Výsledky vyhledávání - "William J Bowers"

Akademický článek

CD4+ T cell effects on CD8+ T cell location defined using bioluminescence.

Autor: Mitra Azadniv, William J Bowers, David J Topham, Ian N Crispe

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16222 (2011)

T lymphocytes of the CD8+ class are critical in delivering cytotoxic function and in controlling viral and intracellular infections. These cells are "helped" by T lymphocytes of the CD4+ class, which facilitate their activation, clonal expansion, ful

Externí odkaz: https://doaj.org/article/06f4d51fc67b4e74a6c0fbd1d4b82fc6

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Akademický článek

GTPase activity plays a key role in the pathobiology of LRRK2.

Autor: Yulan Xiong, Candice E Coombes, Austin Kilaru, Xiaojie Li, Aaron D Gitler, William J Bowers, Valina L Dawson, Ted M Dawson, Darren J Moore

Publikováno v: PLoS Genetics, Vol 6, Iss 4, p e1000902 (2010)

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are associated with late-onset, autosomal-dominant, familial Parkinson's disease (PD) and also contribute to sporadic disease. The LRRK2 gene encodes a large protein with multiple domains, in

Externí odkaz: https://doaj.org/article/906284d1bfff43cbae496392727765d6

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