Zobrazeno 1 - 10
of 169
pro vyhledávání: '"William J. Bowers"'
Autor:
Amber L. Southwell, Sonia Franciosi, Erika B. Villanueva, Yuanyun Xie, Laurie A. Winter, Janaki Veeraraghavan, Alan Jonason, Boguslaw Felczak, Weining Zhang, Vlad Kovalik, Sabine Waltl, George Hall, Mahmoud A. Pouladi, Ernest S. Smith, William J. Bowers, Maurice Zauderer, Michael R. Hayden
Publikováno v:
Neurobiology of Disease, Vol 76, Iss , Pp 46-56 (2015)
Huntington disease (HD) is an inherited, fatal neurodegenerative disease with no disease-modifying therapy currently available. In addition to characteristic motor deficits and atrophy of the caudate nucleus, signature hallmarks of HD include behavio
Externí odkaz:
https://doaj.org/article/99a93dc1282c4cf6b5dc56f2438c4a79
Autor:
Ernest S. Smith, Alan Jonason, Christine Reilly, Janaki Veeraraghavan, Terrence Fisher, Michael Doherty, Ekaterina Klimatcheva, Crystal Mallow, Chad Cornelius, John E. Leonard, Nicola Marchi, Damir Janigro, Azeb Tadesse Argaw, Trinh Pham, Jennifer Seils, Holm Bussler, Sebold Torno, Renee Kirk, Alan Howell, Elizabeth E. Evans, Mark Paris, William J. Bowers, Gareth John, Maurice Zauderer
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 254-268 (2015)
Multiple sclerosis (MS) is a chronic neuroinflammatory disease characterized by immune cell infiltration of CNS, blood–brain barrier (BBB) breakdown, localized myelin destruction, and progressive neuronal degeneration. There exists a significant ne
Externí odkaz:
https://doaj.org/article/9200aa0f032041e08e2248710c9d6c10
Autor:
Suresh de Silva, William J. Bowers
Publikováno v:
Viruses, Vol 1, Iss 3, Pp 594-629 (2009)
Since its emergence onto the gene therapy scene nearly 25 years ago, the replication-defective Herpes Simplex Virus Type-1 (HSV-1) amplicon has gained significance as a versatile gene transfer platform due to its extensive transgene capacity, widespr
Externí odkaz:
https://doaj.org/article/bc205445a63b446cbd5d300abefc0468
Autor:
Maurice Zauderer, Ernest S. Smith, Mark Paris, William J. Bowers, Terrence L. Fisher, Katya Klimatcheva, Maria Scrivens, Susan Giralico, Alan Howell, Renee Kirk, Crystal Mallow, Laurie A. Winter, Jennifer Seils, Michael A. Doherty, Christine Reilly, Janaki Veeraraghavan, Sebold Torno, Holm Bussler, Alan S. Jonason, Elizabeth E. Evans
Analysis and statistics for tumor growth, survival and CR: Immunohistochemistry methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7f9c6525bdc53d65ad79007e8f1a18
https://doi.org/10.1158/2326-6066.22538348
https://doi.org/10.1158/2326-6066.22538348
Autor:
Maurice Zauderer, Ernest S. Smith, Mark Paris, William J. Bowers, Terrence L. Fisher, Katya Klimatcheva, Maria Scrivens, Susan Giralico, Alan Howell, Renee Kirk, Crystal Mallow, Laurie A. Winter, Jennifer Seils, Michael A. Doherty, Christine Reilly, Janaki Veeraraghavan, Sebold Torno, Holm Bussler, Alan S. Jonason, Elizabeth E. Evans
Supplementary Figure S1: SEMA4D and PLXNB1 are highly expressed in human cancer. Supplementary Figure S2: SEMA4D gradient at tumor leading edge. Supplementary Figure S3: Tumor volumes of mice selected for immune cell characterization and functional a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3e741fdd3c1064046f9b7911f212d3
https://doi.org/10.1158/2326-6066.22538351.v1
https://doi.org/10.1158/2326-6066.22538351.v1
Autor:
Maurice Zauderer, Ernest S. Smith, Mark Paris, William J. Bowers, Terrence L. Fisher, Katya Klimatcheva, Maria Scrivens, Susan Giralico, Alan Howell, Renee Kirk, Crystal Mallow, Laurie A. Winter, Jennifer Seils, Michael A. Doherty, Christine Reilly, Janaki Veeraraghavan, Sebold Torno, Holm Bussler, Alan S. Jonason, Elizabeth E. Evans
Semaphorin 4D (SEMA4D, CD100) and its receptor plexin-B1 (PLXNB1) are broadly expressed in murine and human tumors, and their expression has been shown to correlate with invasive disease in several human tumors. SEMA4D normally functions to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f46dcb34992473e0cbb195d9773fa727
https://doi.org/10.1158/2326-6066.c.6548750.v1
https://doi.org/10.1158/2326-6066.c.6548750.v1
Autor:
Joseph D. Rosenblatt, Khaled A. Tolba, Howard J. Federoff, Eckhard R. Podack, Dien G. Pham, Yu Zhang, Gail R. Walker, William J. Bowers, Hovav Nechushtan, Kyung H. Yi
Supplementary Figure 1 from Adoptively Transferred Tumor-Specific T Cells Stimulated Ex vivo Using Herpes Simplex Virus Amplicons Encoding 4-1BBL Persist in the Host and Show Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e43db2119c4d9e19005a3e07ee5087
https://doi.org/10.1158/0008-5472.22365674
https://doi.org/10.1158/0008-5472.22365674
Autor:
Joseph D. Rosenblatt, Khaled A. Tolba, Howard J. Federoff, Eckhard R. Podack, Dien G. Pham, Yu Zhang, Gail R. Walker, William J. Bowers, Hovav Nechushtan, Kyung H. Yi
Supplementary Figure 2 Legend from Adoptively Transferred Tumor-Specific T Cells Stimulated Ex vivo Using Herpes Simplex Virus Amplicons Encoding 4-1BBL Persist in the Host and Show Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942d7d47a1c1ffaa90f8f689b56db76c
https://doi.org/10.1158/0008-5472.22365671.v1
https://doi.org/10.1158/0008-5472.22365671.v1
Autor:
Joseph D. Rosenblatt, Khaled A. Tolba, Howard J. Federoff, Eckhard R. Podack, Dien G. Pham, Yu Zhang, Gail R. Walker, William J. Bowers, Hovav Nechushtan, Kyung H. Yi
Supplementary Figure 2 from Adoptively Transferred Tumor-Specific T Cells Stimulated Ex vivo Using Herpes Simplex Virus Amplicons Encoding 4-1BBL Persist in the Host and Show Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cfad342852bd2daeaf8507bcd8b890
https://doi.org/10.1158/0008-5472.22365668
https://doi.org/10.1158/0008-5472.22365668
Autor:
Joseph D. Rosenblatt, Khaled A. Tolba, Howard J. Federoff, Eckhard R. Podack, Dien G. Pham, Yu Zhang, Gail R. Walker, William J. Bowers, Hovav Nechushtan, Kyung H. Yi
4-1BB is a T-cell costimulatory receptor which binds its ligand 4-1BBL, resulting in prolonged T cell survival. We studied the antitumor effects of adoptively transferred tumor-specific T cells expanded ex vivo using tumors transduced with herpes sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b6efe79fab67639f140cfef0e74b08
https://doi.org/10.1158/0008-5472.c.6494816
https://doi.org/10.1158/0008-5472.c.6494816