Zobrazeno 1 - 10
of 30
pro vyhledávání: '"William Hancock-Cerutti"'
Autor:
James H.J. Bevan, Kevin Ardon Casco, Nicolas Contento, Aditi Gadre, William Hancock-Cerutti, Chloé Jammes, Valentina Sedlacek, Perry Sheffield
Publikováno v:
European Medical Journal, Pp 67-75 (2023)
Medical education is lagging behind advances in planetary health knowledge due to the considerable barriers to introducing new topics into medical curricula. This potentially leaves doctors of the future ill-equipped to deal with the health challenge
Externí odkaz:
https://doaj.org/article/29112c622ee64fc4b44ee1dff00e222f
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 1, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/2481a8a621424c7aa1981f9cda158032
Autor:
William Hancock-Cerutti, John S. Millar, Silvia Valentini, Jason Liu, Jeffrey T. Billheimer, Daniel J. Rader, Marina Cuchel
Publikováno v:
Molecules, Vol 26, Iss 22, p 6862 (2021)
High-density lipoprotein cholesterol (HDL-C) is thought to be atheroprotective yet some patients with elevated HDL-C levels develop cardiovascular disease, possibly due to the presence of dysfunctional HDL. We aimed to assess the metabolic fate of ci
Externí odkaz:
https://doaj.org/article/f66898c6d66140b4838705aadba64154
Autor:
Shujun Cai, Yumei Wu, Andrés Guillén-Samander, William Hancock-Cerutti, Jun Liu, Pietro De Camilli
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
VPS13 is a eukaryotic lipid transport protein localized at membrane contact sites. Previous studies suggested that it may transfer lipids between adjacent bilayers by a bridge-like mechanism. Direct evidence for this hypothesis from a full-length str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255ef4d3eff907a598cc2301f459432b
https://pubmed.ncbi.nlm.nih.gov/35858323
https://pubmed.ncbi.nlm.nih.gov/35858323
Autor:
William Hancock-Cerutti, Zheng Wu, Peng Xu, Narayana Yadavalli, Marianna Leonzino, Arun Kumar Tharkeshwar, Shawn M. Ferguson, Gerald S. Shadel, Pietro De Camilli
Publikováno v:
Journal of Cell Biology. 221
Mutations in VPS13C cause early-onset, autosomal recessive Parkinson's disease (PD). We have established that VPS13C encodes a lipid transfer protein localized to contact sites between the ER and late endosomes/lysosomes. In the current study, we dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d0559572c5794f704554b0fcf83a39
https://doi.org/10.1083/jcb.202106046
https://doi.org/10.1083/jcb.202106046
This protocol describes an assay to detect motor deficits in mice by testing how long they can stay on a rotating rod before falling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55fb090d760f6197a7f2e22bbec45445
https://doi.org/10.17504/protocols.io.b7p9rmr6
https://doi.org/10.17504/protocols.io.b7p9rmr6
This protocol describes the depletion of mitochondrial DNA (mtDNA) from HeLa cells using ethidium bromide (EtBr).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65c603e904c41bfaddce8ba4fb92636
https://doi.org/10.17504/protocols.io.b7qarmse
https://doi.org/10.17504/protocols.io.b7qarmse
This protocol describes the fixation of cultured cells in paraformaldehyde solution and immunofluorescent labeling of mitochondria and DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89ff201e13a1b05d33633b910e50d348
https://doi.org/10.17504/protocols.io.b7qbrmsn
https://doi.org/10.17504/protocols.io.b7qbrmsn
Autor:
William Hancock-Cerutti
This protocol describes an assay to detect motor deficits in mice by testing their ability to traverse a thin dowel between towers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb94e87fd934638befd43a7fb0915de5
https://doi.org/10.17504/protocols.io.bp2l618edvqe/v1
https://doi.org/10.17504/protocols.io.bp2l618edvqe/v1
This protocol describes the genetic modification of cultured cells using CRISPR-Cas9, including synthesis of reagents, transfection, selection and screening of single clones, and sequencing of genomic DNA to confirm mutations. In addition, this proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9e135e1d1b084095eddf155a58156b
https://doi.org/10.17504/protocols.io.b7p7rmrn
https://doi.org/10.17504/protocols.io.b7p7rmrn