Zobrazeno 1 - 10
of 36
pro vyhledávání: '"William J. McGahren"'
Autor:
Marshall M. Siegel, May Dean-Ming Lee, George O. Morton, Conway C. Chang, Donald B. Borders, G. A. Ellestad, William J. McGahren, T. S. Dunne
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc69e17cfb5177fe3b69946ad4a60c2
https://doi.org/10.1002/chin.199224267
https://doi.org/10.1002/chin.199224267
Autor:
Conway C. Chang, William J. McGahren, George A. Ellestad, Donald B. Borders, May D. Lee, T. S. Dunne, Marshall M. Siegel, George O. Morton
Publikováno v:
Journal of the American Chemical Society. 114:985-997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fc25eddcff1276264028657e186a8f
https://doi.org/10.1021/ja00029a030
https://doi.org/10.1021/ja00029a030
Publikováno v:
The Journal of Antibiotics. 36:1683-1690
The epimerization of avoparcin entities is discussed in some detail. The absolute stereochemistry of avoparcin is now known since the N-methyl terminal amino acid of the aglycone has been isolated and shown to exhibit negative optical rotation and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75438df947524366da7912a45028c76
https://doi.org/10.7164/antibiotics.36.1683
https://doi.org/10.7164/antibiotics.36.1683
Autor:
Jesse L. Baker, George O. Morton, John Henry Edward James Martin, G. A. Ellestad, F. Maurice Lovell, Nancy A. Perkinson, Ronald T. Hargreaves, William J. McGahren, Jesse Gamble
Publikováno v:
Carbohydrate Research. 89:237-247
Three molecules of l -ristosamine (3-amino-2,3,6-trideoxy- l - ribo -hexopyranose) condense with one molecule of ammonia to give a stable compound [1.1′.1′′-(dodecahydro-1,4,7,9 b -tetrazaphenalene-2,5,8-trityl)tri-1,2-propanediol] reminiscent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5bd8d4c229b5d4f703a975f8cec70de
https://doi.org/10.1016/s0008-6215(00)85249-0
https://doi.org/10.1016/s0008-6215(00)85249-0
Publikováno v:
The Journal of Organic Chemistry. 42:1282-1286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784ecf885fe436da9ff0a2e0afd8afab
https://doi.org/10.1021/jo00428a003
https://doi.org/10.1021/jo00428a003
Autor:
G. A. Ellestad, Marshall M. Siegel, George O. Morton, William J. McGahren, John C. James, Donald B. Borders
Publikováno v:
The Journal of Antibiotics. 39:1541-1550
The behavior of the free acid and ammonium salt of maduramicin towards heat and alcohols is examined. In refluxing lower alcohols the free acid material is decarboxylated. In addition a bisketal decarboxylated compound as well as an A-ring monoketal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ab7e43c1b6e7e0f0b268c4b233058c
https://doi.org/10.7164/antibiotics.39.1541
https://doi.org/10.7164/antibiotics.39.1541
Autor:
William J. McGahren, N. Canfield, Marshall M. Siegel, John C. James, R. A. Leese, G. A. Ellestad, George O. Morton
Publikováno v:
The Journal of Antibiotics. 39:447-456
The formation of monovalent and divalent salt complexes of maduramicin is described and the 13C NMR chemical shift assignments of these materials are tabulated and discussed. In the spectrum of the thallium salt, 20 of the 47 signals are split due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8883862a52b48bca1309777f5e17a8c2
https://doi.org/10.7164/antibiotics.39.447
https://doi.org/10.7164/antibiotics.39.447
Publikováno v:
Science. 240:1198-1201
Calicheamicin gamma 1I is a recently discovered diyne-ene--containing antitumor antibiotic with considerable potency against murine tumors. In vitro, this drug interacts with double-helical DNA in the minor groove and causes site-specific double-stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4966616e438b8c19979ab321aa2931d9
https://doi.org/10.1126/science.3240341
https://doi.org/10.1126/science.3240341
Autor:
Marshall M. Siegel, Michael J Pastel, George O. Morton, G. A. Ellestad, Donald B. Borders, Philip R. Hamann, William J. McGahren, Nada Zein
Publikováno v:
Tetrahedron Letters. 30:3033-3036
Calicheamicin γ1I ( 1 ) reacts with Ph3P to form a dimeric trisulfide ( 3 ), MeSSMe, Ph3PS, and Ph3PO, as well as an aromatic degradation product ( 2 ). The oxygen of the Ph3PO is derived from O2. Calicheamicin also reacts with thiols to produce dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::640bcbf9c74f4e2b58c77c40b96c6f4e
https://doi.org/10.1016/s0040-4039(00)99395-x
https://doi.org/10.1016/s0040-4039(00)99395-x
Autor:
William J. McGahren, George O. Morton, N. A. Kuck, G. A. Ellestad, F. Barbatschi, R. A. Leese
Publikováno v:
The Journal of Antibiotics. 36:1671-1682
The isolation and characterization of many of the components of the avoparcin complex are described. A number of mild degradations products from this complex are similarly treated. Conditions for the analytical and preparative HPLC resolution of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68145d5379a0943774e32be152531d
https://doi.org/10.7164/antibiotics.36.1671
https://doi.org/10.7164/antibiotics.36.1671