Zobrazeno 1 - 10
of 115
pro vyhledávání: '"William H. R. Langridge"'
Autor:
Dequina A. Nicholas, Jacques C. Mbongue, Darysbel Garcia-Pérez, Dane Sorensen, Heather Ferguson Bennit, Marino De Leon, William H. R. Langridge
Publikováno v:
Immuno, Vol 4, Iss 1, Pp 91-107 (2024)
Around 285 million people worldwide currently have type 2 diabetes and it is projected that this number will be surpassed by 2030. Therefore, it is of the utmost importance to enhance our comprehension of the disease’s development. The regulation o
Externí odkaz:
https://doaj.org/article/38fba84317d249d6bee16decbb9ae187
Publikováno v:
Immuno, Vol 3, Iss 2, Pp 217-227 (2023)
The 19th century saw the development of vaccines, which were biological preparations designed to enhance immunity against specific diseases. Edible vaccines function by stimulating both systemic and mucosal immune responses against foreign pathogens,
Externí odkaz:
https://doaj.org/article/5675089225204db1b6b5b52ff7abb41c
Autor:
Béla Dénes, Ryan N. Fuller, Wayne Kelin, Tessa R. Levin, Jaipuneet Gil, Aaren Harewood, Márta Lőrincz, Nathan R. Wall, Anthony F. Firek, William H. R. Langridge
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1865 (2023)
Mucosal vaccines protect against respiratory virus infection by stimulating the production of IgA antibodies that protect against virus invasion of the mucosal epithelium. In this study, a novel protein subunit mucosal vaccine was constructed for pro
Externí odkaz:
https://doaj.org/article/d396f221a67f4931b4751b7aa69e839f
Publikováno v:
Immuno, Vol 2, Iss 3, Pp 482-500 (2022)
Bacterial lipopolysaccharides (LPS), also referred to as endotoxins, are major outer surface membrane components present on almost all Gram-negative bacteria and are major determinants of sepsis-related clinical complications including septic shock.
Externí odkaz:
https://doaj.org/article/35082e60567e4c5cb4f9a0cacc23c442
Autor:
Dequina A. Nicholas, Lorena M. Salto, Kristen Lavelle, Joy Wilson, W. Lawrence Beeson, Anthony Firek, William H. R. Langridge, Zaida Cordero-MacIntyre, Marino De Leon
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Purpose. En Balance, a culturally sensitive diabetes education program, improves glycemic control in Hispanics with type 2 diabetes. The program emphasized diet, physical activity, and other factors important for glycemic control. However, the indivi
Externí odkaz:
https://doaj.org/article/0cbf37a6912440b2b09f2bfb59b34a56
Autor:
Dequina A. Nicholas, Lorena M. Salto, Ava M. Boston, Nan Sun Kim, Marco Larios, W. Lawrence Beeson, Anthony F. Firek, Carlos A. Casiano, William H. R. Langridge, Zaida Cordero-MacIntyre, Marino De Leon
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
High levels of serum long chain saturated fatty acids (LCSFAs) have been associated with inflammation in type 2 diabetes. Dietary SFAs can promote inflammation, the secretion of IgG antibodies, and secretion of the proinflammatory cytokine IL-1β. Th
Externí odkaz:
https://doaj.org/article/faa81a7faa394b338830525bc3cfc65b
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Data presented here demonstrate multifunctional vaccination strategies that harness vaccinia virus mediated delivery of a gene encoding an immunoenhanced diabetes autoantigen in combination with complete Freund’s adjuvant (CFA) that can maintain sa
Externí odkaz:
https://doaj.org/article/659d17b734844ad6afa17a224baae502
Autor:
Blake Babcock, John Morgan, Jukes P. Namm, William H. R. Langridge, David Shavlik, Maheswari Senthil, Matthew J. Selleck, Sharon S. Lum, Mark E. Reeves, Naveenraj L. Solomon, Liang Ji, Jane Xu, Nathan R. Wall, Carlos A. Garberoglio
Publikováno v:
Annals of Surgical Oncology. 27:240-247
Gastric cancer (GC) peritoneal carcinomatosis (PC) is associated with a poor prognosis. Although grade, histology, and stage are associated with PC, the cumulative risk of PC when multiple risk factors are present is unknown. This study aimed to deve
Publikováno v:
Cellular Immunology. 338:32-42
Autoantigen-specific immunotherapy promises effective treatment for devastating tissue specific autoimmune diseases like multiple sclerosis (MS) and type 1 diabetes (T1D). Because activated dendritic cells (DCs) stimulate the differentiation of autor
Publikováno v:
Molecular Immunology. 104:37-46
Vimentin is an intermediate filament protein traditionally considered to be an intracellular protein with a structural role. However, recent evidence suggests that vimentin can also be found outside the cell in disease conditions such as cancer, trau