Zobrazeno 1 - 6
of 6
pro vyhledávání: '"William Hutch Jackson"'
Autor:
Sudharsan Periyasamy-Thandavan, William Hutch Jackson, Elangovan Gopal, William D. Hill, John R. Barrett, Vadivel Ganapathy, Brian Erickson, Kapil N. Bhalla, Julia S. Samaddar, Lauren Raney, Patricia V. Schoenlein
Publikováno v:
Autophagy. 6:19-35
In recent studies, we and others showed that autophagy is critical to estrogen receptor positive (ER+) breast cancer cell survival and the development of antiestrogen resistance. Consequently, new approaches are warranted for targeting autophagy in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5e771239375673fabf1e12db10bd72
https://doi.org/10.4161/auto.6.1.10323
https://doi.org/10.4161/auto.6.1.10323
Autophagy facilitates the progression of ERα-positive breast cancer cells to antiestrogen resistance
Autor:
Patricia V. Schoenlein, John T. Barrett, William Hutch Jackson, Julia S. Samaddar, Sudharsan Periyasamy-Thandavan
Publikováno v:
Autophagy. 5:400-403
A major impediment to the successful treatment of estrogen receptor alpha (ERalpha)-positive breast cancer is the development of antiestrogen resistance. Tamoxifen, the most commonly used antiestrogen, exerts its pharmacological action by binding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae7d41fad3baed7c4c111ddc18ecbda
https://doi.org/10.4161/auto.5.3.7784
https://doi.org/10.4161/auto.5.3.7784
Autor:
Patricia V. Schoenlein, Muthusamy Thangaraju, April Eve Welborn, Adam D. Singer, Derek LeRoith, Mario B. Marrero, Suchreet Takhar, Michael R. Dohn, Sudharsan Periyasamy-Thandavan, William Hutch Jackson, Shuang Huang
Publikováno v:
Breast Cancer Research : BCR
Introduction In this pre-clinical in vitro study conducted in estrogen receptor positive (ER+) breast cancer cells, we have characterized the effects of insulin-like growth factor I (IGF-1) on the cytostatic and cytotoxic action of antiestrogen treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65acc3b78e205a83bbe23e1a49768d0c
https://pubmed.ncbi.nlm.nih.gov/22429491
https://pubmed.ncbi.nlm.nih.gov/22429491
Autor:
Patricia V. Schoenlein, Sudharsan Periyasamy-Thandavan, William Hutch Jackson, Suchreet Takhar, Shuang Huang
Publikováno v:
Cancer Research. 71:2-2
In an effort to understand the underlying mechanisms of inherent antiestrogen resistance in estrogen receptor positive (ER+) breast cancer cells, we have been studying the pro-survival role of insulin-like growth factor 1 (IGF-1) in protecting breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb222bf7c936064ed8047390e401699c
https://doi.org/10.1158/1538-7445.am2011-2
https://doi.org/10.1158/1538-7445.am2011-2
Autor:
William Hutch Jackson, Patricia V. Schoenlein, Darren D. Browning, Julia S. Samaddar, Sudharsan Periyasamy-Thandavan, Suchreet Takhar, Adam D. Singer
Publikováno v:
Cancer Research. 70:4845-4845
In recent studies, we have demonstrated that autophagy is essential for the survival of estrogen receptor positive (ER+) breast cancer cells during anti-estrogen therapy and facilitates the development of antiestrogen resistance. For these studies, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a71eff39d2e640fb55d3d74c6675e98
https://doi.org/10.1158/1538-7445.am10-4845
https://doi.org/10.1158/1538-7445.am10-4845
Autor:
Patricia V. Schoenlein, Adam D. Singer, Sudharsan Periyasamy-Thandavan, Suchreet Takhar, William D. Hill, Samuel Herberg, William Hutch Jackson, Shuang Huang
Publikováno v:
Cancer Research. 70:4846-4846
In recent studies, we and others showed that autophagy is one of the prosurvival mechanisms during anti-estrogen therapy that plays a significant role in the development of resistance. In this study, we sought to determine if autophagy plays a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f0e93f51ee884f0f0cb5d71afe2baff
https://doi.org/10.1158/1538-7445.am10-4846
https://doi.org/10.1158/1538-7445.am10-4846