Zobrazeno 1 - 10
of 19
pro vyhledávání: '"William J, Buchser"'
Autor:
Takashi Yurube, William J. Buchser, Zhongying Zhang, Prashanta Silwal, Michael T. Lotze, James D. Kang, Gwendolyn A. Sowa, Nam V. Vo
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Low back pain is a global health problem that originated mainly from intervertebral disc degeneration (IDD). Autophagy, negatively regulated by the phosphatidylinositol 3‐kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) si
Externí odkaz:
https://doaj.org/article/b7cf96995ccc4069bbbcd8d157c03fbb
Autor:
Alex L. Yenkin, John C. Bramley, Colin L. Kremitzki, Jason E. Waligorski, Mariel J. Liebeskind, Xinyuan E. Xu, Vinay D. Chandrasekaran, Maria A. Vakaki, Graham W. Bachman, Robi D. Mitra, Jeffrey D. Milbrandt, William J. Buchser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Raft-Seq is a generalizable pooled screening platform that combines high-content imaging, machine learning and microraft isolation, and enables efficient screening of genetic perturbations based on their impact on phenotypes.
Externí odkaz:
https://doaj.org/article/63108157402f4421b5e89ea34d7f7eab
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The dual specificity phosphatase (DUSP) family has catalytically inactive members, called pseudophosphatases. They have mutations in their catalytic motifs that render them enzymatically inactive. This study analyzes the significance of two
Externí odkaz:
https://doaj.org/article/21dd595773304d9a949c441a781342b3
Autor:
Sarah E. Greene, Yuefang Huang, Wooseob Kim, Mariel J. Liebeskind, Vinay Chandrasekaran, Zhuoming Liu, Parakkal Deepak, Michael A. Paley, Daphne Lew, Monica Yang, Mehrdad Matloubian, Lianne S. Gensler, Mary C. Nakamura, Jane A. O'Hallaran, Rachel M. Presti, Sean P.J. Whelan, William J. Buchser, Alfred H.J. Kim, Gary J. Weil
Publikováno v:
Journal of Clinical Virology Plus, Vol 3, Iss 1, Pp 100135- (2023)
Objective: Lateral flow assays (LFA) are sensitive for detecting antibodies to SARS-CoV-2 proteins within weeks after infection. This study tested samples from immunocompetent adults, and those receiving treatments for chronic inflammatory diseases (
Externí odkaz:
https://doaj.org/article/b66e64cea7a54f1a8f541b5f7c3ad1eb
Autor:
Mark A Zaydman, Alexander S Little, Fidel Haro, Valeryia Aksianiuk, William J Buchser, Aaron DiAntonio, Jeffrey I Gordon, Jeffrey Milbrandt, Arjun S Raman
Publikováno v:
eLife, Vol 11 (2022)
Cellular behaviors emerge from layers of molecular interactions: proteins interact to form complexes, pathways, and phenotypes. We show that hierarchical networks of protein interactions can be defined from the statistical pattern of proteome variati
Externí odkaz:
https://doaj.org/article/b0777089e53f4af9bf100c53466b6c9d
Autor:
Michael T. Lotze, Herbert J. Zeh, Bennett Van Houten, Tao Wang, Per Basse, Donna Beer Stolz, Patricia Loughran, Antonio Romo de Vivar Chavez, William J. Buchser, Michael E. De Vera, Xiaoyan Liang
PDF file - 86K, Transmission electron microscopy (TEM), ATP Quantification, and XF Bioenergetic Assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655ab72ee445455b1bd485c0cb6637fb
https://doi.org/10.1158/0008-5472.22389383
https://doi.org/10.1158/0008-5472.22389383
Autor:
Michael T. Lotze, Herbert J. Zeh, Bennett Van Houten, Tao Wang, Per Basse, Donna Beer Stolz, Patricia Loughran, Antonio Romo de Vivar Chavez, William J. Buchser, Michael E. De Vera, Xiaoyan Liang
PDF file - 428K, Supplemental Figure 1. Administration of rIL-2 inhibits tumor growth in murine hepatic metastasis model in a dose dependent fashion. Supplemental Figure 2. HDIL-2 alone or combined with CQ significantly inhibits Panc02 tumor growth,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c28605a3f94675aafb72f1f0f041a2
https://doi.org/10.1158/0008-5472.22389386.v1
https://doi.org/10.1158/0008-5472.22389386.v1
PDF file - 1.2MB, 1) cell population discrimination and lysis, 2) CD4 T-cell C-MA, 3) ATG5 KO, 4) Prolonged survival, 5) Caspase and Granzyme inhibitors, 6) Bafilomycin and LAMP1, 7) Imaging starvation and HCQ, 8) TGF-beta, 9)NKG2D ligands, 10) KIR i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576e404b861e071e1fb12fd3721f1dd3
https://doi.org/10.1158/0008-5472.22393479
https://doi.org/10.1158/0008-5472.22393479
Autor:
Mark A Zaydman, Alexander S Little, Fidel Haro, Valeryia Aksianiuk, William J Buchser, Aaron DiAntonio, Jeffrey I Gordon, Jeffrey Milbrandt, Arjun S Raman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3cea017ad4c8ea58d80ca9209cdd402
https://doi.org/10.7554/elife.74104.sa2
https://doi.org/10.7554/elife.74104.sa2
Autor:
Marciela M. DeGrace, Elodie Ghedin, Matthew B. Frieman, Florian Krammer, Alba Grifoni, Arghavan Alisoltani, Galit Alter, Rama R. Amara, Ralph S. Baric, Dan H. Barouch, Jesse D. Bloom, Louis-Marie Bloyet, Gaston Bonenfant, Adrianus C. M. Boon, Eli A. Boritz, Debbie L. Bratt, Traci L. Bricker, Liliana Brown, William J. Buchser, Juan Manuel Carreño, Liel Cohen-Lavi, Tamarand L. Darling, Meredith E. Davis-Gardner, Bethany L. Dearlove, Han Di, Meike Dittmann, Nicole A. Doria-Rose, Daniel C. Douek, Christian Drosten, Venkata-Viswanadh Edara, Ali Ellebedy, Thomas P. Fabrizio, Guido Ferrari, Will M. Fischer, William C. Florence, Ron A. M. Fouchier, John Franks, Adolfo García-Sastre, Adam Godzik, Ana Silvia Gonzalez-Reiche, Aubree Gordon, Bart L. Haagmans, Peter J. Halfmann, David D. Ho, Michael R. Holbrook, Yaoxing Huang, Sarah L. James, Lukasz Jaroszewski, Trushar Jeevan, Robert M. Johnson, Terry C. Jones, Astha Joshi, Yoshihiro Kawaoka, Lisa Kercher, Marion P. G. Koopmans, Bette Korber, Eilay Koren, Richard A. Koup, Eric B. LeGresley, Jacob E. Lemieux, Mariel J. Liebeskind, Zhuoming Liu, Brandi Livingston, James P. Logue, Yang Luo, Adrian B. McDermott, Margaret J. McElrath, Victoria A. Meliopoulos, Vineet D. Menachery, David C. Montefiori, Barbara Mühlemann, Vincent J. Munster, Jenny E. Munt, Manoj S. Nair, Antonia Netzl, Anna M. Niewiadomska, Sijy O’Dell, Andrew Pekosz, Stanley Perlman, Marjorie C. Pontelli, Barry Rockx, Morgane Rolland, Paul W. Rothlauf, Sinai Sacharen, Richard H. Scheuermann, Stephen D. Schmidt, Michael Schotsaert, Stacey Schultz-Cherry, Robert A. Seder, Mayya Sedova, Alessandro Sette, Reed S. Shabman, Xiaoying Shen, Pei-Yong Shi, Maulik Shukla, Viviana Simon, Spencer Stumpf, Nancy J. Sullivan, Larissa B. Thackray, James Theiler, Paul G. Thomas, Sanja Trifkovic, Sina Türeli, Samuel A. Turner, Maria A. Vakaki, Harm van Bakel, Laura A. VanBlargan, Leah R. Vincent, Zachary S. Wallace, Li Wang, Maple Wang, Pengfei Wang, Wei Wang, Scott C. Weaver, Richard J. Webby, Carol D. Weiss, David E. Wentworth, Stuart M. Weston, Sean P. J. Whelan, Bradley M. Whitener, Samuel H. Wilks, Xuping Xie, Baoling Ying, Hyejin Yoon, Bin Zhou, Tomer Hertz, Derek J. Smith, Michael S. Diamond, Diane J. Post, Mehul S. Suthar
Publikováno v:
Nature
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants jeopardizes the protective antiviral immunity induced following infection or vaccination. To address the public health threat caused by the increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e896e07b5a30bbcb962870bf7aaa91b
https://www.repository.cam.ac.uk/handle/1810/335637
https://www.repository.cam.ac.uk/handle/1810/335637