Zobrazeno 1 - 5
of 5
pro vyhledávání: '"William J. Herring"'
Autor:
Akira Sawa, Lisa M. Ellerby, Christopher A. Ross, Michael R. Hayden, William J. Herring, Cheryl L. Wellington, Ted M. Dawson, Jon D. Wood, Valina L. Dawson, Frederick C. Nucifora
Publikováno v:
Journal of Biological Chemistry. 278:13047-13055
Dentatorubral and pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disorder similar to Huntington's disease, with clinical manifestations including chorea, incoordination, ataxia, and dementia. It is caused by an expansion of
Autor:
Valina L. Dawson, Jonathan Kushi, Jillian K. Cooper, Holly C. Seaman, William J. Herring, Matthew F. Peters, Ted M. Dawson, Frederick C. Nucifora, Christopher A. Ross
Publikováno v:
Molecular and Cellular Neuroscience. 14:121-128
Huntington's disease is a neurodegenerative disorder resulting from expansion of the polyglutamine region in huntingtin. Although huntingtin is normally cytoplasmic, in affected brain regions proteolytic fragments of mutant huntingtin containing the
Autor:
Marc F. Poitras, William J. Herring, Zhao-Qi Wang, Adam R. Berliner, Ted M. Dawson, Valina L. Dawson, Alicia Feldman, Allen S. Mandir, Daniel Guastella, Guy G. Poirier
Poly(ADP-ribose) polymerase (PARP-1), a nuclear enzyme that facilitates DNA repair, may be instrumental in acute neuronal cell death in a variety of insults including, cerebral ischemia,1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59529d7b5bf0b9f6bafba19ca12fcb04
https://europepmc.org/articles/PMC6772735/
https://europepmc.org/articles/PMC6772735/
Autor:
Masayuki Sasaki, Hui Huang, Sohyun Ahn, William J. Herring, Mirella Gonzalez-Zulueta, Ted M. Dawson, Valina L. Dawson, David D. Ginty
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(15)
Neuronal nitric oxide (NO) synthase (nNOS) is dynamically regulated in response to a variety of physiologic and pathologic stimuli. Although the dynamic regulation of nNOS is well established, the molecular mechanisms by which such diverse stimuli re
Autor:
Christopher A. Ross, Gabriele Schilling, Zachary Kaminsky, Valina L. Dawson, Ted M. Dawson, Jillian K. Cooper, David R. Borchelt, Michael Delanoy, Jamie Masone, Alan H. Sharp, Matthew F. Peters, Farhat A. Khan, William J. Herring
Publikováno v:
Human molecular genetics. 7(5)
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an expanding CAG repeat coding for polyglutamine in the huntingtin protein. Recent data have suggested the possibility that an N-terminal fragment of huntingtin may aggre