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pro vyhledávání: '"William H. Gendron"'
Autor:
Emre Fertan, William H. Gendron, Aimée A. Wong, Gabrielle M. Hanson, Richard E. Brown, Ian C. G. Weaver
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Reduced insulin-like growth factor 2 (IGF2) levels in Alzheimer’s disease (AD) may be the mechanism relating age-related metabolic disorders to dementia. Since Igf2 is an imprinted gene, we examined age and sex differences in the relations
Externí odkaz:
https://doaj.org/article/63573e24d4b14e2ba9b4a7f1e2c0f3ff
Autor:
William H. Gendron, Younes Anini, Emre Fertan, Stephanie Pelletier, Kyle M. Roddick, Timothy P. O'Leary, Richard E. Brown
Publikováno v:
Behavioural Brain Research. 406:113214
In addition to cognitive decline, patients with Alzheimer's disease (AD) exhibit sensory, motor, and neuropsychiatric deficits. Many AD patients also show weight loss, suggesting that AD may involve a metabolic syndrome. The 5xFAD mouse model shows a