Zobrazeno 1 - 10
of 22
pro vyhledávání: '"William J. Leahey"'
Autor:
Paul K. Hamilton, Kristopher S. Lyons, Gary E. McVeigh, Richard D. Plumb, Adrian Devine, Dennis Johnston, William J. Leahey, Sinead M. Hughes
Publikováno v:
Clinical Science. 118:359-366
In addition to lowering cholesterol, statins may alter endothelial release of the vasodilator NO and harmful superoxide free radicals. Statins also reduce cholesterol intermediates including isoprenoids. These are important for post-translational mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee2b87148e92d9ce9b0fc45db2a8af0
https://doi.org/10.1042/cs20090388
https://doi.org/10.1042/cs20090388
Autor:
A. L. Bell, Gary E. McVeigh, Andrew J. Gamble, Richard Plumb, Michael B. Finch, Fiona M. O’Prey, Adrian Devine, Dennis Johnston, William J. Leahey, Stephen A. Wright, Derrick J. Rea, R. Canice McGivern
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2281-2287
Objective— Impaired flow-mediated dilation (FMD) occurs in disease states associated with atherosclerosis, including SLE. The primary hemodynamic determinant of FMD is wall shear stress, which is critically dependent on the forearm microcirculation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a023ed0f9178893962c8f2c0f92b31b
https://doi.org/10.1161/01.atv.0000238351.82900.7f
https://doi.org/10.1161/01.atv.0000238351.82900.7f
Autor:
Lana J. Dixon, G. Dennis Johnston, Lawrence T. McGrath, Naglaa A. El-Sherbeeny, Paul Hamilton, William J. Leahey, C G Hanratty, David R. Morgan, Gary E. McVeigh
Publikováno v:
The American Journal of Cardiology. 97:547-551
We investigated the effects of omega-3 fatty acids administration on endothelium-dependent vasodilation in patients > or =65 years old who received treatment for chronic heart failure (CHF). Twenty patients (mean age 73 years; 15 men) with grade II a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bd646f83eb8180d5b803e0e7911816
https://doi.org/10.1016/j.amjcard.2005.08.075
https://doi.org/10.1016/j.amjcard.2005.08.075
Autor:
Gary E. McVeigh, Lana J. Dixon, Aine Madden, G. Dennis Johnston, Sinead M. Hughes, Welby Henry, William J. Leahey, Keith P. Rooney, Adrian Devine
Publikováno v:
American Journal of Hypertension. 18:839-843
Background Hypertension and diabetes are important independent risk factors for increased oxidative stress and increased cardiovascular risk. The combination of hypertension and diabetes results in a dramatic increase in cardiovascular risk. Enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83488e0971f57b47a96ed261036863c8
https://doi.org/10.1016/j.amjhyper.2005.01.004
https://doi.org/10.1016/j.amjhyper.2005.01.004
Autor:
Adrian Devine, David R. Morgan, William J. Leahey, Naglaa A. El-Sherbeeny, Sinead M. Hughes, G. Dennis Johnston, Gary E. McVeigh, Lana J. Dixon, Richard Plumb, Lawrence T. McGrath
Publikováno v:
Circulation. 107:1725-1728
Background— Impaired endothelium-mediated vasodilatation (EMVD) in congestive cardiac failure (CCF) has been linked to decreased nitric oxide (NO) bioavailability because of its interaction with vascular superoxide (O 2 ·− ), derived predominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d13cc49fc2a17a217b524978d9ea7f
https://doi.org/10.1161/01.cir.0000066283.13253.78
https://doi.org/10.1161/01.cir.0000066283.13253.78
Autor:
Adrian Devine, C G Hanratty, Lawrence T. McGrath, David G.A. Morgan, Lana J. Dixon, Martin Wilson, Gary E. McVeigh, Paul Hamilton, William J. Leahey
Publikováno v:
Circulation. 106:208-213
Background — The therapeutic benefits that accompany the continuous administration of organic nitrates are attenuated by the development of tolerance to the compounds. Altered superoxide production and NO bioavailability have been implicated in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1e9e64970e405195a4d9f5383227c3
https://doi.org/10.1161/01.cir.0000021600.84149.78
https://doi.org/10.1161/01.cir.0000021600.84149.78
Autor:
Fiona M. O’Prey, Dennis Johnston, Michelle T McHenry, William J. Leahey, Gary E. McVeigh, A. L. Bell, Adrian Devine, Stephen A. Wright, Michael B. Finch, Emeir M Duffy
Publikováno v:
Annals of the rheumatic diseases. 67(6)
To determine the clinical effect of dietary supplementation with low-dose omega-3-polyunsaturated fatty acids on disease activity and endothelial function in patients with systemic lupus erythematosus.A 24-week randomised double-blind placebo-control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180a9e381d2c3afc0aec7963b08dc4cc
https://pubmed.ncbi.nlm.nih.gov/17875549
https://pubmed.ncbi.nlm.nih.gov/17875549
Autor:
Sinead M. Hughes, Lana J. Dixon, G. Dennis Johnston, William J. Leahey, C G Hanratty, Keith P. Rooney, Gary E. McVeigh, David R. Morgan
Publikováno v:
European journal of heart failure. 6(7)
Background: Impaired endothelium-dependent and independent vasodilator responses in chronic heart failure (CHF) have been well described. Previous studies involved younger patients and omitted medications prior to study. Aims: We explored if new ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6372d2ed5b9ec7c92d96ab133b24aef
https://pubmed.ncbi.nlm.nih.gov/15556052
https://pubmed.ncbi.nlm.nih.gov/15556052
Autor:
David R. Morgan, Adrian Devine, Lana J. Dixon, Naglaa A. El-Sherbeeny, Gary E. McVeigh, William J. Leahey, G. Dennis Johnston, Sinead M. Hughes, Lawrence T. McGrath
Publikováno v:
Journal of the American College of Cardiology. 41(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214122a46a1b3c852ecef62cdea06744
Autor:
Adrian Devine, William J. Leahey, Gary E. McVeigh, Denise McDonald, Nuria Matesanz, Tom A. Gardiner, Grace Park, Hollie McAllister
Publikováno v:
Investigative Opthalmology & Visual Science. 51:6815
Retinal neovascularization (NV) is a serious complication of many ocular disease states, including diabetic retinopathy and retinopathy of prematurity (ROP). In these conditions, uncontrolled blood vessel growth results in severe vision loss; therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feec0150d0f70fe4747ba370df17ef25
https://doi.org/10.1167/iovs.10-5339
https://doi.org/10.1167/iovs.10-5339