Zobrazeno 1 - 10
of 19
pro vyhledávání: '"William J, Bradshaw"'
Autor:
Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0293548 (2024)
RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc recept
Externí odkaz:
https://doaj.org/article/a694cd69ff044329bed258122700d8e8
Autor:
Oliver M. Crook, Kelsey Lane Warmbrod, Greg Lipstein, Christine Chung, Christopher W. Bakerlee, T. Greg McKelvey, Shelly R. Holland, Jacob L. Swett, Kevin M. Esvelt, Ethan C. Alley, William J. Bradshaw
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Identifying the designers of engineered biological sequences would help promote biotechnological innovation while holding designers accountable. Here the authors present the winners of a 2020 data-science competition which improved on previous attemp
Externí odkaz:
https://doaj.org/article/0f3e4593fa454b63b132992866454ef3
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Contact tracing is critical to controlling COVID-19, but most protocols only “forward-trace” to notify people who were recently exposed. Using a stochastic branching-process model, the authors show that “bidirectional” tracing to identify inf
Externí odkaz:
https://doaj.org/article/57bacde72cf14549a38abb0105ac3148
Autor:
Oliver M. Crook, Kelsey Lane Warmbrod, Greg Lipstein, Christine Chung, Christopher W. Bakerlee, T. Greg McKelvey, Shelly R. Holland, Jacob L. Swett, Kevin M. Esvelt, Ethan C. Alley, William J. Bradshaw
The ability to identify the designer of engineered biological sequences -- termed genetic engineering attribution (GEA) -- would help ensure due credit for biotechnological innovation, while holding designers accountable to the communities they affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba23621ddfe3bdd38172acd86b34151a
http://arxiv.org/abs/2110.11242
http://arxiv.org/abs/2110.11242
Autor:
Nicholas J. Harmer, Andrea Kovacs-Simon, Séverine Péchiné, Claire Janoir, Jean François Bruxelle, William J. Bradshaw, K. Ravi Acharya, Stephen L. Michell
Publikováno v:
The Journal of Biological Chemistry
Clostridioides difficile is the primary cause of antibiotic-associated diarrhea and colitis, a healthcare-associated intestinal disease resulting in a significant fatality rate. Colonization of the gut is critical for C. difficile pathogenesis. The b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2885bea93269d03a730cd8bed928d693
http://europepmc.org/articles/PMC6816091
http://europepmc.org/articles/PMC6816091
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Contact tracing is critical to controlling COVID-19, but most protocols only “forward-trace” to notify people who were recently exposed. Using a stochastic branching-process model, we find that “bidirectional” tracing to identify infector ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3d994651a02910403685916c2c07f7
Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef66b4db506d79dc48208867abf78f3b
https://doi.org/10.1101/2020.08.21.261248
https://doi.org/10.1101/2020.08.21.261248
Publikováno v:
Proc Biol Sci
Proceedings of the Royal Society B: Biological Sciences
Proceedings of the Royal Society B: Biological Sciences
The evolution of the adaptive immune system has provided vertebrates with a uniquely sophisticated immune toolkit, enabling them to mount precise immune responses against a staggeringly diverse range of antigens. Like other vertebrates, teleost fishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f4b5deadf91406e12c9324bb4d17a2
https://hdl.handle.net/21.11116/0000-000B-30A8-1
https://hdl.handle.net/21.11116/0000-000B-30A8-1
Publikováno v:
Journal of Cell Communication and Signaling
The nosocomially acquired pathogen Clostridium difficile is the primary causative agent of antibiotic associated diarrhoea and causes tens of thousands of deaths globally each year. C. difficile presents a paracrystalline protein array on the surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d0f75d4b5dcd3a00f1f4cea5ca3156
https://doi.org/10.1007/s12079-017-0429-z
https://doi.org/10.1007/s12079-017-0429-z
The evolution of the adaptive immune system has provided vertebrates with a uniquely sophisticated immune toolkit, enabling them to mount precise immune responses against a staggeringly diverse range of antigens. Like other vertebrates, teleost fishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57bdeace4e15e4e06887da8f3306c79
https://doi.org/10.1101/752063
https://doi.org/10.1101/752063