbf255bc675aa357
https://doi.org/10.1158/0008-5472.c.6500036.v1
https://doi.org/10.1158/0008-5472.c.6500036.v1
Autor:
Aziz Sancar, William K. Kaufmann, Stephanie L. Smith-Roe, Janiel M. Shields, Joyce T. Reardon, Michael G. Kemp, Shobhan Gaddameedhi
Supplementary Table 1 from Similar Nucleotide Excision Repair Capacity in Melanocytes and Melanoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb57ed0ebdc10363f63f8eacdc0be74
https://doi.org/10.1158/0008-5472.22381940
https://doi.org/10.1158/0008-5472.22381940
Autor:
Charles M. Perou, William K. Kaufmann, Jerry W. Shay, Per Eystein Lønning, Anne-Lise Børresen-Dale, Brittney-Shea Herbert, Therese Sørlie, Katherine A. Hoadley, Melissa A. Troester
Recent microarray studies have identified distinct subtypes of breast tumors that arise from different cell types and that show statistically significant differences in patient outcome. To gain insight into these differences, we identified in vitro a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dcbeacda29d593b9ce25d3e9188315
https://doi.org/10.1158/0008-5472.c.6493835
https://doi.org/10.1158/0008-5472.c.6493835