Zobrazeno 1 - 10
of 128
pro vyhledávání: '"William J. Rice"'
Autor:
Purushotham Selvakumar, Ana I. Fernández-Mariño, Nandish Khanra, Changhao He, Alice J. Paquette, Bing Wang, Ruiqi Huang, Vaughn V. Smider, William J. Rice, Kenton J. Swartz, Joel R. Meyerson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The Kv1.3 potassium channel is expressed abundantly on activated T cells and mediates the cellular immune responses. Here, the authors report structures of the Kv1.3 potassium channel with and without immunoglobulin modulators, shedding light on the
Externí odkaz:
https://doaj.org/article/d07ce3fe1deb42c097bcb4bfddf1e075
Autor:
Kasahun Neselu, Bing Wang, William J. Rice, Clinton S. Potter, Bridget Carragher, Eugene Y.D. Chua
Publikováno v:
Journal of Structural Biology: X, Vol 7, Iss , Pp 100085- (2023)
Ice thickness is a critical parameter in single particle cryo-EM – too thin ice can break during imaging or exclude the sample of interest, while ice that is too thick contributes to more inelastic scattering that precludes obtaining high resolutio
Externí odkaz:
https://doaj.org/article/216ec6425afd4e4499642356c3da4b60
Autor:
Laura Y. Kim, William J. Rice, Edward T. Eng, Mykhailo Kopylov, Anchi Cheng, Ashleigh M. Raczkowski, Kelsey D. Jordan, Daija Bobe, Clinton S. Potter, Bridget Carragher
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable method for benchmarking both the hardware and software components of their single particle analysis workflow. The
Externí odkaz:
https://doaj.org/article/6aa7a9a89779493995198451bdcb91a6
Autor:
Ana B. Asenjo, Chandrima Chatterjee, Dongyan Tan, Vania DePaoli, William J. Rice, Ruben Diaz-Avalos, Mariena Silvestry, Hernando Sosa
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 759-768 (2013)
To elucidate the structural basis of the mechanism of microtubule depolymerization by kinesin-13s, we analyzed complexes of tubulin and the Drosophila melanogaster kinesin-13 KLP10A by electron microscopy (EM) and fluorescence polarization microscopy
Externí odkaz:
https://doaj.org/article/78884e3438f24af0aa84e3afc79ea9bf
Autor:
Krystal L Ching, Maren de Vries, Juan Gago, Kristen Dancel-Manning, Joseph Sall, William J Rice, Clea Barnett, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Feng-Xia Liang, Lorna E Thorpe, Bo Shopsin, Leopoldo N Segal, Meike Dittmann, Victor J Torres, Ken Cadwell
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001754 (2022)
Extracellular vesicles of endosomal origin, exosomes, mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Their diagnostic and therapeutic potential has been recognized
Externí odkaz:
https://doaj.org/article/cdfa812871bd4a9099e6eaf53a65cffd
Autor:
Changhao He, Jorge Mansilla-Soto, Nandish Khanra, Mohamad Hamieh, Victor Bustos, Alice J. Paquette, Andreina Garcia Angus, Derek M. Shore, William J. Rice, George Khelashvili, Michel Sadelain, Joel R. Meyerson
Publikováno v:
Sci Immunol
Chimeric antigen receptor (CAR) T cell therapy relies on T cells that are guided by synthetic receptors to target and lyse cancer cells. CARs bind to cell surface antigens through an scFv (binder), the affinity of which is central to determining CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9aef7f4096276919b5ed5d64647e300
https://europepmc.org/articles/PMC10228544/
https://europepmc.org/articles/PMC10228544/
Autor:
Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Jeremy S Dittman, William J Rice, Robin B Chan, Gilbert Di Paolo, Christopher T Beh, Anant K Menon
Publikováno v:
PLoS Biology, Vol 16, Iss 5, p e2003864 (2018)
Tether proteins attach the endoplasmic reticulum (ER) to other cellular membranes, thereby creating contact sites that are proposed to form platforms for regulating lipid homeostasis and facilitating non-vesicular lipid exchange. Sterols are synthesi
Externí odkaz:
https://doaj.org/article/efa2ddef75a04ab9ab955fc705402e73
Autor:
Da-Neng Wang, William J. Rice, Jinmei Song, Bing Wang, David B. Sauer, Joseph C Sudar, Jennifer Marden
Publikováno v:
FEBS J
The divalent anion sodium symporter (DASS) family contains both sodium-driven anion co-transporters and anion/anion exchangers. The family belongs to a broader Ion Transporter Superfamily (ITS), which comprises 24 families of transporters, including
Autor:
Purushotham Selvakumar, Ana I. Fernández-Mariño, Bing Wang, William J. Rice, Joel R. Meyerson, Kenton J. Swartz
Publikováno v:
Biophysical Journal. 122:13a-14a
Autor:
Tristan Bepler, Andrew J. Borst, Jonathan Bouvette, Giuseppe Cannone, Songye Chen, Anchi Cheng, Ao Cheng, Quanfu Fan, Fanis Grollios, Harshit Gupta, Meghna Gupta, Theo Humphreys, Paul T. Kim, Huihui Kuang, Yilai Li, Alex J. Noble, Ali Punjani, William J. Rice, Carlos Oscar S. Sorzano, Scott M. Stagg, Joshua Strauss, Lingbo Yu, Bridget Carragher, Clinton S. Potter
Publikováno v:
Journal of structural biology. 214(4)
This report provides an overview of the discussions, presentations, and consensus thinking from the Workshop on Smart Data Collection for CryoEM held at the New York Structural Biology Center on April 6-7, 2022. The goal of the workshop was to addres