Zobrazeno 1 - 10
of 259
pro vyhledávání: '"William J Roberts"'
Autor:
Li Zuo, Philip T Diaz, Michael T Chien, William J Roberts, Juliana Kishek, Thomas M Best, Peter D Wagner
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109884 (2014)
Prolonged muscle exposure to low PO2 conditions may cause oxidative stress resulting in severe muscular injuries. We hypothesize that PO2 cycling preconditioning, which involves brief cycles of diaphragmatic muscle exposure to a low oxygen level (40
Externí odkaz:
https://doaj.org/article/1a7a647cc8ff41ef942d74b7e0c4ada3
Publikováno v:
American Journal of Hypertension. 27:643-650
Hypertension, commonly recognized as high blood pressure, is a serious disease that affects millions of people worldwide. Similar to many physiological disorders, hypertension consists of several different cellular signaling pathways that involve var
Publikováno v:
Frontiers in Biology. 8:377-386
The common cold is most often a result of human rhinovirus (HRV) infection. Common cold symptoms including rhinorrhea and nasal obstruction frequently occur during HRV infection of the upper respiratory tract. Conversely, HRV may also infect the epit
Publikováno v:
Frontiers in Biology. 8:305-311
Oxidative stress can cause extensive damage to cardiac tissue under reperfusion conditions. However, preconditioning the myocardium may diminish these negative effects and alleviate reperfusion injury. There are a variety of preconditioning therapies
Autor:
Irving Granet, William J. Roberts
Publikováno v:
Journal of the American Society for Naval Engineers. 68:591-594
Autor:
William J. Roberts, Kenneth B. Sloan
Publikováno v:
Journal of Pharmaceutical Sciences. 92:1028-1036
The 3-alkylcarbonyloxymethyl-5-fluorouracil (3-ACOM-5-FU) prodrugs have been characterized by their solubilities in isopropyl myristate (S(IPM)) and partition coefficients between IPM and pH 4.0 buffer (K(IPM:AQ)). Estimated S(AQ) values have been ob
Publikováno v:
The Journal of Pain. 3:181-189
The formalin test is commonly used as a model of persistent pain. Besides producing pain behavior, hind paw formalin injection induces the expression of the immediate-early gene, c- fos . A current controversy is whether noxious stimulus-induced Fos
Publikováno v:
Journal of Visualized Experiments.
Function analysis of rodent respiratory skeletal muscles, particularly the diaphragm, is commonly performed by isolating muscle strips using invasive surgical procedures. Although this is an effective method of assessing in vitro diaphragm activity,
Autor:
William J. Roberts, Kenneth B. Sloan
Publikováno v:
Journal of Pharmaceutical Sciences. 90:1318-1323
Data developed by Wenkers and Lippold for the flux of 10 nonsteroidal anti‐inflammatory drugs from light mineral oil (MO) through human skin in vivo has been analyzed using the transformed Potts–Guy equation. The analysis shows that the flux is d
Autor:
William J. Roberts, Kenneth B. Sloan
Publikováno v:
Journal of Pharmaceutical Sciences. 89:1415-1431
Multiple regression analysis of fluxes from suspensions in isopropyl myristate (J(M)) as a function of molecular weights (MW) and solubilities in isopropyl myristate (S(IPM)) and water (S(AQ)) were performed on a data set of 41 compounds (n = 41) com