Zobrazeno 1 - 10
of 25
pro vyhledávání: '"William J Korzun"'
Autor:
Jody A Rule, Linda S Hynan, Nahid Attar, Corron Sanders, William J Korzun, William M Lee, Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138566 (2015)
Because acute liver failure (ALF) patients share many clinical features with severe sepsis and septic shock, identifying bacterial infection clinically in ALF patients is challenging. Procalcitonin (PCT) has proven to be a useful marker in detecting
Externí odkaz:
https://doaj.org/article/ea3505d02f6a450c88059ff83b6cac18
Autor:
Jennifer D Sisler, Magdalena Morgan, Vidisha Raje, Rebecca C Grande, Marta Derecka, Jeremy Meier, Marc Cantwell, Karol Szczepanek, William J Korzun, Edward J Lesnefsky, Thurl E Harris, Colleen M Croniger, Andrew C Larner
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144444 (2015)
The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes that mediate the antiviral, the antigrowth, and immune surveillance effects of interferons an
Externí odkaz:
https://doaj.org/article/10a097becac749e9bfee43712bf8bf5b
Autor:
Siddhartha S. Ghosh, Shobha Ghosh, Paul J. Yannie, Yashnoor K Sandhu, Jing Wang, William J. Korzun
Publikováno v:
The Journal of Nutrition. 150:285-293
BACKGROUND A Western-type diet (WD), rich in fat and cholesterol but deficient in fiber, induces development of diabetes and atherosclerosis. Colonic bacteria use the gut's mucous lining as an alternate energy source during periods of fiber deficienc
Autor:
Carrol R. Nanco, Kaitlin L Pierce, William J Korzun, Carl E. Wolf, Brett L Goldfine, Justin L. Poklis
Publikováno v:
J Anal Toxicol
Opioid usage in the USA has increased over the past decade, with prescriptions increasing from 76 million in 1991 to 207 million in 2013. New regulations have curbed the number of prescriptions, leading to an increase in heroin use. Heroin-related ov
Autor:
Jing Wang, Yashnoor K. Sandhu, William J. Korzun, Genta Kakiyama, Shobha Ghosh, Siddhartha S. Ghosh, Remy C. Cooper, Paul J. Yannie
Publikováno v:
Circ Res
Rationale: Intestinal alkaline phosphatase (IAP) is secreted by enterocytes and is present on the apical surface. It not only detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen and limits intestinal inflammation but also restric
Publikováno v:
Biomaterials
Reduction of lipoprotein uptake by macrophages and stimulation of cholesterol efflux are two essential steps required for atherosclerotic plaque regression. We used the optimized mannose-functionalized dendrimeric nanoparticle (mDNP)-based platform f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd51af3c6c3500a3b57dfdb994d28e6
https://europepmc.org/articles/PMC7530139/
https://europepmc.org/articles/PMC7530139/
Autor:
William J. Korzun, Michele Zitzmann, Lisa Perkins, Payman Nasr, Cecelia Landin, Lisa H. Hochstein, Tiffany Gill, Lindsay Gilbert, Vivian Annette Lind, Nancy Calder, Reed Brooks, Letycia Nunez-Argote, Karen Hunter, Catherine Smith, Jeremiah Barrett, Cheryl Jackson-Harris, Melissa Jamerson, Angela Foley, Tina Gunaldo, Mitzi Glover, Dayanjan S. Wijesinghe, Lorin M. Bachmann, Melanie Juba
Publikováno v:
American Society for Clinical Laboratory Science. 30:87-91
Autor:
Hongliang He, William J. Korzun, Jing Wang, Shobha Ghosh, Chunqing Guo, Hu Yang, Xiang-Yang Wang
Publikováno v:
Nano letters. 18(10)
Cell membrane-camouflaged nanoparticles have appeared as a promising platform to develop active tumor targeting nanomedicines. To evade the immune surveillance, we designed a composite cell membrane-camouflaged biomimetic nanoplatform, namely, leutus
Sterol carrier protein-2 deficiency attenuates diet-induced dyslipidemia and atherosclerosis in mice
Intracellular cholesterol transport proteins move cholesterol to different subcellular compartments and thereby regulate its final metabolic fate. In hepatocytes, for example, delivery of high-density lipoprotein (HDL)–associated cholesterol for bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a32c9eef5507c38de91747ce44ff9e
https://europepmc.org/articles/PMC6005425/
https://europepmc.org/articles/PMC6005425/
Autor:
Katsuyuki Nakajima, Ikunosuke Sakurabayashi, Lorin M. Bachmann, Masakazu Nakamura, Göran Nilsson, Gary L. Myers, Alan T. Remaley, William J. Korzun, W. Greg Miller, Robert D. Shamburek
Publikováno v:
Clinical Chemistry. 61:1107-1113
BACKGROUND We used a difference in bias approach to evaluate the commutability of 4 frozen serum pools for 8 direct methods for measurement of HDL and LDL cholesterol (HDLC and LDLC). METHODS Freshly collected nonfrozen sera from 138 diseased and 37