Zobrazeno 1 - 5
of 5
pro vyhledávání: '"William J. Van Etten"'
Publikováno v:
RNA. 18:508-518
The bacteriophage λ's cI mRNA was utilized to examine the importance of the 5′-terminal phosphate on expression of leadered and leaderless mRNA in Escherichia coli. A hammerhead ribozyme was used to produce leadered and leaderless mRNAs, in vivo a
Publikováno v:
Journal of Bacteriology. 192:6482-6485
An AUG start codon is an important determinant of ribosome binding and expression of leaderless mRNAs in Escherichia coli . Using reporter constructs encoding mRNAs where the AUG start codon is preceded by untranslated leaders of various length and s
Autor:
Eric S. Lander, William J. Van Etten, David Altshuler, Lauren Linton, Victor J. Pollara, Jennifer Baldwin, Chris R. Cowles
Publikováno v:
Nature. 407:513-516
Most genomic variation is attributable to single nucleotide polymorphisms (SNPs), which therefore offer the highest resolution for tracking disease genes and population history. It has been proposed that a dense map of 30,000-500,000 SNPs can be used
Autor:
Lucinda Fulton, LaDeana W. Hillier, Michael C. Zody, John M. Higgins, Beverley J. Mortimore, Brian Schultz, David Willey, Lisa Cook, Lincoln Stein, Lauren Linton, Pui-Yan Kwok, Ravi Sachidanandam, Nicole Stange-Thomann, Charlotte G. Cole, Jennifer Baldwin, James C. Mullikin, David R. Bentley, Penny Coggill, Brian Gilman, Ruth Davenport, John Douglas Mcpherson, Steven Schmidt, Michael Dante, Steve Sherry, David Altshuler, William J. Van Etten, Catherine M. Rice, Jerzy M. Kakol, Sarah E. Hunt, Stephen F. Schaffner, Robert H. Waterston, Elaine R. Mardis, Brendan Blumenstiel, Eric S. Lander, David Reich, Mark J. Daly, Zemin Ning, Jane Rogers, Gabor T. Marth, Raymond T. Yeh, David Weissman
Publikováno v:
Nature. 409(6822)
We describe a map of 1.42 million single nucleotide polymorphisms (SNPs) distributed throughout the human genome, providing an average density on available sequence of one SNP every 1.9 kilobases. These SNPs were primarily discovered by two projects:
Autor:
Howard J. Jacob, Jo Gullings-Handley, Jian Lu, Steven D. Colman, Donna K. Slonim, Robbin Crane, Simon N. Twigger, Christopher Glenn, Anne E. Kwitek-Black, Marc Peden, Abraham P. Provoost, Donna M. Brown, Mary A. Granados, O. Scott Atkinson, Peter J. Tonellato, Steve Rozen, Jonathan M. Rothberg, Peter M. Young, Tim Mull, Kerri Russo, Robert G. Steen, Margit Knoblauch, Stephen F. Kingsmore, Diane Appel, Tara C. Matise, Mushira Kissebah, Detlev Ganten, William J. Van Etten, Eric S. Lander, Melanie Muir, Michael Popp
Publikováno v:
Scopus-Elsevier
The laboratory rat (Rattus norvegicus) is a key animal model for biomedical research. However, the genetic infrastructure required for connecting phenotype and genotype in the rat is currently incomplete. Here, we report the construction and integrat
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