Zobrazeno 1 - 10
of 76
pro vyhledávání: '"William J S, Lockley"'
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES.
This paper describes the deuterium-labelling of alkylnitroaromatics by base-catalysed exchange with deuterium oxide. As the alkyl protons alpha to the aromatic ring are the most acidic sites in the molecule, regioselective hydrogen isotope exchange a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087824a964701458b117e99c502193c7
https://pubmed.ncbi.nlm.nih.gov/36453978
https://pubmed.ncbi.nlm.nih.gov/36453978
Autor:
William J. S. Lockley, Paul Trevorrow
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 64:425-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b15ad32f234f86c9aba50751659ea87
https://doi.org/10.1002/jlcr.3936
https://doi.org/10.1002/jlcr.3936
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 65(4)
Base catalysed exchange with sodium hydroxide, calcium oxide or N,N,N,N-tetramethylguanidine in deuterium oxide is a viable procedure for the preparation of terminally deuterated alkynes for those alkynes stable to strong base. The use of silver perc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7cf9318bfb4aff8279b07051071ed7
https://pubmed.ncbi.nlm.nih.gov/35067956
https://pubmed.ncbi.nlm.nih.gov/35067956
Autor:
Edward D. McNaghten, William J. S. Lockley, Ian D. Cunningham, Peter Jenkins, Katerina Ridge, Neil Seagrave
Publikováno v:
Journal of Energetic Materials. 37:188-198
Simulated ageing of 2,4-dinitro-1-ethylbenzene (DNEB) in DMSO in the presence of O2 in a closed system at 85–105°C gave benzylic oxidised products 1-(2,4-dinitrophenyl)ethanol (DNPE) and 2,4-dinitr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af41751a4db30d133f3b2cec278ec99
https://doi.org/10.1080/07370652.2018.1559259
https://doi.org/10.1080/07370652.2018.1559259
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 63(13)
Catalytic dehalogenation of aromatic halides using isotopic hydrogen gas is an important strategy for labelling pharmaceuticals, biochemicals, environmental agents and so forth. To extend, improve and further understand this process, studies have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c3574f3ec3a0f14aaedf2d4b20228be
https://pubmed.ncbi.nlm.nih.gov/32886808
https://pubmed.ncbi.nlm.nih.gov/32886808
Autor:
Adam, Nelson, Robert J, Phipps, Georgie J, Crane, Niccolo A E, Venanzi, William J S, Lockley, Matthew, Tredwell, Niklaas J, Buurma, Andrew, Ballard, Hiwa O, Ahmad, Stefania, Narduolo, Lucy, Rosa, Nikki, Chand, David A, Cosgrove, Peter, Varkonyi, Nabil, Asaad, Simone, Tomasi, Andrew G, Leach, Nick, Summerhill, Jon, Bloom, Mark, Newby, Stephen, Madden, Daniela, Roman, Ruediger M, Exner, Fernando, Cortezon-Tamarit, Haobo, Ge, Stephen, Paisey, Sofia I, Pascu, Rafael T M, de Rosales, Helen C, Hailes, Yu, Wang, Jianxiong, Zhao, Daniel, Méndez-Sánchez, Rebecca, Rodan, Fabiana, Subrizi, Benjamin R, Lichman, Nicholas H, Keep, John M, Ward, Mark, Harris, Martin, Lamb, Vernon, Wilson, Peter, Iafrate, Flaviu, Bulat, Andre A, Néves, Friederike, Hesse, De-En, Hu, Franklin, Aigbirhio, Finian J, Leeper, Kevin M, Brindle, Jack S, Rowbotham, Koji, Urata, Holly A, Reeve, Kylie A, Vincent, Rebekka, Hueting
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::888e0cb67bcb7d60a1f8334b4209196a
https://pubmed.ncbi.nlm.nih.gov/32678462
https://pubmed.ncbi.nlm.nih.gov/32678462
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:136-146
When the isotopic abundance or specific activity of a labeled compound is determined by mass spectrometry (MS), it is necessary to correct the raw MS data to eliminate ion intensity contributions, which arise from the presence of heavy isotopes at na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb8922fbf23299d682cfd1a1a94864e
https://doi.org/10.1002/jlcr.3370
https://doi.org/10.1002/jlcr.3370
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:544-552
Improvements to thin layer chromatography (TLC) analysis can be made easily and cheaply by the application of digital colour photography and image analysis. The combined technique, digitally enhanced TLC (DE-TLC), is applicable to the accurate quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63cce4d51b0af10ba8ab64e4d50ed6f0
https://doi.org/10.1002/jlcr.3052
https://doi.org/10.1002/jlcr.3052
Autor:
William J. S. Lockley
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:417-427
Isotopic chemistry offers the opportunity for organic chemists to explore a surprisingly large variety of scientific avenues. It lends itself naturally to multidisciplinary research projects and provides the sophisticated tools with which the most co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d461b6b275fa9a87330bfa6fb905a6e
https://doi.org/10.1002/jlcr.3045
https://doi.org/10.1002/jlcr.3045
Autor:
Erik Årstad, Adam Badar, Andrew Baxter, John F. Bower, Karl M. Cable, Michael A. Carroll, Melanie Y. T. Chan, Michael Charlton, Martin Christlieb, Bart Cornelissen, Liam R. Cox, Ben Davis, Jonathan R. Dilworth, Ethaar El-Emir, George J. Ellames, Eva Galante, Neil Geach, Antony D. Gee, Véronique Gouverneur, Thomas J. Gregson, David Hendry, Rebekka Hueting, Kamila Hussien, Tenzeela Ilyas, Daniel D. Jenkins, Veerle Kersemans, Eric Knagg, Matthias Koepp, Andrew D. Kohler, Joel A. Krauser, Guillaume G. Launay, William J. S. Lockley, Mark F. Lythgoe, Daniel P. Manthorpe, Andrew McEwen, Ruth J. Muschel, Mark F. Oldfield, Jan Passchier, R. Barbara Pedley, Vineeth Rajkumar, Christopher D. Reed, Mathew Robson, Stephen J. Roe, Jim J. Ryan, Kerstin Sander, Nick Shipley, Sean C. Smart, Neil Smith, Daniel W. Spurr, Keith R. Taylor, Matthew Tredwell, David M. Whitehead, Geoffrey Woolley, Ran Yan
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:50-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2678f0102323fdd2d061d239eba19777
https://doi.org/10.1002/jlcr.3015
https://doi.org/10.1002/jlcr.3015