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of 11
pro vyhledávání: '"William J. Cady"'
Publikováno v:
JAMA: The Journal of the American Medical Association. 264:972
In Reply.— We appreciate the opportunity to respond to the comments of Cappuccio et al. The measurement of blood pressure at 12 ± 2 hours after receiving a dose was not an SD but a commonly used protocol requirement that all blood pressure measure
Autor:
Suzanne Oparil, William J. Cady, Michael A. Weber, William H. Stewart, Matthew R. Weir, James F. Burris
Publikováno v:
JAMA. 263:1507
This multicenter, factorial-design trial assessed the safety and additive antihypertensive efficacy of a slow-release (SR) formulation of diltiazem hydrochloride given alone or in combination with hydrochlorothiazide for treatment of mild to moderate
Autor:
William J. Cady
Publikováno v:
Clinical Research Practices and Drug Regulatory Affairs. 3:295-306
Federal regulations govern all areas of both preclinical and clinical research. These rules, proposed and currently enacted, serve to provide guidelines to the investigator for the proper conduct and ultimate acceptance by the federal agencies. It is
Autor:
R Michael Rubison, Richard L. Byyny, William J Cady, Alan S Nies, Patrick J Bryant, Robert W Piepho, Vaughn L Culbertson
Publikováno v:
Clinical Pharmacology and Therapeutics. 39:690-696
In a randomized, double-blind, dose-ranging trial, the acute antihypertensive effects of 7.5, 15, 30, 45, 60, 90, and 120 mg single daily doses of urapidil were compared with those of placebo in 10 patients with essential hypertension. Patients were
Publikováno v:
American Journal of Health-System Pharmacy. 36:92-95
Two case reports describing the treatment of digitoxin toxicity with cholestyramine resin are presented. Both female patients were receiving 100 microgram/day of digitoxin when toxicity occurred. In both patients, digitoxin was discontinued and hypok
Autor:
Ward A. Chambers, Charles S. Wilson, Terry L. Holcslaw, Alan D. Forker, Richard R. Miles, William J. Cady
Publikováno v:
American Heart Journal. 99:181-184
Publikováno v:
Drug Intelligence & Clinical Pharmacy. 17:645-648
Total joint arthroplasty is a common orthopedic procedure and requires prophylactic antibiotic coverage to prevent infections in the operated joint. The antibiotics routinely used for prophylaxis are the cephalosporins. This study compared bone, syno
Publikováno v:
Drug Intelligence & Clinical Pharmacy. 11:462-464
Three case reports indicate that infants below 10 kg in weight require greater mg/kg doses of phenytoin than larger infants or adults in order to achieve therapeutic plasma levels between 10–20 mcg/ml. In the absence of access to plasma phenytoin a
Publikováno v:
Toxicology letters. 7(4-5)
Male rats were treated with either adriamycin (2 mg/kg, i.v. weekly) or adriamycin and tetracycline (10 mg/kg, i.p., daily) for 8 weeks. Serum creatine phosphokinase (CPK) activity was measured after 8 weeks as an index of cardiotoxicity. Serum CPK w
Autor:
William J. Cady, H.B. Kostenbauder, John Hackman, Byron Young, Robert P. Rapp, Donald G. Perrier, Salvador Pancorbo
Publikováno v:
Annals of internal medicine. 85(3)
A parenteral dosing regimen was designed for the immediate attainment and maintenance of therapeutic plasma levels of phenytoin in patients requiring anticonvulsant therapy, but not able to tolerate oral medication. An intravenous dose of 10.7 mg/kg