Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William J Melvin"'
Autor:
Sonya J. Wolf, Christopher O. Audu, Amrita Joshi, Aaron denDekker, William J. Melvin, Frank M. Davis, Xianying Xing, Rachael Wasikowski, Lam C. Tsoi, Steven L. Kunkel, Johann E. Gudjonsson, Mary X. O’Riordan, J. Michelle Kahlenberg, Katherine A. Gallagher
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Wound repair following acute injury requires a coordinated inflammatory response. Type I IFN signaling is important for regulating the inflammatory response after skin injury. IFN-κ, a type I IFN, has recently been found to drive skin inflammation i
Externí odkaz:
https://doaj.org/article/eca6cf178c67407eb93d2292893b3a0c
Autor:
William J. Melvin, Christopher Audu, Emily Barrett, Amrita Joshi, Kevin Mangum, Sonya Wolf, Sriganesh Sharma, Andrea T. Obi, Bethany Moore, Katherine Gallagher
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 406- (2022)
Externí odkaz:
https://doaj.org/article/3a8c517681d64016baf56b6454e4e407
Autor:
Sriganesh B. Sharma, William J. Melvin, Christopher O. Audu, Yogendra Kanthi, Jason S. Knight, Nicole Rhoads, Reheman Adili, Michael A. Holinstat, Bethany B. Moore, Peter K. Henke, Thomas W. Wakefield, Katherine A. Gallagher, Andrea T. Obi
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 403-404 (2022)
Externí odkaz:
https://doaj.org/article/d97de6c790394ed0a325863032b6bf3a
Autor:
Frank M. Davis, Lam C. Tsoi, Rachael Wasikowski, Aaron denDekker, Amrita Joshi, Carol Wilke, Hongping Deng, Sonya Wolf, Andrea Obi, Steven Huang, Allison C. Billi, Scott Robinson, Jay Lipinski, William J. Melvin, Christopher O. Audu, Stephan Weidinger, Steven L. Kunkel, Andrew Smith, Johann E. Gudjonsson, Bethany B. Moore, Katherine A. Gallagher
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigeneti
Externí odkaz:
https://doaj.org/article/f96a2c186aa440dc9e0a0bd22363cca4
Autor:
Sriganesh B. Sharma, William J. Melvin, Christopher O. Audu, Monica Bame, Nicole Rhoads, Weisheng Wu, Yogendra Kanthi, Jason S. Knight, Reheman Adili, Michael A. Holinstat, Thomas W. Wakefield, Peter K. Henke, Bethany B. Moore, Katherine A. Gallagher, Andrea T. Obi
Coronavirus-associated coagulopathy (CAC) is a morbid and lethal sequela of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CAC results from a perturbed balance between coagulation and fibrinolysis and occurs in conjunction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7897c43b4a7ea69e746059941dee64c
Publikováno v:
Semin Cell Dev Biol
Non-healing wounds in Type 2 Diabetes (T2D) patients represent the most common cause of amputation in the US, with an associated 5-year mortality of nearly 50%. Our lab has examined tissue from both T2D murine models and human wounds in order to expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba250e310cdc3e6f7bbb74918559a530
https://doi.org/10.1016/j.semcdb.2021.06.013
https://doi.org/10.1016/j.semcdb.2021.06.013
Autor:
William J. Melvin, Temet M. McMichael, Nicholas M. Chesarino, Jocelyn C. Hach, Jacob S. Yount
Publikováno v:
Viruses, Vol 7, Iss 6, Pp 3035-3052 (2015)
Interferon induced transmembrane proteins (IFITMs) found in vertebrates restrict infections by specific viruses. IFITM3 is known to be essential for restriction of influenza virus infections in both mice and humans. Vertebrate IFITMs are hypothesized
Externí odkaz:
https://doaj.org/article/e62ec6d78e9c44e099984b11ea46bf6a
Autor:
Sriganesh B Sharma, William J Melvin, Christopher O Audu, Yogendra Kanthi, Jason S Knight, Nicole Rhoads, Reheman Adili, Michael A Holinstat, Bethany B Moore, Peter K Henke, Thomas W Wakefield, Katherine A Gallagher, Andrea T Obi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Objectives: Coronavirus associated coagulopathy (CAC) is postulated to be driven by systemic macrophage activation after SARS-CoV-2 infection and presents with elevated risk of thrombogenesis and hyperfibrinolysis. Previous work shows that the histon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa61a46ac9292f7c894f2198e4bbb66d
https://doi.org/10.1161/atvb.42.suppl_1.114
https://doi.org/10.1161/atvb.42.suppl_1.114
Autor:
Christopher O. Audu, William J. Melvin, Amrita D. Joshi, Sonya J. Wolf, Jadie Y. Moon, Frank M. Davis, Emily C. Barrett, Kevin D. Mangum, Hongping Deng, Xianying Xing, Rachel Wasikowski, Lam C. Tsoi, Sriganesh B. Sharma, Tyler M. Bauer, James Shadiow, Matthew A. Corriere, Andrea T. Obi, Steven L. Kunkel, Benjamin Levi, Bethany B. Moore, Johann E. Gudjonsson, Andrew M. Smith, Katherine A. Gallagher
Publikováno v:
Cellularmolecular immunology. 19(11)
Macrophage plasticity is critical for normal tissue repair following injury. In pathologic states such as diabetes, macrophage plasticity is impaired, and macrophages remain in a persistent proinflammatory state; however, the reasons for this are unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50a0bdf81ae81a60c47d1b08236e311
https://pubmed.ncbi.nlm.nih.gov/36127466
https://pubmed.ncbi.nlm.nih.gov/36127466
Autor:
Hongping Deng, Christian J. Konopka, Suma Prabhu, Suresh Sarkar, Natalia Gonzalez Medina, Muhammad Fayyaz, Opeyemi H. Arogundade, Hashni Epa Vidana Gamage, Sayyed Hamed Shahoei, Duncan Nall, Yeoan Youn, Iwona T. Dobrucka, Christopher O. Audu, Amrita Joshi, William J. Melvin, Katherine A. Gallagher, Paul R. Selvin, Erik R. Nelson, Lawrence W. Dobrucki, Kelly S. Swanson, Andrew M. Smith
Publikováno v:
ACS Nano
Macrophages are white blood cells with diverse functions contributing to a healthy immune response as well as the pathogenesis of cancer, osteoarthritis, atherosclerosis, and obesity. Due to their pleiotropic and dynamic nature, tools for imaging and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f0d671f490b7012630a5be0a8428b6
https://europepmc.org/articles/PMC8900655/
https://europepmc.org/articles/PMC8900655/