Zobrazeno 1 - 10
of 40
pro vyhledávání: '"William J Godinez"'
Autor:
Barbara Di Ventura, Benoît Knecht, Helena Andreas, William J Godinez, Miriam Fritsche, Karl Rohr, Walter Nickel, Dieter W Heermann, Victor Sourjik
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-12 (2013)
Abstract The mechanisms underlying chromosome segregation in prokaryotes remain a subject of debate and no unifying view has yet emerged. Given that the initial disentanglement of duplicated chromosomes could be achieved by purely entropic forces, ev
Externí odkaz:
https://doaj.org/article/ba0759c53c7c4953a054b5ae1e63b6ee
Autor:
Sergey Ivanchenko, William J Godinez, Marko Lampe, Hans-Georg Kräusslich, Roland Eils, Karl Rohr, Christoph Bräuchle, Barbara Müller, Don C Lamb
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000652 (2009)
Assembly and release of human immunodeficiency virus (HIV) occur at the plasma membrane of infected cells and are driven by the Gag polyprotein. Previous studies analyzed viral morphogenesis using biochemical methods and static images, while dynamic
Externí odkaz:
https://doaj.org/article/3aaeffe7c9b945ddbd33de394217df29
Autor:
Andrea Imle, Peter Kumberger, Nikolas D. Schnellbächer, Jana Fehr, Paola Carrillo-Bustamante, Janez Ales, Philip Schmidt, Christian Ritter, William J. Godinez, Barbara Müller, Karl Rohr, Fred A. Hamprecht, Ulrich S. Schwarz, Frederik Graw, Oliver T. Fackler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Here, using an integrative experimental and computational approach, Imle et al. show how cell motility and density affect HIV cell-associated transmission in a three-dimensional tissue-like culture system of CD4+ T cells and collagen, and how differe
Externí odkaz:
https://doaj.org/article/9b883324a99d4e44ab53be00321fd321
Autor:
Delia Bucher, Felix Frey, Kem A. Sochacki, Susann Kummer, Jan-Philip Bergeest, William J. Godinez, Hans-Georg Kräusslich, Karl Rohr, Justin W. Taraska, Ulrich S. Schwarz, Steeve Boulant
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of
Externí odkaz:
https://doaj.org/article/3f0780a0131e44ce8d01e1cb3d81a9e5
Autor:
Marc A. Coram, Lisha Wang, William J. Godinez, David T. Barkan, Zan Armstrong, D. Michael Ando, Brian Y. Feng
Publikováno v:
ACS infectious diseases. 8(1)
Combination therapies are common in many therapeutic contexts, including infectious diseases and cancer. A common approach for evaluating combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72298692d3a3ae4352df95e3e2f916fe
https://pubmed.ncbi.nlm.nih.gov/34937332
https://pubmed.ncbi.nlm.nih.gov/34937332
Autor:
Michal Pikusa, Olivier René, Sarah Williams, Yen-Liang Chen, Eric Martin, William J. Godinez, Srinivasa P S Rao, W. Armand Guiguemde, Florian Nigsch
Designing novel molecules with targeted biological activities and optimized physicochemical properties is a challenging endeavor in drug discovery. Recent developments in artificial intelligence have enhanced the early steps of de novo drug design an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1fae6e9e95846835886d45388f83b83
https://doi.org/10.1101/2021.12.10.472084
https://doi.org/10.1101/2021.12.10.472084
Autor:
Robert Lowell Simmons, Helen Chan, William J. Godinez, Dita M. Rasper, Imtiaz Hossain, Srijan Ranjitkar, Cindy Li, Brian Y. Feng, Xian Zhang
Beta-lactam antibiotics comprise one of the earliest known classes of antibiotic therapies. These molsecules covalently inhibit enzymes from the family of penicillin-binding proteins, which are essential to the construction of the bacterial cell wall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952e9b250d8acb775ccf88cd1be69e06
https://doi.org/10.1101/545335
https://doi.org/10.1101/545335
Autor:
Xian Zhang, Sun Choi, Imtiaz Hossain, Vikram A. Saletore, William J. Godinez, Kushal Datta, Kyle H. Ambert
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783030343552
ISC Workshops
ISC Workshops
Existing approaches to train neural networks that use large images require to either crop or down-sample data during pre-processing, use small batch sizes, or split the model across devices mainly due to the prohibitively limited memory capacity avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::196572aed06dec48de578506cc454424
https://doi.org/10.1007/978-3-030-34356-9_35
https://doi.org/10.1007/978-3-030-34356-9_35
Large-scale cellular imaging and phenotyping is a widely adopted strategy for understanding biological systems and chemical perturbations. Quantitative analysis of cellular images for identifying phenotypic changes is a key challenge within this stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39b3d31167460cdef6fa9d329d4a168
Publikováno v:
IEEE Transactions on Image Processing. 24:4122-4136
Automatic fluorescent particle tracking is an essential task to study the dynamics of a large number of biological structures at a sub-cellular level. We have developed a probabilistic particle tracking approach based on multi-scale detection and two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f3d5049b81e8257f8e684e22736317
https://doi.org/10.1109/tip.2015.2458174
https://doi.org/10.1109/tip.2015.2458174