Zobrazeno 1 - 6
of 6
pro vyhledávání: '"William J. Wei"'
Autor:
Daniel B. Callaghan, William J. Wei, Sanja Rogic, Warren M. Meyers, Kurt Haas, Fabian Meili, Iulia Dascalu, Paul Pavlidis, Wun Chey Sin
Publikováno v:
Am J Hum Genet
Summary SYNGAP1 is a neuronal Ras and Rap GTPase-activating protein with important roles in regulating excitatory synaptic plasticity. While many SYNGAP1 missense and nonsense mutations have been associated with intellectual disability, epilepsy, sch
Autor:
Emmanuelle Gras, Trang T. T. Vu, Nhu T. Q. Nguyen, Vuvi G. Tran, Yanjie Mao, Nguyen D. Tran, Nam H. Mai, Oliver X. Dong, David H. Jung, Natalia L. P. P. Iorio, Helvecio C. C. Povoa, Marcos Gabriel Pinheiro, Fabio Aguiar-Alves, William J. Weiss, Bo Zheng, Lily I. Cheng, Charles K. Stover, Bret R. Sellman, Antonio DiGiandomenico, Laure Gibault, Florent Valour, Binh An Diep
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundNew drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumon
Externí odkaz:
https://doaj.org/article/711b678c4c3e47ab9251fd8fcab51201
Publikováno v:
Journal of Investigative Surgery, Vol 32, Iss 8, Pp 706-715 (2019)
Purpose/Aim: In prey species, such as sheep, clinical signs of postoperative pain can manifest in subtle ways or may be concealed entirely. Previous publications describing pain assessment in ruminants focus on lameness and flock behavior, often in a
Externí odkaz:
https://doaj.org/article/36e9c24f8ede4ef1b04bab6c76df3076
Autor:
Gregory P. Howard, Nicole G. Bender, Prachi Khare, Borja López-Gutiérrez, Vincent Nyasembe, William J. Weiss, Jerry W. Simecka, Timothy Hamerly, Hai-Quan Mao, Rhoel R. Dinglasan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A successful malaria transmission blocking vaccine (TBV) requires the induction of a high antibody titer that leads to abrogation of parasite traversal of the mosquito midgut following ingestion of an infectious bloodmeal, thereby blocking the cascad
Externí odkaz:
https://doaj.org/article/b57a063ffd7d4e87aa007842f02ce0da
Autor:
Johan A. Kers, Robert E. Sharp, Anthony W. Defusco, Jae H. Park, Jin Xu, Mark E. Pulse, William J. Weiss, Martin Handfield
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Lantibiotics offer an untapped pipeline for the development of novel antibiotics to treat serious Gram-positive (+) infections including Clostridium difficile. Mutacin 1140 (MU1140) is a lantibiotic produced by Streptococcus mutans and acts via a nov
Externí odkaz:
https://doaj.org/article/b817fd7f62a14cda95a6d257a5f10e9a
Autor:
Trudy H. Grossman, Corey Fyfe, William O’Brien, Meredith Hackel, Mary Beth Minyard, Ken B. Waites, Jacques Dubois, Timothy M. Murphy, Andrew M. Slee, William J. Weiss, Joyce A. Sutcliffe
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT TP-271 is a novel, fully synthetic fluorocycline antibiotic in clinical development for the treatment of respiratory infections caused by susceptible and multidrug-resistant pathogens. TP-271 was active in MIC assays against key community re
Externí odkaz:
https://doaj.org/article/fc839a5a5190439892aac4f57b1d746e