Zobrazeno 1 - 10 of 42 pro vyhledávání: '"William J. Burtis"'
1
Immunoaffinity purification of parathyroid hormone-related protein from bovine milk and human keratinocyte-conditioned medium
Autor: Karl L. Insogna, Leonard M. Milstone, William J. Burtis, Andrew F. Stewart, Terrence L. Wu
Publikováno v: Journal of Bone and Mineral Research. 6:305-311
Parathyroid hormone-related proteins (PRHrP) are a novel family of proteins that appear to be responsible for humoral hypercalcemia of malignancy. Although PTHrP derived from human tumors have been purified and their N-terminal amino acid sequence de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08447d29b723f401c3409696055d24a
https://doi.org/10.1002/jbmr.5650060313
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2
The relative potency of a human tumor-derived PTH-like adenylate cyclase-stimulating preparation in three bioassays
Autor: Andrew F. Stewart, Arthur E. Broadus, Karl L. Insogna, Eleanor C. Weir, Terence Wu, William J. Burtis
Publikováno v: Journal of Bone and Mineral Research. 2:37-43
Three bioassays are widely employed for the measurement of PTH-like adenylate cyclase-stimulating factors (ACSFs) drived from tumors associated with humoral hypercalcemia of malignancy. These include renal cortical adenylate cyclase (RAC) assays, rat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaade1f14184a221b693bd052b2d329
https://doi.org/10.1002/jbmr.5650020107
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4
Parathyroid hormone-related peptide and 8701-BC breast cancer cell growth and invasion in vitro: evidence for growth-inhibiting and invasion-promoting effects
Autor: William J. Burtis, Claudio Luparello, Friedhelm Raue, M.A. Birch, James A. Gallagher
Publikováno v: Molecular and Cellular Endocrinology. 111:225-232
It has been previously reported that 8701-BC cells, derived from a primary carcinoma of the breast, constitutively express parathyroid hormone-related peptide (PTHrP) gene and that N-terminal PTHrP immunoreactivity can be found in cell medium. Here w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123e5f517067e764b7d6d12b63160ccc
https://doi.org/10.1016/0303-7207(95)03577-t
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5
Relative overexpression of the parathyroid hormone-related protein gene in human leiomyomas
Autor: Romana Angelika Nowak, Eleanor C. Weir, Dale L. Goad, William J. Burtis, Barbara E. Dreyer, Anastasia G. Daifotis
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 78:784-789
Uterine leiomyomas or fibroids are common among women of reproductive age, but their biology is poorly understood. The PTH-related protein (PTHrP) has been identified in a number of sites throughout the reproductive tract. We, therefore, examined whe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0057db7f29c1cb6b85dd951b1f4d8a90
https://doi.org/10.1210/jcem.78.3.8126157
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6
Accumulation of carboxy-terminal fragments of parathyroid hormone-related protein in renal failure
Autor: Pamela Dann, William J. Burtis, N E Soifer, John J. Orloff, Joseph P. Fodero
Publikováno v: Kidney International. 43(6):1371-1376
Accumulation of carboxy-terminal fragments of parathyroid hormone-related protein in renal failure. We have recently demonstrated elevations of separate amino- and carboxy-terminal parathyroid hormone-related protein (PTHrP) fragments in patients wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49b50e50a5281d6df00db1921bce9bb
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7
Preliminary characterization of circulating amino- and carboxy-terminal fragments of parathyroid hormone-related peptide in humoral hypercalcemia of malignancy
Autor: J P Fodero, William J. Burtis, A F Stewart, G Gaich, M Debeyssey
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 75:1110-1114
PTH-related peptide (PTHrP) immunoreactivity in plasma from six well characterized patients with humoral hypercalcemia of malignancy was characterized by gel filtration chromatography. An immunoradiometric assay directed against the N-terminal 74 ami
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eac9b0c8e80513e3613b26b9281e882
https://doi.org/10.1210/jcem.75.4.1400879
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8
Parathyroid hormone-related protein. Evidence for secretion of a novel mid-region fragment by three different cell types
Autor: N E Soifer, A F Stewart, Terence Wu, William M. Philbrick, Katherine E. Dee, A E Broadus, William J. Burtis, L.M. Milstone, L M Matovcik, Karl L. Insogna
Publikováno v: Journal of Biological Chemistry. 267:18236-18243
The cDNA-predicted amino acid sequence of parathyroid hormone-related protein (PTHrP) contains multiple basic amino acid motifs, suggesting that PTHrP undergoes extensive post-translational processing prior to secretion. The secretory forms of the pe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7e84a9b21e1578a5a871562bd012ea6
https://doi.org/10.1016/s0021-9258(19)37178-9
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10
Immunochemical Characterization of Circulating Parathyroid Hormone–Related Protein in Patients with Humoral Hypercalcemia of Cancer
Autor: Andrew F. Stewart, Terence Wu, Arthur E. Broadus, Maryann Mitnick, William J. Burtis, John J. Orloff, Thomas G. Brady, Raymond P. Warrell, Beatriz R. Olson, Julie B. Ersbak
Publikováno v: New England Journal of Medicine. 322:1106-1112
Tumors from patients with humoral hypercalcemia of cancer produce a parathyroid hormone-related protein (PTHRP). We have developed two region-specific immunoassays capable of measuring PTHRP in plasma: an immunoradiometric assay directed toward PTHRP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937a8d39ee4ffe3876f5d54d8915be86
https://doi.org/10.1056/nejm199004193221603
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