Zobrazeno 1 - 10
of 120
pro vyhledávání: '"William J. Kupsky"'
Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma
Autor:
Anthony R. Guastella BS, Sharon K. Michelhaugh PhD, Neil V. Klinger MS, William J. Kupsky MD, Lisa A. Polin PhD, Otto Muzik PhD, Csaba Juhász MD, PhD, Sandeep Mittal MD, FRCSC, FACS
Publikováno v:
Molecular Imaging, Vol 15 (2016)
Increasing evidence demonstrates the immunosuppressive kynurenine pathway’s (KP) role in the pathophysiology of human gliomas. To study the KP in vivo, we used the noninvasive molecular imaging tracer α-[ 11 C]-methyl- l -tryptophan (AMT). The AMT
Externí odkaz:
https://doaj.org/article/bf123b80ad2a43db945e275c5eed7edf
Autor:
David O. Kamson, Sandeep Mittal, Amy Buth, Otto Muzik, William J. Kupsky, Natasha L. Robinette, Geoffrey R. Barger, Csaba Juhász
Publikováno v:
Molecular Imaging, Vol 12 (2013)
Differentiating high-grade gliomas from solitary brain metastases is often difficult by conventional magnetic resonance imaging (MRI); molecular imaging may facilitate such discrimination. We tested the accuracy of α[ 11 C]methyl-L-tryptophan (AMT)
Externí odkaz:
https://doaj.org/article/2868ab2e18d3485495b2472b7c268b2c
Autor:
Avanti, Gupte, Sandeep, Sood, William J, Kupsky, Deniz, Altinok, Steven, Miller, Sumita, Roy, Kanta, Bhambhani
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:e406-e409
DICER1 syndrome is a rare inherited tumor predisposition syndrome associated with an increased risk for several malignant and benign tumors. We present a patient with pineal parenchymal tumor of intermediate differentiation who was found to have a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0c39cb2b5b51b15f9ce1a7bae3a29b
https://doi.org/10.1097/mph.0000000000002518
https://doi.org/10.1097/mph.0000000000002518
Publikováno v:
Seizure. 93:95-101
Objective new-onset refractory status epilepticus (NORSE) is defined as de novo refractory seizures occurring in previously healthy adults, without a clear underlying etiology. Due to refractory seizures and insufficient understanding of pathophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed9571d2af1c2e728d0baa9bb6103e3
https://doi.org/10.1016/j.seizure.2021.09.018
https://doi.org/10.1016/j.seizure.2021.09.018
Publikováno v:
Pediatric Blood & Cancer. 68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::902700894001d3110b3b63e07933b70a
https://doi.org/10.1002/pbc.29029
https://doi.org/10.1002/pbc.29029
Autor:
Sam Kiousis, Hassan Fadel, Csaba Juhász, Neil V. Klinger, Sharon K. Michelhaugh, Rouba Ali-Fehmi, Sandeep Mittal, William J. Kupsky, Anthony R. Guastella
Publikováno v:
Journal of Neuro-Oncology. 139:239-249
INTRODUCTION: There is mounting evidence supporting the role of tryptophan metabolism via the kynurenine pathway (KP) in the pathogenesis of primary brain tumors. Under normal physiological conditions, the KP is the major catabolic pathway for the es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57075f562643f9b234bffbf785f2242c
https://doi.org/10.1007/s11060-018-2869-6
https://doi.org/10.1007/s11060-018-2869-6
Autor:
Richard Justin Garling, Rajkumar Agarwal, Catherine Peterson, Kallol Set, William J. Kupsky, Sandeep Sood, Eishi Asano
Publikováno v:
Pediatric Neurology. 92:73-75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b8b405822a0bbb00188332639073069
https://doi.org/10.1016/j.pediatrneurol.2018.11.011
https://doi.org/10.1016/j.pediatrneurol.2018.11.011
Autor:
Stephanie Toll, Avanti Gupte, Deniz Altinok, Sandeep Sood, Steven Miller, William J. Kupsky, Kanta Bhambhani
Publikováno v:
Neuro-Oncology
BACKGROUND DICER1 syndrome is a rare inherited tumor predisposition syndrome linked to an increased risk of several malignancies. Affected individuals most commonly develop pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors. Brain tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efdaab204f2e11f5746c21e9601af91
http://europepmc.org/articles/PMC7715204
http://europepmc.org/articles/PMC7715204
Autor:
Sharon K. Michelhaugh, Senthil K. Sundaram, Sandeep Sood, Csaba Juhász, Sandeep Mittal, Harry T. Chugani, Neil V. Klinger, William J. Kupsky
Publikováno v:
Neuropediatrics. 48:385-389
The recent identification of the somatic GNAQ mutation (c.548G > A) provides insight into the pathogenesis of Sturge–Weber syndrome (SWS). Although the primary SWS brain pathology is the leptomeningeal angiomatosis (LMA), cerebral cortical and whit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9accefac0eb4f715b71d0e3f5c4e4f6a
https://doi.org/10.1055/s-0037-1603515
https://doi.org/10.1055/s-0037-1603515
Autor:
Maysaa Basha, Sandeep Mittal, William J. Kupsky, Aashit Shah, Monica B. Dhakar, Kushak Suchdev
Publikováno v:
Neurocritical Care. 27:370-380
To identify the role of acute surgical intervention in the treatment of refractory status epilepticus (RSE). Retrospective review of consecutive patients who underwent epilepsy surgery from 2006 to 2015 was done to identify cases where acute surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fd1b8f948cccd931c8908572076d3c
https://doi.org/10.1007/s12028-017-0381-z
https://doi.org/10.1007/s12028-017-0381-z