Zobrazeno 1 - 10
of 165
pro vyhledávání: '"William H. Jordan"'
Autor:
Deepa B. Rao, BVSc, M.S., Ph.D., David B. Hawver, Ph.D., David G. Hall, Ph.D., William H. Jordan, Ph.D.
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00418- (2024)
Externí odkaz:
https://doaj.org/article/7b05aae5a3ac4e6cb2d3eed434aedbae
Autor:
William H. Jordan
In January 1944, a US Army Air Corps transport, en route to its home base in India, crashed into a snowfield in Tibet, killing all crew members. Because of the remote location and fierce winter weather, the aircraft was covered by heavy snowfall. The
Autor:
Sarah L. Hale, Rogely W. Boyce, Lydia Andrews-Jones, Robert C. Switzer, Bernard S. Jortner, Georg Krinke, Robert H. Garman, Peter B. Little, Mark T. Butt, John T. Boyce, William H. Jordan, Karl F. Jensen
Publikováno v:
Toxicologic Pathology. 39:52-57
This session at the 2010 joint symposium of the Society of Toxicologic Pathology (STP) and the International Federation of Societies of Toxicologic Pathologists (IFSTP) explored modern neuropathology methods for assessing the neurotoxicologic potenti
Publikováno v:
Toxicologic Pathology. 39:58-65
For many pathologists, neuropathology is intimidating. Practical approaches for nervous tissue histologic evaluations to meet both routine and advanced study designs can lead to rewarding neuropathology efforts. Cost-effective, high-quality histologi
Autor:
Alok K. Sharma, Paul W. Snyder, William H. Jordan, Rachel Y. Reams, Timothy P. Ryan, Alan Y. Chiang, George H. Searfoss, Robert A. Jolly
Publikováno v:
Toxicologic Pathology. 37:776-789
Mesial temporal lobe epilepsy (MTLE) is a severe neurological condition of unknown pathogenesis for which several animal models have been developed. To obtain a better understanding of the underlying molecular mechanisms and identify potential biomar
Publikováno v:
Toxicologic Pathology. 36:932-943
Since there is limited information in the literature, the purpose of this study was to investigate clinical signs, morphology, and temporal progression of lesions from Days 3 to 168 in a kainic acid (KA)-induced Fischer-344 (F-344) rat model of mesia
Publikováno v:
Journal of Histotechnology. 30:115-120
The nervous system is composed of many anatomically and functionally interrelated parts, which tend to be sensitive to artifacts. Although specific design details for neuropathological evaluations in rats will be driven by the goals of a specific stu
Autor:
Donna D. Brown, David M. Holtzman, Laura I. Boone, Matthew T. Bryan, Bruce D. Gitter, Kelly R. Bales, Steven M. Paul, Maia Parsadainian, Wherly P. Hoffman, Daniel K. Ness, Kathy S. Piroozi, William H. Jordan, Deena L. Hepburn, Patrick J. C. May, Margaret M. Racke, Ronald Demattos
Publikováno v:
The Journal of Neuroscience. 25:629-636
Passive immunization with an antibody directed against the N terminus of amyloid beta (Abeta) has recently been reported to exacerbate cerebral amyloid angiopathy (CAA)-related microhemorrhage in a transgenic animal model. Although the mechanism resp
Publikováno v:
American Journal of Gastroenterology. 111:1376-1377
Autor:
David O. Calligaro, Marnie A. Higgins, Linda M. Schirtzinger, Timothy P. Ryan, Hong Gao, Elizabeth Galbreath, George H. Searfoss, Patrick C. May, Brian R. Berridge, William H. Jordan
Publikováno v:
Journal of Biological Chemistry. 278:46107-46116
Functional gamma-secretase inhibitors (FGSIs) can block the cleavage of several transmembrane proteins including amyloid precursor protein (APP), and the cell fate regulator Notch-1. FGSIs, by inhibiting APP processing, block the generation of amyloi