Zobrazeno 1 - 10
of 59
pro vyhledávání: '"William H. Miles"'
Autor:
Dasan M. Thamattoor, Cassidy M. Madison, Christopher Y. Kim, William H. Miles, Daniel J. Sweitzer, Shelby D. Valent
Publikováno v:
Journal of Organometallic Chemistry. 851:218-224
The synthesis of stemofurans C, L and T was achieved using organomanganese arene complexes. The critical carbon-carbon bond between the C-2 position of benzofuran and the arene was established in a regioselective manner directed by the cationic manga
Publikováno v:
Tetrahedron Letters. 57:3929-3932
The seven-step synthesis of the C3–C7 fragment from 3-furanmethanol is described. The key step is an asymmetric aldol reaction of a γ-hydroxybutenolide with the titanium enolate of an N -propionyloxazolidinone. The resulting lactone was reduced to
Autor:
Jason S. George, Natalie E. Jasiewicz, Daniel Beideman, Dasan M. Thamattoor, Stephanie M. Petersen, Samantha M. Zeiders, Ryan E. Cerbone, William H. Miles, Ida B. G. Suarsana, Joseph V. Leo, Nicholas J. Albano, Barbara J. Naimoli
Publikováno v:
Synthesis. 48:924-934
The Diels–Alder reaction of γ-hydroxybutenolides with dienes gave good yields of cycloadducts under thermal and Lewis acid catalyzed conditions. The application of this methodology to a more complex system was demonstrated by the synthesis of a mo
Publikováno v:
Tetrahedron Letters. 56:2303-2306
The synthesis of the all-syn C35–C39 stereopentad of etnangien has been achieved using the asymmetric aldol reaction of a γ-hydroxybutenolide (5-hydroxy-4-methylfuran-2(5H)-one) as the key step in the five-step synthesis. The reaction of the titan
Autor:
William H. Miles
Publikováno v:
Current Organic Synthesis. 11:244-267
Publikováno v:
Synthetic Communications. 43:1980-1991
The Diels–Alder reaction of β-acylacrylic acids with dienes gave good yields and good regio- or stereoselectivity of the corresponding cycloaddition products with the use of Lewis acids.
Publikováno v:
The Journal of organic chemistry. 81(22)
Several naphthalene compounds containing a methyl group in a 1,8-relationship to a metal-complexed phenyl ring bearing various substituents have been synthesized. The through-space shielding effects of the phenyl ring, as a function of substituent an
Autor:
Katelyn B. Connell, Elizabeth A. Dethoff, Varun Mehta, William H. Miles, April J Thrall, Gözde Ulas, Hannah H. Tuson
Publikováno v:
The Journal of Organic Chemistry. 75:6820-6829
The A-rings of calcitriol (1α,25-dihydroxyvitamin D(3)) and 1α-hydroxy-3-deoxyvitamin D(3) were synthesized using the furan approach. The critical steps in the synthesis of the A-ring of calcitriol involved an asymmetric carbonyl-ene reaction of 3-
Autor:
Elliot O. Goodzeit, Daniela Duca, William H. Miles, Chiquita A. Palha De Sousa, Brandon R. Selfridge, Jaryd T. Freedman, Kristin B. Hamman
Publikováno v:
Tetrahedron Letters. 48:7809-7812
The amine-catalyzed epimerization of chiral γ-hydroxybutenolides leads to a fast exchange on the NMR time scale.
Publikováno v:
Synthetic Communications. 34:1871-1880
Ytterbium, scandium, and lanthanum triflates catalyze the cleavage reactions of cyclic ethers to give various products. Most notable was the acylative cleavage of tetrahydrofuran with acetic anhydride catalyzed by Yb(triflate)3 to give the dimeric co