Zobrazeno 1 - 10
of 297
pro vyhledávání: '"William J. Kaiser"'
Publikováno v:
Remote Sensing, Vol 13, Iss 9, p 1646 (2021)
As landscapes become increasingly fragmented, research into impacts from disturbance and how edges affect vegetation and community structure has become more important. Descriptive studies on how microclimate changes across sharp transition zones have
Externí odkaz:
https://doaj.org/article/16b8a6674811459583e7060e3fe7c8bc
Autor:
Robin Schwarzer, Amanda Fisher, Snehlata Kumari, George Kassiotis, Rebecca Lane, Remzi Onur Eren, Huipeng Jiao, Manolis Pasparakis, William J. Kaiser, George R. Young, Juan Lin, Laurens Wachsmuth
Publikováno v:
Nature
The biological function of Z-DNA and Z-RNA, nucleic acid structures with a left-handed double helix, is poorly understood1–3. Z-DNA-binding protein 1 (ZBP1; also known as DAI or DLM-1) is a nucleic acid sensor that contains two Zα domains that bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4961332333b469d5a77cdabcfad367db
https://doi.org/10.1038/s41586-020-2129-8
https://doi.org/10.1038/s41586-020-2129-8
Publikováno v:
ACM Transactions on Computing for Healthcare. 1:1-12
Wearable devices offer a promise of immense impact on worldwide global health by offering the potential for non-invasive, constantly vigilant, and low-cost monitoring of individual condition and fundamental advances in guiding healthcare. The urgency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c1b43f337a1534116209a6806fa728
https://doi.org/10.1145/3361561
https://doi.org/10.1145/3361561
Autor:
James A Rickard, Holly Anderton, Nima Etemadi, Ueli Nachbur, Maurice Darding, Nieves Peltzer, Najoua Lalaoui, Kate E Lawlor, Hannah Vanyai, Cathrine Hall, Aleks Bankovacki, Lahiru Gangoda, Wendy Wei-Lynn Wong, Jason Corbin, Chunzi Huang, Edward S Mocarski, James M Murphy, Warren S Alexander, Anne K Voss, David L Vaux, William J Kaiser, Henning Walczak, John Silke
Publikováno v:
eLife, Vol 3 (2014)
SHARPIN regulates immune signaling and contributes to full transcriptional activity and prevention of cell death in response to TNF in vitro. The inactivating mouse Sharpin cpdm mutation causes TNF-dependent multi-organ inflammation, characterized by
Externí odkaz:
https://doaj.org/article/dc7dcb5894674dcf8834bbc332067b93
Autor:
Xi-zhi J. Guo, Douglas R. Green, Maria Shubina, Avishekh Gautam, Ting Zhang, David F. Boyd, Diego A. Rodriguez, Siddharth Balachandran, Paul G. Thomas, Peter Vogel, Chaoran Yin, William J. Kaiser, Bart Tummers
Publikováno v:
The Journal of Experimental Medicine
Necroptosis is considered a fail-safe death modality deployed when apoptosis pathways are compromised, but whether necroptosis can limit a virus in the absence of apoptosis is unknown. This study demonstrates that necroptosis drives highly effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa31ebd9b25cfc5ae40992cf418483e
https://doi.org/10.1084/jem.20191259
https://doi.org/10.1084/jem.20191259
Autor:
William J. Kaiser, Jason W. Upton
Publikováno v:
Cell Host & Microbe. 21:290-293
Interrogation of murine cytomegalovirus (MCMV)-encoded cell-death suppressors revealed that necroptosis functions as a trap door to eliminate virally infected cells. This crucial host defense pathway is orchestrated by the sensing of infection by DAI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66cf6cb4ee743a62892e1c26db6c339
https://doi.org/10.1016/j.chom.2017.01.016
https://doi.org/10.1016/j.chom.2017.01.016
Autor:
Michael H. Wasko, William J. Kaiser, Per Borgstrom, Aman Mahajan, Xu Zhang, Yi Zheng, Kanav Saraf, Christopher I. Baek
Publikováno v:
CHASE
This paper presents a novel method for automatically detecting the onset of ventricular depolarization in electrocardiogram (ECG). In order to accommodate highly variable ECG morphologies in potentially noisy ECG signals, a weighted combination of fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe27572946101648f19f3e1ae42b3c3d
https://doi.org/10.1109/chase48038.2019.00010
https://doi.org/10.1109/chase48038.2019.00010
Autor:
Aman Mahajan, Kanav Saraf, William J. Kaiser, Christopher I. Baek, Xu Zhang, Michael H. Wasko, Per Borgstrom, Yi Zheng
Publikováno v:
EMBC
The irreversible damage and eventual heart failure caused by untreated aortic stenosis (AS) can be prevented by early detection and timely intervention. Prior work in the field of phonocardiogram (PCG) signal analysis has provided proof of concept fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57327b3a79888f4938c051d37fb8bc45
https://doi.org/10.1109/embc.2019.8857506
https://doi.org/10.1109/embc.2019.8857506
Autor:
Carolina B. López, Douglas R. Green, Jason W. Upton, Justin P. Ingram, Bart Tummers, Suraj Peri, Diego A. Rodriguez, Katherine B Ragan, Takumi Ishizuka, Jeremy Chase Crawford, Maria Shubina, Siddharth Balachandran, Chaoran Yin, Giovanni Quarato, Paul G. Thomas, David F. Boyd, William J. Kaiser, Ting Zhang, Jia Xue, Yan Xu
Publikováno v:
Cell
Influenza A virus (IAV) is a lytic RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain-like pseudokinase (MLKL)-dependent necroptosis in infected cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d536d0c4b36f868bab6d7bd6ff3c45
https://pubmed.ncbi.nlm.nih.gov/32200799
https://pubmed.ncbi.nlm.nih.gov/32200799
Autor:
Rebecca Lane, Hongyan Guo, Glenn F. Rall, Diego A. Rodriguez, Suresh H. Basagoudanavar, Roshan J. Thapa, Riley Williams, Michael Slifker, Christopher P. Dillon, Ting Zhang, Douglas R. Green, William J. Kaiser, Justin P. Ingram, Siddharth Balachandran, Amanda Fisher, Bart Tummers, Chaoran Yin
Publikováno v:
J Immunol
Receptor-interacting protein kinase 1 (RIPK1) regulates cell fate and proinflammatory signaling downstream of multiple innate immune pathways, including those initiated by TNF-α, TLR ligands, and IFNs. Genetic ablation of Ripk1 results in perinatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf69a36d6cf1df4dd869ea5e8957375f
https://pubmed.ncbi.nlm.nih.gov/31358656
https://pubmed.ncbi.nlm.nih.gov/31358656