Zobrazeno 1 - 10
of 38
pro vyhledávání: '"William H. Porter"'
Autor:
Darren M. Roberts, Robert S. Hoffman, Jeffrey Brent, Valéry Lavergne, Knut Erik Hovda, William H. Porter, Kenneth E. McMartin, Marc Ghannoum
Publikováno v:
Clinical Toxicology. 60:798-807
Ethylene glycol poisoning manifests as metabolic acidemia, acute kidney injury and death. The diagnosis and treatment depend on history and biochemical tests. Glycolate is a key toxic metabolite that impacts prognosis, but assay results are not widel
Autor:
William H. Porter
Publikováno v:
Clinica Chimica Acta. 413:365-377
Ethylene glycol poisoning is a medical emergency that presents challenges both for clinicians and clinical laboratories. Untreated, it may cause morbidly or death, but effective therapy is available, if administered timely. However, the diagnosis of
Publikováno v:
Clinica Chimica Acta. 411:601-604
Background There have been an increasing number of reports on false increase of lactate in ethylene glycol poisoning. We recently encountered two cases of ethylene glycol poisoning with very high blood lactate concentrations on ABL blood gas analyzer
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 39:607-615
To correlate serum glycolic acid levels with clinical severity and outcome in ethylene glycol poisoning and to determine if glycolic acid levels are predictive of renal failure and the need for hemodialysis.We measured serum ethylene glycol and glyco
Autor:
Philip W. Rutter, William H. Porter
Publikováno v:
Clinical Chemistry. 56:1900-1902
To the Editor: Our laboratory developed procedures for the simultaneous measurement of ethylene glycol and glycolic acid by gas chromatography–flame ionization detection (GC-FID)1 (1) and by GC-MS (2). The selection of a suitable structurally simil
Autor:
Robert Bruce, Richard Greenburg, Larry C. Munch, Richard S. Jerauld, Ardis D. Hoven, William H. Porter, Philip W. Rutter
Publikováno v:
Urology. 50:513-518
Objectives To report the association between the protease inhibitor indinavir and the development of urolithiasis. Methods Case reports of three adult patients infected with the human immunodeficiency virus who developed surgical renal stones while b
Autor:
William H. Porter, H H Yao
Publikováno v:
Clinical Chemistry. 42:292-297
We developed a gas-chromatographic procedure for the simultaneous determination of ethylene glycol (EG) and its major toxic metabolite, glycolic acid (GA), suitable for clinical use in instances of EG intoxication. After serum protein precipitation w
Autor:
Gary L. Fuller, Alex A. Pappas, Michael S. Monaghan, Bruce H. Ackerman, Keith M. Olsen, William H. Porter
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 33:141-149
The purpose of this investigation was to 1) compare the performance of proton nuclear magnetic resonance spectroscopy to gas chromatography head-space analysis in the measurement of serum isopropanol and its metabolite, acetone, obtained during a sim
Publikováno v:
Journal of Analytical Toxicology. 17:273-277
Proton nuclear magnetic resonance spectroscopy (1H MRS) has been used to identify ethanol in vivo and to detect other exogenous low molecular weight volatiles in human serum. 1H MRS was used to detect and quantitate 15 human sera containing various c
Autor:
William H. Porter
Publikováno v:
ChemInform. 22
Many drugs are administered as racemates, yet the enantiomers may have important pharmacodynamic and/or pharmacokinetic differences. Chiral analytical techniques are necessary to properly assess and understand such differences. Novel techniques to se