Zobrazeno 1 - 10
of 223
pro vyhledávání: '"William J, Kerr"'
Publikováno v:
Chemistry – A European Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e508da0bdcc00c8ba09881813fdcc4
https://doi.org/10.1002/chem.202300403
https://doi.org/10.1002/chem.202300403
Autor:
Jennifer Devlin, William. J. Kerr, David M. Lindsay, Timothy J. D. McCabe, Marc Reid, Tell Tuttle
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 11676-11698 (2015)
Herein we report a combined experimental and theoretical study on the deuterium labelling of benzoate ester derivatives, utilizing our developed iridium N-heterocyclic carbene/phosphine catalysts. A range of benzoate esters were screened, including d
Externí odkaz:
https://doaj.org/article/c5ff85640cc8439ba15f2c120aa01ce5
Publikováno v:
Catalysis Science & Technology. 11:5498-5504
Herein we qualitatively examine the relationship between reaction rate and reaction selectivity in iridium-catalysed hydrogen isotope exchange (HIE) reactions directed by Lewis basic functional groups. We have recently developed a directing group sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd88408cae2aef77cc8058bf8504ed20
https://doi.org/10.1039/d1cy00708d
https://doi.org/10.1039/d1cy00708d
Autor:
Darren L. Poole, William J. Kerr, Blake J. M. Baker, David M. Lindsay, Vipulkumar Kantibhai Patel
Publikováno v:
Green Chemistry. 23:280-287
Described herein is a green, continuous flow process for the synthesis of various aminoimidazoheterocycles, through the Gröebke-Blackburn-Bienaymé reaction (GBBR). This multicomponent procedure combines aminoazines, aldehydes and isocyanides to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c690936156532e05db34bafc455499
https://doi.org/10.1039/d0gc03675g
https://doi.org/10.1039/d0gc03675g
Autor:
Paul Shaw, Storm J. Hassell-Hart, Gayle E. Douglas, Andrew G. Malcolm, Alan R. Kennedy, Gemma V. White, Laura C. Paterson, William J. Kerr
We report here the application of silyl enol ether moieties as efficient alkene coupling partners within cobalt-mediated intramolecular Pauson-Khand reactions. This cyclization strategy delivers synthetically valuable oxygenated cyclopentenone produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af528aeb5cd77acc05de4638b7d9a905
https://strathprints.strath.ac.uk/80138/1/Shaw_etal_OL_2022_Oxygenated_cyclopentenones_via_the_Pauson_Khand_reaction.pdf
https://strathprints.strath.ac.uk/80138/1/Shaw_etal_OL_2022_Oxygenated_cyclopentenones_via_the_Pauson_Khand_reaction.pdf
Publikováno v:
ACS Catalysis
Herein we report the rational, computationally-guided design of an iridium(I) catalyst system capable of enabling directed hy-drogen isotope exchange (HIE) with the challenging sulfone directing group. Substrate binding energy was used as a parame-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f33d5399dd47c1899d9feced1ab5b9
http://europepmc.org/articles/PMC7587147
http://europepmc.org/articles/PMC7587147
Autor:
Scott P. Runyon, Adele.E. Queen, Desong Zhong, David Hesk, David M. Lindsay, William J. Kerr, Timothy R. Fennell, Wayne Mascarella, Kenneth S. Rehder
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 63:196-202
[3 H]Genipin was synthesized in a single step by Ir(I) catalyzed hydrogen isotope exchange. Conditions for selective exchange of the sp2 CH bond ortho to the methyl ester functionality were developed through deuterium modeling studies through a catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0283f6e7cf473fa399212c4113fd94
https://doi.org/10.1002/jlcr.3832
https://doi.org/10.1002/jlcr.3832
Autor:
William J. Kerr, David M. Lindsay
Publikováno v:
Cobalt Catalysis in Organic Synthesis
This chapter provides an overview of recent developments in the Pauson–Khand reaction. The work that is discussed herein is selected from the time period 2013–2018, and only cobalt‐mediated versions of the Pauson–Khand reaction are considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21bef5871719cdb58ae7ea48061dbeb
https://doi.org/10.1002/9783527814855.ch8
https://doi.org/10.1002/9783527814855.ch8
Publikováno v:
Chemical Science
Remote directing groups in a bifunctional molecule do not always behave independently of one another in C–H activation chemistries. A combined DFT and experimental mechanistic study to provide enhanced Ir catalysts for chemoselective C–H deuterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea320dc253a1ed11d8804d9a4fb7925
https://doi.org/10.26434/chemrxiv.13603385.v2
https://doi.org/10.26434/chemrxiv.13603385.v2
A palette of commonly used directing groups, including various pharmaceutically relevant nitrogen-containing heterocycles, are quantitatively ranked based on the results of intermolecular hydrogen isotope exchange competition reactions using two irid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd74647ae1466b5a41da325678e61b9
https://strathprints.strath.ac.uk/73843/1/Timofeeva_etal_CST_2020_A_quantitative_empirical_directing_group_scale_for_selectivity.pdf
https://strathprints.strath.ac.uk/73843/1/Timofeeva_etal_CST_2020_A_quantitative_empirical_directing_group_scale_for_selectivity.pdf