Zobrazeno 1 - 10
of 125
pro vyhledávání: '"William Hancock"'
Autor:
James H.J. Bevan, Kevin Ardon Casco, Nicolas Contento, Aditi Gadre, William Hancock-Cerutti, Chloé Jammes, Valentina Sedlacek, Perry Sheffield
Publikováno v:
European Medical Journal, Pp 67-75 (2023)
Medical education is lagging behind advances in planetary health knowledge due to the considerable barriers to introducing new topics into medical curricula. This potentially leaves doctors of the future ill-equipped to deal with the health challenge
Externí odkaz:
https://doaj.org/article/29112c622ee64fc4b44ee1dff00e222f
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 1, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/2481a8a621424c7aa1981f9cda158032
Autor:
Ashok K. Goel, William Hancock
Publikováno v:
Design Science, Vol 7 (2021)
Much of the literature on biologically inspired design makes two, often unstated and largely unexamined, assumptions: (i) The process of biologically inspired design is independent of the biological domain, and (ii) the design process leads to multif
Externí odkaz:
https://doaj.org/article/4da9c47e75b54a18b287f2359bfea69b
Autor:
William Hancock-Cerutti, John S. Millar, Silvia Valentini, Jason Liu, Jeffrey T. Billheimer, Daniel J. Rader, Marina Cuchel
Publikováno v:
Molecules, Vol 26, Iss 22, p 6862 (2021)
High-density lipoprotein cholesterol (HDL-C) is thought to be atheroprotective yet some patients with elevated HDL-C levels develop cardiovascular disease, possibly due to the presence of dysfunctional HDL. We aimed to assess the metabolic fate of ci
Externí odkaz:
https://doaj.org/article/f66898c6d66140b4838705aadba64154
Autor:
Tomader Ali, George Kokotos, Victoria Magrioti, Robert N Bone, James A Mobley, William Hancock, Sasanka Ramanadham
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71748 (2013)
Ongoing studies suggest an important role for iPLA2β in a multitude of biological processes and it has been implicated in neurodegenerative, skeletal and vascular smooth muscle disorders, bone formation, and cardiac arrhythmias. Thus, identifying an
Externí odkaz:
https://doaj.org/article/98220f483b8445c79a9c1c4be28a5dcd
Autor:
William Hancock, Taylor Zaniewski
KIF1A is an essential neuronal transport motor protein in the kinesin-3 family, known for its superprocessive motility. We determined that superprocessivity of KIF1A dimers originates from a unique structural domain, the lysine rich insertion in loop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338752be8501dcf428eb418d29ef6292
https://doi.org/10.1101/2022.08.21.504701
https://doi.org/10.1101/2022.08.21.504701
Autor:
Shujun Cai, Yumei Wu, Andrés Guillén-Samander, William Hancock-Cerutti, Jun Liu, Pietro De Camilli
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
VPS13 is a eukaryotic lipid transport protein localized at membrane contact sites. Previous studies suggested that it may transfer lipids between adjacent bilayers by a bridge-like mechanism. Direct evidence for this hypothesis from a full-length str
Autor:
William Hancock-Cerutti, Zheng Wu, Peng Xu, Narayana Yadavalli, Marianna Leonzino, Arun Kumar Tharkeshwar, Shawn M. Ferguson, Gerald S. Shadel, Pietro De Camilli
Publikováno v:
Journal of Cell Biology. 221
Mutations in VPS13C cause early-onset, autosomal recessive Parkinson's disease (PD). We have established that VPS13C encodes a lipid transfer protein localized to contact sites between the ER and late endosomes/lysosomes. In the current study, we dem
This protocol describes an assay to detect motor deficits in mice by testing how long they can stay on a rotating rod before falling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55fb090d760f6197a7f2e22bbec45445
https://doi.org/10.17504/protocols.io.b7p9rmr6
https://doi.org/10.17504/protocols.io.b7p9rmr6
This protocol describes the depletion of mitochondrial DNA (mtDNA) from HeLa cells using ethidium bromide (EtBr).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65c603e904c41bfaddce8ba4fb92636
https://doi.org/10.17504/protocols.io.b7qarmse
https://doi.org/10.17504/protocols.io.b7qarmse