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pro vyhledávání: '"William Jonathan Lederer"'
Autor:
Aman Ullah, Minh Tuan Hoang-Trong, William Jonathan Lederer, Raimond L. Winslow, Mohsin Saleet Jafri
Publikováno v:
Cells, Vol 11, Iss 12, p 1878 (2022)
Cardiovascular disease is the leading cause of death worldwide due in a large part to arrhythmia. In order to understand how calcium dynamics play a role in arrhythmogenesis, normal and dysfunctional Ca2+ signaling in a subcellular, cellular, and tis
Externí odkaz:
https://doaj.org/article/cd09b38068bb406e83b57392a1db191f
Publikováno v:
Membranes, Vol 11, Iss 12, p 989 (2021)
Calcium (Ca2+) plays a central role in the excitation and contraction of cardiac myocytes. Experiments have indicated that calcium release is stochastic and regulated locally suggesting the possibility of spatially heterogeneous calcium levels in the
Externí odkaz:
https://doaj.org/article/ca14fad6d55943daa49ad0776cef524a
Publikováno v:
Membranes, Vol 11, Iss 10, p 794 (2021)
Cardiac alternans is characterized by alternating weak and strong beats of the heart. This signaling at the cellular level may appear as alternating long and short action potentials (APs) that occur in synchrony with alternating large and small calci
Externí odkaz:
https://doaj.org/article/8b7df227c20e4b5caeb07d717325add2