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pro vyhledávání: '"William J. Degnen"'
Autor:
Concordia C. L. Lo, Daniel Joaquin, Diego A. Moyá, Alexander Ramos, David W. Kastner, Stephen M. White, Blake L. Christensen, Joseph G. Naglich, William J. Degnen, Steven L. Castle
Publikováno v:
Chemical science. 13(7)
Simplified full-length analogs of yaku'amide A were designed with the aid of computations and then synthesized. The analog that was predicted to most closely resemble the structure of the natural product mimicked its anticancer activity.