Zobrazeno 1 - 10
of 41
pro vyhledávání: '"William J. Hatton"'
Autor:
Chanjae Park, Wei Yan, Sean M Ward, Sung Jin Hwang, Qiuxia Wu, William J Hatton, Jong Kun Park, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18628 (2011)
Smooth muscle cells (SMCs) express a unique set of microRNAs (miRNAs) which regulate and maintain the differentiation state of SMCs. The goal of this study was to investigate the role of miRNAs during the development of gastrointestinal (GI) SMCs in
Externí odkaz:
https://doaj.org/article/0edfdd3b553544cca185fd0d78dfb690
Autor:
Sean M. Ward, Kenton M. Sanders, Noel G. McHale, William J. Hatton, Byoung H. Koh, Sang Don Koh, Gerard P. Sergeant, Keith D. Thornbury, Mark A. Hollywood, Rishiparna Roy
Publikováno v:
Journal of Cellular and Molecular Medicine
Specific classes of interstitial cells exist in visceral organs and have been implicated in several physiological functions including pacemaking and mediators in neurotransmission. In the bladder, Kit(+) interstitial cells have been reported to exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e728c3f6e847f77ef1117b53521bd9ee
https://doi.org/10.1111/j.1582-4934.2011.01506.x
https://doi.org/10.1111/j.1582-4934.2011.01506.x
Autor:
Caroline A. Cobine, Sean M. Ward, William J. Hatton, Kathleen D. Keef, Grant W. Hennig, Yulia Bayguinov
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G643-G656
The morphology of interstitial cells of Cajal (ICC) in the circular muscle layer of the cynomolgus monkey internal anal sphincter (IAS) and rectum and their relationship to sympathetic and nitrergic nerves were compared by dual-labeling immunohistoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7824fa2b921878598922b29e146847d9
https://doi.org/10.1152/ajpgi.00260.2009
https://doi.org/10.1152/ajpgi.00260.2009
Autor:
Junguk Han, William J. Hatton, Salah A. Baker, Sang Don Koh, Grant W. Hennig, Fiona C. Britton
Publikováno v:
Journal of Urology. 183:793-800
Mouse models of partial bladder outlet obstruction cause bladder hypertrophy. Expression of a number of ion channels is altered in hypertrophic detrusor muscle, resulting in bladder dysfunction. We determined whether mechanosensitive TREK-1 channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5c7af55b2bf7696b9ae93d75133bfd
https://doi.org/10.1016/j.juro.2009.09.079
https://doi.org/10.1016/j.juro.2009.09.079
Autor:
Linda L. Ye, Dayue Duan, Z. Maggie Huang, William J. Hatton, Fiona C. Britton, Chaithra Prasad
Publikováno v:
Journal of Molecular and Cellular Cardiology. 47:121-132
A novel Cl(-) inward rectifier channel (Cl,ir) encoded by ClC-2, a member of the ClC voltage-gated Cl(-) channel gene superfamily, has been recently discovered in cardiac myocytes of several species. However, the physiological role of Cl,ir channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2b3ca060ef55f04f6c4cc4a8e6baa8
https://doi.org/10.1016/j.yjmcc.2009.04.008
https://doi.org/10.1016/j.yjmcc.2009.04.008
Publikováno v:
Biochemical and Biophysical Research Communications. 384:476-481
Bestrophins form Ca 2+ -activated Cl − channels when they are expressed heterologously. Here we report the functional characterization of murine bestrophin 1 (mBest1). We isolated mBest1 transcript from mouse heart and analyzed the biophysical prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8ac5239b9740536dd46c0fd9b00605
https://doi.org/10.1016/j.bbrc.2009.05.008
https://doi.org/10.1016/j.bbrc.2009.05.008
Autor:
Phillip S. Keller, Paul Scowen, Dayue Duan, Ge-Xin Wang, Joseph R. Hume, Rebecca Evans, Cherie A. Singer, Linda Ye, Dazhi Xiong, Ilia A. Yamboliev, William J. Hatton, Honglin Tian, Shanti Rawat, Dean J. Burkin, Diana T. McCloskey
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 36:386-393
SUMMARY 1 ClC-3 has been proposed as a molecular candidate responsible for volume-sensitive outwardly rectifying anion channels (VSOAC) in cardiac and smooth muscle cells. To further test this hypothesis, we produced a novel line of transgenic mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9dd41789914616b4544f421d6ebe0b
https://doi.org/10.1111/j.1440-1681.2008.05069.x
https://doi.org/10.1111/j.1440-1681.2008.05069.x
Publikováno v:
Heart Rhythm. 3:1210-1220
Background An osmotic challenge activates volume-regulated chloride currents (I Cl,vol ), resulting in depolarization of the resting membrane potential and shortening of action potential duration (APD). I Cl,vol is activated in ischemia/reperfusion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f6037e6052007c6845a0bf37623215
https://doi.org/10.1016/j.hrthm.2006.06.026
https://doi.org/10.1016/j.hrthm.2006.06.026
Autor:
Burton Horowitz, William J. Hatton, Dayue Duan, Fiona C. Britton, Joseph R. Hume, Charles F. Rossow
Publikováno v:
Acta Physiologica. 187:5-19
Aim: This study investigated the functional role of the CIC-3 amino-terminus in channel regulation in response to changes in cell volume. Methods: Wild-type sClC-3 tagged with a green fluorescence protein (GFP) at the C-terminus was used as a templat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51022a3f1435e868318fcb2c07d6299
https://doi.org/10.1111/j.1748-1716.2006.01550.x
https://doi.org/10.1111/j.1748-1716.2006.01550.x
Autor:
Sean M. Wilson, Olga Ostrovskaya, Keith J. Murray, Cristiane del Corsso, William J. Hatton, Alison M. Gurney, Claire E. McAllister, Nick J. Spencer
Publikováno v:
Mechanisms of Ageing and Development. 127:315-323
Pathophysiological changes in arterial smooth muscle structure and function occur with aging and there are a number of reports illustrating reductions in vascular responsiveness with aging. While much is known about arterial remodeling and functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70558ebf5b8a542d6ba0c7f732dda78e
https://doi.org/10.1016/j.mad.2005.12.001
https://doi.org/10.1016/j.mad.2005.12.001