Zobrazeno 1 - 10
of 139
pro vyhledávání: '"William J, Weiss"'
Autor:
Emmanuelle Gras, Trang T. T. Vu, Nhu T. Q. Nguyen, Vuvi G. Tran, Yanjie Mao, Nguyen D. Tran, Nam H. Mai, Oliver X. Dong, David H. Jung, Natalia L. P. P. Iorio, Helvecio C. C. Povoa, Marcos Gabriel Pinheiro, Fabio Aguiar-Alves, William J. Weiss, Bo Zheng, Lily I. Cheng, Charles K. Stover, Bret R. Sellman, Antonio DiGiandomenico, Laure Gibault, Florent Valour, Binh An Diep
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundNew drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumon
Externí odkaz:
https://doaj.org/article/711b678c4c3e47ab9251fd8fcab51201
Publikováno v:
Journal of Investigative Surgery, Vol 32, Iss 8, Pp 706-715 (2019)
Purpose/Aim: In prey species, such as sheep, clinical signs of postoperative pain can manifest in subtle ways or may be concealed entirely. Previous publications describing pain assessment in ruminants focus on lameness and flock behavior, often in a
Externí odkaz:
https://doaj.org/article/36e9c24f8ede4ef1b04bab6c76df3076
Autor:
Gregory P. Howard, Nicole G. Bender, Prachi Khare, Borja López-Gutiérrez, Vincent Nyasembe, William J. Weiss, Jerry W. Simecka, Timothy Hamerly, Hai-Quan Mao, Rhoel R. Dinglasan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A successful malaria transmission blocking vaccine (TBV) requires the induction of a high antibody titer that leads to abrogation of parasite traversal of the mosquito midgut following ingestion of an infectious bloodmeal, thereby blocking the cascad
Externí odkaz:
https://doaj.org/article/b57a063ffd7d4e87aa007842f02ce0da
Autor:
Ray Newswanger, Walter E. Pae, John D. Reibson, Choon Sik Jhun, Heidi Flory, William J. Weiss, Gerson Rosenberg, Jenelle M. Izer, Joshua Cysyk
Publikováno v:
ASAIO Journal. 68:791-799
Current generation continuous flow assist devices to operate at a fixed speed, which limits preload response and exercise capacity in left ventricular assist device (LVAD) patients. A feedback control system was developed to automatically adjust pump
Autor:
Cailin E. Deal, Angelene F. Richards, Tracy Yeung, Max J. Maron, Ziqiu Wang, Yen-Ting Lai, Brian R. Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J. Hsiao, Ivana L. Rajlic, Hillary Koch, Michael Kleyman, Mark E. Pulse, William J. Weiss, Jennifer E. Doering, Samantha K. Lindberg, Nicholas J. Mantis, Andrea Carfi, Obadiah J. Plante
Monoclonal antibody (mAb) therapy is a promising infectious disease intervention strategy but is limited to IgG1 isotypes that have restricted access to mucosal sites. IgA is well-established as the predominant antibody isotype in mucosal secretions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ed2510c7cb21c1a99b7d4f587b5f75
https://doi.org/10.1101/2023.01.03.521487
https://doi.org/10.1101/2023.01.03.521487
Autor:
Cailin Deal, Angelene F. Richards, Tracy Yeung, Max J. Maron, Ziqiu Wang, Yen-Ting Lai, Brian R. Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J. Hsiao, Ivana L. Rajlic, Hillary Koch, Michael Kleyman, Mark E. Pulse, William J. Weiss, Jennifer E. Doering, Samantha K. Lindberg, Nicholas Mantis, Andrea Carfi, Obadiah J. Plante
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cf464e45ecec222f7250343520feeb
https://doi.org/10.2139/ssrn.4423986
https://doi.org/10.2139/ssrn.4423986
Autor:
Choon-Sik Jhun, Lichong Xu, Christopher Siedlecki, Carlo R. Bartoli, Eric Yeager, Branka Lukic, Christopher M. Scheib, Raymond Newswanger, Joshua P. Cysyk, Chan Shen, Karl Bohnenberger, William J. Weiss, Gerson Rosenberg
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992).
The loss of high molecular weight multimers (HMWM) of von Willebrand factor (vWF) in aortic stenosis (AS) and continuous-flow left ventricular assist devices (cf-LVADs) is believed to be associated with high turbulent blood shear. The objective of th
Autor:
Johan A. Kers, Robert E. Sharp, Anthony W. Defusco, Jae H. Park, Jin Xu, Mark E. Pulse, William J. Weiss, Martin Handfield
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Lantibiotics offer an untapped pipeline for the development of novel antibiotics to treat serious Gram-positive (+) infections including Clostridium difficile. Mutacin 1140 (MU1140) is a lantibiotic produced by Streptococcus mutans and acts via a nov
Externí odkaz:
https://doaj.org/article/b817fd7f62a14cda95a6d257a5f10e9a
Autor:
Johan A Kers, Anthony W DeFusco, Jae H Park, Jin Xu, Mark E Pulse, William J Weiss, Martin Handfield
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197467 (2018)
Lantibiotics continue to offer an untapped pipeline for the development of novel antibiotics. We report here the discovery of a novel lantibiotic for the treatment of C. difficile infection (CDI). The leads were selected from a library of over 300 mu
Externí odkaz:
https://doaj.org/article/8576e0e2154a45a69a25cf4db2f4e489
Autor:
William J. Weiss, Christopher J. Burns, Randy W. Jackson, Greg Moeck, Eugen F. Mesaros, Jodie Hamrick, Susan M Cusick, Boyd Steven A, Bin Liu, Denis M. Daigle, Cassandra L Chatwin, Lisa McLaughlin, Kaitlyn John, Daniel C. Pevear, Allison L. Zulli, Robert E. Lee Trout, Luigi Xerri, Mark Pulse
Publikováno v:
Journal of Medicinal Chemistry
A major antimicrobial resistance mechanism in Gram-negative bacteria is the production of β-lactamase enzymes. The increasing emergence of β-lactamase-producing multi-drug-resistant “superbugs” has resulted in increases in costly hospital Emerg