Zobrazeno 1 - 10
of 153
pro vyhledávání: '"William J. Bell"'
The essential volume on cockroach biology and behavior.The cockroach is truly an evolutionary wonder. This definitive volume provides a complete overview of suborder Blattaria, highlighting the diversity of these amazing insects in their natural envi
Autor:
Chiara Falcicchia, Giovanna Paolone, Dwaine F. Emerich, Francesca Lovisari, William J. Bell, Tracie Fradet, Lars U. Wahlberg, Michele Simonato
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 211-224 (2018)
Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated c
Externí odkaz:
https://doaj.org/article/3358439482c54be997637622f1eff5a7
Autor:
Jeffrey H. Kordower, Giovanna Paolone, Lars Wahlberg, William J. Bell, Tracie Fradet, Dwaine F. Emerich
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 1, Iss, Pp 19-29 (2020)
Current Research in Pharmacology and Drug Discovery
Current Research in Pharmacology and Drug Discovery
Delivering glial cell line-derived neurotrophic factor (GDNF) to the brain is a potential treatment for Parkinson's Disease (PD). Here we use an implantable encapsulated cell technology that uses modified human clonal ARPE-19 cells to deliver of G
Autor:
Dwaine F. Emerich, Christopher G. Thanos, Moses Goddard, Stephen J.M. Skinner, Marilyn S. Geany, William J. Bell, Briannan Bintz, Patricia Schneider, Yaping Chu, Rangasamy Suresh Babu, Cesario V. Borlongan, Kim Boekelheide, Susan Hall, Bronwyn Bryant, Jeffrey H. Kordower
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 2, Pp 471-480 (2006)
Huntington's disease (HD) results from degeneration of striatal neurons. Choroid plexus (CP) cells secrete neurotrophic factors, and CP transplants are neuroprotective in rat models of HD. To determine if similar neuroprotective effects could be obta
Externí odkaz:
https://doaj.org/article/783445b7f48e49cfa7aa0b35f236bada
Autor:
Merab Kokaia, Giovanna Paolone, Chiara Falcicchia, Michele Simonato, Lars Wahlberg, Dwaine F. Emerich, Francesca Lovisari, Mario Barbieri, William J. Bell, Tracie Fradet
Publikováno v:
The Journal of Neuroscience. 39:2144-2156
Neurotrophic factors are candidates for treating epilepsy, but their development has been hampered by difficulties in achieving stable and targeted delivery of efficacious concentrations within the desired brain region. We have developed an encapsula
Autor:
Giovanna Paolone, Dwaine F. Emerich, Tracie Fradet, William J. Bell, Michele Simonato, Chiara Falcicchia, Lars Wahlberg, Francesca Lovisari
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 211-224 (2018)
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 211-224 (2018)
Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated c
Autor:
William J. Bell
Publikováno v:
Cockroaches as Models for Neurobiology: Applications in Biomedical Research ISBN: 9781351070751
Cockroaches as Models for Neurobiology: Applications in Biomedical Research
Cockroaches as Models for Neurobiology: Applications in Biomedical Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ada921831db9f6a8aba210a9958c95
https://doi.org/10.1201/9781351070751-2
https://doi.org/10.1201/9781351070751-2
Publikováno v:
Advances in Group Work Research ISBN: 9781315791777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45486cf3be61dac1e5a6e363241a460d
https://doi.org/10.4324/9781315791777-2
https://doi.org/10.4324/9781315791777-2
Autor:
Mark P. Lavoie, Meg Palmatier, Frank T. Gentile, Faith A. Kaplan, Deborah M. Fiore, Tyrone F. Hazlett, William J. Bell, Thomas R. Flanagan PhD
Publikováno v:
Cell Transplantation, Vol 2 (1993)
Two PC12 cell-derived lines have been studied following encapsulation into polymer-based hollow fibers with respect to secreted catecholamines and their metabolites. Cellular encapsulation provides a chronic microperfusion environment within which ba
Externí odkaz:
https://doaj.org/article/f4424975658a41c39d6af1b9c7ad50d2
Autor:
Jebecka Hudak, William J. Bell, Dwaine F. Emerich, Omar Abdel-Rahman Ali, Edward J. Doherty, David J. Mooney, Marie-Therese Laliberte, Tracie Fradet
Publikováno v:
Journal of Controlled Release. 154:249-257
We previously engineered a macroporous, polymer-based vaccine that initially produces GM-CSF gradients to recruit local dendritic cells and subsequently presents CpG oligonucleotides, and tumor lysate to cell infiltrates to induce immune cell activat