Zobrazeno 1 - 10
of 300
pro vyhledávání: '"William J Burlingham"'
Autor:
William J. Burlingham, PhD, Ewa Jankowska-Gan, MS, John H. Fechner, MS, Christopher J. Little, MD, Jianxin Wang, PhD, Seungpyo Hong, PhD, Miraf Molla, BS, Jeremy A. Sullivan, PhD, David P. Foley, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 6, p e1475 (2023)
Background. Here we test the hypothesis that, like CD81-associated “latent” IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A repetitions predominant (GARP) complex was also tethered to small extracellul
Externí odkaz:
https://doaj.org/article/55c62bbd8b1e4c159f6be1fe92b81bef
Autor:
Jue Zhang, Brian E. McIntosh, Bowen Wang, Matthew E. Brown, Mitchell D. Probasco, Sarah Webster, Bret Duffin, Ying Zhou, Lian-Wang Guo, William J. Burlingham, Craig Kent, Michael Ferris, James A. Thomson
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1269-1281 (2019)
Summary: Contractile to synthetic phenotypic switching of smooth muscle cells (SMCs) contributes to stenosis in vascular disease and vascular transplants. To generate more contractile SMCs, we performed a high-throughput differentiation screen using
Externí odkaz:
https://doaj.org/article/a6646e7a3e204df7957e528997a5ae08
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://doaj.org/article/440bd605fad843e1bb8e3d2b1e36fbab
Autor:
Jeremy A. Sullivan, David P. AlAdra, Brian M. Olson, Douglas G. McNeel, William J. Burlingham
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Originally identified as lymphocyte regulation of fellow lymphocytes, our understanding of infectious tolerance has undergone significant evolutions in understanding since being proposed in the early 1970s by Gershon and Kondo and expanded upon by He
Externí odkaz:
https://doaj.org/article/9bd64808cfef4ef380e337f25657c867
Autor:
Jeremy A. Sullivan, Yusuke Tomita, Ewa Jankowska-Gan, Diego A. Lema, Matt P. Arvedson, Ashita Nair, William Bracamonte-Baran, Ying Zhou, Kristy K. Meyer, Weixiong Zhong, Deepali V. Sawant, Andrea L. Szymczak-Workman, Qianxia Zhang, Creg J. Workman, Seungpyo Hong, Dario A.A. Vignali, William J. Burlingham
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1039-1051.e5 (2020)
Summary: Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 assume and its role in peripheral tolerance remain elusive. We induce
Externí odkaz:
https://doaj.org/article/19bc2a5483074d60bb874b0ead25e86d
Autor:
Matthew E. Brown, Ying Zhou, Brian E. McIntosh, Ian G. Norman, Hannah E. Lou, Mitch Biermann, Jeremy A. Sullivan, Timothy J. Kamp, James A. Thomson, Petros V. Anagnostopoulos, William J. Burlingham
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1175-1183 (2018)
Summary: Here, we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus and umbilical cord blood hematopoietic stem cells (HSCs). Conventional humanized mouse models are made by engrafti
Externí odkaz:
https://doaj.org/article/081f57c2cd484249a05a76cb93c1caa6
Autor:
William J. Burlingham
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/6b71bc8c5b8e491e8ca8551b9c28f937
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Cell based therapies have been studied extensively in the context of transplantation tolerance induction. The most successful protocols have relied on transfusion of bone marrow prior to the transplantation of a renal allograft. However, it is not cl
Externí odkaz:
https://doaj.org/article/8cc54f6796ab49bbb6376cd41dd0e130
Autor:
William J. Burlingham, Bret M Verhoven, Sarah E. Panzer, Lei Shi, Robert R. Redfield, Weixiong Zhong, Xiang Ding, Shannon R. Reese, Arjang Djamali, Nancy A. Wilson, Loren C. Denlinger
Publikováno v:
Kidney360
Background: Extracellular adenosine triphosphate (ATP) binds to purinergic receptors and promotes inflammatory responses. We tested whether oxidized ATP (oATP), P2X7 receptor antagonist can attenuate acute kidney allograft rejection. Methods: Brown N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b949f1f39da915625de3636af4578f59
https://doi.org/10.34067/kid.0000692019
https://doi.org/10.34067/kid.0000692019
Autor:
Yolanda Ponstein, Luis A. Fernandez, Juan S. Danobeitia, Peter J. Chlebeck, Erzsebet Polyak, Jose R. Torrealba, Casi L. Blanton, Yücel Yankol, Megan L. Springer, Michael J. Eerhart, Jeremy A. Sullivan, Saverio Capuano, Jose A. Reyes, Jennifer Coonen, Myron A. Pozniak, Laura J. Zitur, Anthony M. D'Alessandro, Weixiong Zhong, Edwin Van Amersfoort, William J. Burlingham, Cees van Kooten
Publikováno v:
Transplantation
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Background: Complement activation in kidney transplantation is implicated in the pathogenesis of delayed graft function (DGF). This study evaluated the therapeutic efficacy of high-dose recombinant human C1 esterase inhibitor (rhC1INH) to prevent DGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeda53f63c1477d0615d8ab46b90c68
https://pubmed.ncbi.nlm.nih.gov/34905763
https://pubmed.ncbi.nlm.nih.gov/34905763