Zobrazeno 1 - 10
of 11
pro vyhledávání: '"William H. Holleman"'
Autor:
Todd W. Rockway, Yoichi Fujiwara, T. W. von Geldern, Thomas J. Perun, Tooru Kimura, Kenichi Akaji, Yoshiaki Kiso, William H. Holleman
Publikováno v:
Peptide Chemistry 1992 ISBN: 9789401046480
Peptide Chemistry 1992
Peptide Chemistry 1992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::281fcbeb12ef47c183c9864aca329173
https://doi.org/10.1007/978-94-011-1474-5_128
https://doi.org/10.1007/978-94-011-1474-5_128
Autor:
Todd W. Rockway, Thomas W. von Geldern, Alexander M. Buko, William H. Holleman, Carol A. Marselle, Terry J. Opgenorth, Steven K. Davidsen, Steven P. Cepa, Edward M. Devine
Publikováno v:
International journal of peptide and protein research. 40(6)
The degradation of a prototypical small analogue of atrial natriuretic peptide (ANP) has been studied using HPLC and mass spectrometric techniques. These studies revealed that removal of the N-terminal amino acid was the primary catabolic event in vi
Autor:
M Y Chu-Moyer, E N Bush, William H. Holleman, Scott D. Lucas, Steven K. Davidsen, Todd W. Rockway, M C Johnson, T. W. von Geldern, G. P. Budzik, E. M. Devine
Publikováno v:
Journal of medicinal chemistry. 35(5)
Structure/activity studies on atrial natriuretic peptide ANP (1-28) have highlighted three portions of the native molecule as necessary for its biological responses. We have linked these three regions and excised the remaining segments to produce a f
Autor:
William H. Holleman, T. W. von Geldern, T. J. Opgenorth, A. M. Thomas, G. P. Budzik, E. M. Devine, D. M. Pollock, Todd W. Rockway
Publikováno v:
Canadian journal of physiology and pharmacology. 69(10)
The synthesis, receptor binding, and agonist activity of a series of truncated atrial natriuretic analogs (ANF) are described. These analogs incorporate two portions of the native 28 amino peptide, the eight amino acids C-terminal to Cys7, and two am
Autor:
E. D. Devine, Todd W. Rockway, Steven K. Davidsen, P. J. Connolly, G. P. Budzik, Scott D. Lucas, E N Bush, T. W. von Geldern, William H. Holleman
Publikováno v:
Peptides ISBN: 9789401090629
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfaeb7bb84aaa4b3b99426cf256f19d
https://doi.org/10.1007/978-94-010-9060-5_81
https://doi.org/10.1007/978-94-010-9060-5_81
Publikováno v:
Biochemical and Biophysical Research Communications. 131:517-523
Using a variety of two-dimensional NMR methods, the 1 H NMR resonances of rat ANF(1–23) in dimethyl sulfoxide-d6 solution have been assigned. Two-dimensional phase sensitive correlated spectroscopy was used to identify protons that are scalar coupl
Publikováno v:
Thrombosis Research. 23:79-90
The adhesion of rabbit gel filtered platelets (GFP) to collagen-Sepharose includes both energy dependent and independent phases. The energy dependent phase was evident by the partial reduction of platelet adhesion to immobilized collagen in the prese
Autor:
Edward M. Devine, Todd W. Rockway, Susan L. Firestone, E N Bush, G. P. Budzik, Virender K. Sarin, William H. Holleman
Publikováno v:
Drug Development Research. 12:109-117
The atrial natriuretic factor (ANF) family of peptides possesses diverse functional properties including smooth-muscle relaxation, inhibition of aldosterone biosynthesis, and hypotensive activities. These separate activities are most likely mediated
Publikováno v:
Thrombosis research. 13(4)
We analyzed the anticoagulant activity of heparins in human plasma and in sheep plasma upon recalcification using the technique of clot elasticity measurement. Heparins with different molecular weight (M.W.) distributions, fractionated by Ultrogel Ac
Autor:
G. P. Budzik, Peter J. Connolly, Susan L. Firestone, Virender K. Sarin, Todd W. Rockway, Eugene N. Bush, William H. Holleman
Publikováno v:
Biochemical and biophysical research communications. 144(1)
ANF analog potencies in stimulating smooth muscle cell cGMP were compared with the ability to relax histamine-constricted rabbit aorta in vitro. ANF[1-28], [5-28], [5-27] and Lys-11[5-28] elevated cGMP and were potent vasorelaxants. ANF[7-23] and Lys