Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William J. Cottrell"'
Publikováno v:
Lasers in Surgery and Medicine. 41:686-696
Background and Objective In a recently completed pilot clinical study at Roswell Park Cancer Institute, patients with superficial basal cell carcinoma (sBCC) received topical application of 20% 5-aminolevulinic acid (ALA) and were irradiated with 633
Publikováno v:
Clinical Cancer Research. 14:4475-4483
Purpose: In superficial basal cell carcinomas treated with photodynamic therapy with topical δ-aminolevulinic acid, we examined effects of light irradiance on photodynamic efficiency and pain. The rate of singlet-oxygen production depends on the pro
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G1166-G1177
Intracellular calcium concentration ([Ca2+]i) signals are central to the mechanisms underlying fluid and protein secretion in pancreatic and parotid acinar cells. Calcium release was studied in natively buffered cells following focal laser photolysis
Publikováno v:
Solid State Communications. 120:479-482
The far-infrared optical response of a light-modulating device fabricated from a thin YBa2Cu3O7 (YBCO) film is presented. A critical amount of current was used to switch the YBCO film between a substantially non-transparent superconducting state and
Publikováno v:
IEEE Photonics Technology Letters. 14:624-626
A technique is proposed to improve the optical response of a magnetooptic (MO) modulator. The rate at which a MO modulator can operate is limited by the relatively slow relaxation of electron spin carrier populations within the MO material. This rela
Publikováno v:
Lasers in surgery and medicine. 41(9)
In a recently completed pilot clinical study at Roswell Park Cancer Institute, patients with superficial basal cell carcinoma (sBCC) received topical application of 20% 5-aminolevulinic acid (ALA) and were irradiated with 633 nm light at 10-150 mW cm
Publikováno v:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XV.
Photodynamic therapy using 5-aminolevulinic acid is an effective therapy for treating basal cell carcinoma, characterized by high lesion clearance and excellent cosmetic outcomes. Treatment optimization and lesion-tailored treatments making use of re
Publikováno v:
Frontiers in Optics.
A retrofitted scattering spectroscopy system expands capabilities of a commercial inverted darkfield microscope. It measures wavelength- and angularly-resolved scattering using a spectrometer and the Fourier plane, respectively, and allows direct ima
Publikováno v:
Frontiers in Optics 2004/Laser Science XXII/Diffractive Optics and Micro-Optics/Optical Fabrication and Testing.
Instrumentation is developed for real-time determination of photodynamic therapy dosimetry in vivo, employing measurements of fluorescence emission spectra corrected for effects of dynamic tissue optical properties using white light diffuse reflectan
Publikováno v:
Optics Letters. 32:2348
We present the design, construction, and initial characterization of a multifunctional imaging/scattering spectroscopy system built around a commercial inverted microscope platform. The system enables co-registered brightfield, Fourier-filtered darkf