Zobrazeno 1 - 10
of 120
pro vyhledávání: '"William K, Kelly"'
Autor:
Nicole M. Naranjo, Anne Kennedy, Anna Testa, Cecilia E. Verrillo, Adrian D. Altieri, Rhonda Kean, D. Craig Hooper, Jindan Yu, Jonathan Zhao, Oliver Abinader, Maxwell W. Pickles, Adam Hawkins, William K. Kelly, Ramkrishna Mitra, Lucia R. Languino
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Prostate cancer has heterogeneous growth patterns, and its prognosis is the poorest when it progresses to a neuroendocrine phenotype. Using bioinformatic analysis, we evaluated RNA expression of neuroendocrine genes in a panel of five different cance
Externí odkaz:
https://doaj.org/article/cc3eebc16b874208b219a26ee873f2eb
Autor:
Cecilia E. Verrillo, Fabio Quaglia, Christopher D. Shields, Stephen Lin, Andrew V. Kossenkov, Hsin‐Yao Tang, David Speicher, Nicole M. Naranjo, Anna Testa, William K. Kelly, Qin Liu, Benjamin Leiby, Luca Musante, Khalid Sossey‐Alaoui, Navneet Dogra, Tzu‐Yi Chen, Dario C. Altieri, Lucia R. Languino
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract It is known that small extracellular vesicles (sEVs) are released from cancer cells and contribute to cancer progression via crosstalk with recipient cells. We have previously reported that sEVs expressing the αVβ3 integrin, a protein upre
Externí odkaz:
https://doaj.org/article/04359d9772ad413f94e97e0367c5aad3
Autor:
Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter McCue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, Lucia R. Languino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Androgen deprivation therapies aimed to target prostate cancer (PrCa) are only partially successful given the occurrence of neuroendocrine PrCa (NEPrCa), a highly aggressive and highly metastatic form of PrCa, for which there is no effective
Externí odkaz:
https://doaj.org/article/3eeb18d3b89f4f6090553922e8d4285e
Autor:
Zachary T. Elliott, Zachary Goldberg, Ramez Philips, Jennifer M. Johnson, Margaret T. Kasner, William K. Kelly, Sarah Osipowicz, Rachael Dampman, Joseph M. Curry
Publikováno v:
Clinics and Practice, Vol 12, Iss 5, Pp 692-700 (2022)
Progress in the management of rare diseases, including rare cancers, is dependent upon clinical trials; however, as many as 32% of rare-disease trials go uncompleted or unpublished due to insufficient accrual. Monitoring practices may differ between
Externí odkaz:
https://doaj.org/article/a054b194539e432596ee7306284b1d2e
Publikováno v:
European urology [Eur Urol] 2010 Feb; Vol. 57 (2), pp. e18-9; author reply e20. Date of Electronic Publication: 2009 Oct 20.
Autor:
Xiang‐Lin Tan, Jian‐Yu E, Yong Lin, Timothy R. Rebbeck, Shou‐En Lu, Mingyi Shang, William K. Kelly, Anthony D'Amico, Mark N. Stein, Lanjing Zhang, Thomas L. Jang, Isaac Yi Kim, Kitaw Demissie, Anna Ferrari, Grace Lu‐Yao
Publikováno v:
Cancer Medicine, Vol 9, Iss 7, Pp 2379-2389 (2020)
Abstract Background Pre‐clinical studies suggest that metformin and statins may delay prostate cancer (PCa) metastases; however, data in humans are limited. To the best of our knowledge, this is the first human study aimed to quantify the individua
Externí odkaz:
https://doaj.org/article/c2361380119f40b3a468055abbe17f57
Autor:
Piotr Chlosta, Tomasz Drewa
Publikováno v:
European Urology. 57:e18-e19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f6447eaa6e7530397b41e0f89e5652f
https://doi.org/10.1016/j.eururo.2009.10.021
https://doi.org/10.1016/j.eururo.2009.10.021
Autor:
Michael J. Morris, Howard I. Scher
Publikováno v:
European Urology. 57:e20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d204ff5fffd7e34f6ae5382b27b7326c
https://doi.org/10.1016/j.eururo.2009.10.022
https://doi.org/10.1016/j.eururo.2009.10.022
Autor:
Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W Goodrich, Peter McCue, Andrew V Kossenkov, Amy C Mandigo, Karen E Knudsen, Paul H Weinreb, Eva Corey, William K Kelly, Lucia R Languino
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244985 (2021)
Neuroendocrine prostate cancer (NEPrCa) arises de novo or after accumulation of genomic alterations in pre-existing adenocarcinoma tumors in response to androgen deprivation therapies. We have provided evidence that small extracellular vesicles relea
Externí odkaz:
https://doaj.org/article/976a661517ad44058853982bade5a864
Autor:
Fabio Quaglia, Shiv Ram Krishn, George G. Daaboul, Srawasti Sarker, Raffaella Pippa, Josep Domingo-Domenech, Gaurav Kumar, Paolo Fortina, Peter McCue, William K. Kelly, Himisha Beltran, Qin Liu, Lucia R. Languino
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
The ability of small extracellular vesicles (sEVs) to reprogram cancer cells is well established. However, the specific sEV components able to mediate aberrant effects in cancer cells have not been characterized. Integrins are major players in mediat
Externí odkaz:
https://doaj.org/article/a987d4b64c7241bcbd7735801cedadae