Zobrazeno 1 - 10
of 30
pro vyhledávání: '"William J, Langston"'
Autor:
Maya G. Purisai, Alison L. McCormack, William J. Langston, Louisa C. Johnston, Donato A. Di Monte
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 898-906 (2005)
Changes in the expression of α-synuclein are likely to underlie its normal function as well as its role in pathological processes. The relationship between toxic injury and α-synuclein expression was assessed in the substantia nigra of squirrel mon
Externí odkaz:
https://doaj.org/article/41288431891648e893f52f68f1d8c296
Autor:
Yasuji Matsuoka, Miquel Vila, Sarah Lincoln, Alison McCormack, Melanie Picciano, John LaFrancois, Xin Yu, Dennis Dickson, William J. Langston, Eileen McGowan, Matt Farrer, John Hardy, Karen Duff, Serge Przedborski, Donato A. Di Monte
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 535-539 (2001)
α-Synuclein has been identified as a major component of Lewy body inclusions, which are one of the pathologic hallmarks of idiopathic Parkinson's disease. Mutations in α-synuclein have been found to be responsible for rare familial cases of Parkins
Externí odkaz:
https://doaj.org/article/8e2813da0f1045a4bb948bd73bb938d0
Autor:
Donato A. Di Monte, William J. Langston, Alison L. McCormack, Maya G. Purisai, Louisa C. Johnston
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 898-906 (2005)
Changes in the expression of alpha-synuclein are likely to underlie its normal function as well as its role in pathological processes. The relationship between toxic injury and alpha-synuclein expression was assessed in the substantia nigra of squirr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2596f4fe6b078f42277ac61407dba8f1
https://doi.org/10.1016/j.nbd.2005.05.028
https://doi.org/10.1016/j.nbd.2005.05.028
Publikováno v:
Antioxidants & Redox Signaling. 7:649-653
A loss of nigrostriatal dopaminergic neurons is the primary neurodegenerative feature of Parkinson's disease. Paraquat, a known redox cycling herbicide, has recently been shown to kill selectively nigrostriatal dopaminergic cells in the mouse model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0c0430c09c2eb8a387fb6aaa0ea52b
https://doi.org/10.1089/ars.2005.7.649
https://doi.org/10.1089/ars.2005.7.649
Publikováno v:
Molecular Brain Research. 134:52-56
Mechanisms involved in paraquat neurotoxicity that selectively target nigrostriatal dopaminergic neurons remain relatively unknown. In this study, we tested the hypotheses that paraquat exposure leads to the production of reactive oxygen species (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df805b0822a2ed8ff292961b453b7f4
https://doi.org/10.1016/j.molbrainres.2004.11.005
https://doi.org/10.1016/j.molbrainres.2004.11.005
Autor:
Susana Galante-Oliveira, William J. Langston, Maria E. Pereira, Gary R. Burt, Carlos M. Barroso
Publikováno v:
Applied Organometallic Chemistry. 20:1-4
Nucella lapillus imposex—superimposition of male characters onto prosobranch (a subclass of gastropod molluscs) females—and organotin female body burden were surveyed on the Portuguese coast, from Vila Praia de Âncora (northern limit) to Praia d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d41c46fede49ed13bba5961987ad443f
https://doi.org/10.1002/aoc.1011
https://doi.org/10.1002/aoc.1011
Autor:
William J. Langston, Maria J. Bebianno
Metal Metabolism in Aquatic Environments is a synthesis of recent developments in the field of metal ecotoxicology and features a number of contemporary issues arising from the interaction of metals and biota, such as pathways of assimilation and foo
Publikováno v:
Acta Neuropathologica. 103:599-606
Attempts at classification of fronto-temporal dementias have not yet been completely successful. We report ten cases of sporadic fronto-temporal dementia (FTD) with ubiquitin-positive neuronal inclusions in cortex or in motor neurons in brain stem or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df45ff32a29bbcbf121b3f351a602594
https://doi.org/10.1007/s00401-001-0509-1
https://doi.org/10.1007/s00401-001-0509-1
Publikováno v:
Neurotoxicity Research. 3:537-543
The purpose of this study was to evaluate the possible association between the risk of developing Parkinson’s disease (PD) and exposure to organochlorine pesticides in the mouse model. Animals were treated with a single subcutaneous injection of ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb05aa14851e67f74b28e3dd212fda03
https://doi.org/10.1007/bf03033209
https://doi.org/10.1007/bf03033209
Autor:
John LaFrancois, Alison L. McCormack, Melanie Picciano, Yasuji Matsuoka, Karen Duff, Serge Przedborski, Eileen McGowan, John Hardy, Sarah Lincoln, Miquel Vila, Xin Yu, Dennis W. Dickson, Donato A. Di Monte, William J. Langston, Matthew J. Farrer
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 535-539 (2001)
alpha-Synuclein has been identified as a major component of Lewy body inclusions, which are one of the pathologic hallmarks of idiopathic Parkinson's disease. Mutations in alpha-synuclein have been found to be responsible for rare familial cases of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885f94823b485b84fe8274dcf519eb89
http://www.sciencedirect.com/science/article/pii/S0969996101903924
http://www.sciencedirect.com/science/article/pii/S0969996101903924