Zobrazeno 1 - 10
of 106
pro vyhledávání: '"William H. Chambers"'
Autor:
Oliver M. Sieber, Patricia Gorman, Simon J. Leedham, Elinor J. Sawyer, Andrew Rowan, Ian Tomlinson, Anita C. Jones, Stefania Segditsas, Enric Domingo, Nicholas A. Wright, Rebecca Roylance, William H. Chambers, Kimberley Howarth
The seminal 'two-hit hypothesis' implicitly assumes that bi-allelic tumour suppressor gene (TSG) mutations cause loss of protein function. All subsequent events in that tumour therefore take place on an essentially null background for that TSG protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa670cd9a33eee16ed002fab65897dd
https://ora.ox.ac.uk/objects/uuid:f78b4257-d913-459b-bcf3-5867b907c243
https://ora.ox.ac.uk/objects/uuid:f78b4257-d913-459b-bcf3-5867b907c243
Autor:
Britteny Episcopo, Andrew Baum, Melanie S. Flint, William H. Chambers, Kelly Z. Knickelbein, Angela Liegey Dougall, Frank J. Jenkins
Publikováno v:
Stress. 16:114-121
Epinephrine and norepinephrine are produced during psychological stress and can directly bind to cells to induce DNA damage. These effects may have more long-lasting consequences such as DNA mutations resulting in an increased potential for cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aded027d57e49533a78671851ae9be
https://doi.org/10.3109/10253890.2012.686075
https://doi.org/10.3109/10253890.2012.686075
Autor:
Raghvendra S. Sengar, Norma Arbujas, Erik C. Wiener, William H. Chambers, Laima Spokauskiene, Daniel P. Steed, Patricia Griffin
Publikováno v:
Magnetic Resonance in Medicine. 62:599-606
Dendritic cells (DCs) are the most effective antigen-presenting cells (APCs) and are used in a variety of immunotherapeutic approaches. Adoptive cellular immunotherapy (ACI) of cancer using DCs has attracted much interest due to their capacity to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9c624c15dc3e470797b89784d62e117
https://doi.org/10.1002/mrm.22030
https://doi.org/10.1002/mrm.22030
Autor:
Valeria P. Makarenkova, William H. Chambers, Ronald B. Herberman, William E. Gooding, Tjendimin Tjandrawan, Shen Li, Jun Xu, Theresa L. Whiteside, Jukka Vakkila, Torsten E. Reichert, Carl F. Lagenaur, Nikola L. Vujanovic, Cristian L. Achim
Publikováno v:
Journal of Leukocyte Biology. 76:1187-1199
Activated, adherent natural killer (A-NK) cells represent a distinct subpopulation of interleukin (IL)-2-stimulated NK cells, which are selectively endowed with the increased expression of integrins and ability to adhere to solid surfaces, migrate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ce133b167fa421106214a6d09b9f0e
https://doi.org/10.1189/jlb.0802386
https://doi.org/10.1189/jlb.0802386
Autor:
William H. Chambers, Katinka M. Giezeman-Smits, Douglas M. Potter, T. F. Whitham, J. C. Kettel, Cynthia S. Brissette-Storkus, Lorissa Villa
Publikováno v:
Journal of Leukocyte Biology. 71:941-949
Bone marrow-derived dendritic cells (DC) of the rat have not been as well characterized as those from the mouse. Here, large quantities of bone marrow-derived rat DC were generated when Flt-3 ligand (FL) was used as an adjunct to granulocyte macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c87c36e888ecae1082279d563e4e3996
https://doi.org/10.1189/jlb.71.6.941
https://doi.org/10.1189/jlb.71.6.941
Publikováno v:
Neurosurgery. 50:1327-1335
OBJECTIVE: On the basis of recent studies indicating that tumoral apoptotic bodies may provide a potent source of antigen for delivery to antigen-presenting cells, as well as observations that signal transduction modulation may constitute a promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3541520da01f852d97cd2e5abd87b3ee
https://doi.org/10.1227/00006123-200206000-00025
https://doi.org/10.1227/00006123-200206000-00025
Autor:
Wendy Fellows, William H. Chambers, Lorissa Villa, Melanie Erff, Michael T. Lotze, Ian F. Pollack, Hideho Okada, Jason Attanucci
Publikováno v:
Gene Therapy. 8:1157-1166
To provide a means for comparing strategies for cytokine gene therapy against intracranial (i.c.) tumors, we generated rat gliosarcoma 9L cells transfected with interleukin-4 (9L-IL4), interleukin-12 (9L-IL12), granulocyte-macrophage colony-stimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697e3cafa6ede977cfae0c31d1e93523
https://doi.org/10.1038/sj.gt.3301496
https://doi.org/10.1038/sj.gt.3301496
Autor:
Douglas M. Potter, David Schiff, Frank S. Lieberman, Douglas Kondziolka, Jason Attanucci, Hideho Okada, Elaine M. Elder, Howard Edington, Lunsford Ld, Pawel Kalinski, William H. Chambers, Ian F. Pollack, D. Kinzler, Theresa L. Whiteside
Publikováno v:
Human Gene Therapy. 12:575-595
IND 8918 Principal Investigator: Hideho Okada, M.D., Ph.D. Co-investigators: Ian F. Pollack, M.D. Frank Lieberman, M.D. Associate Investigators: Neurological Surgery L. Dade Lunsford, M.D. Douglas Kondziolka, M.D. David Schiff, M.D. Jason Attanucci,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95f4f640cfecd07ec5b7bbc1585808
https://doi.org/10.1089/104303401300042528
https://doi.org/10.1089/104303401300042528
Publikováno v:
International Reviews of Immunology. 20:439-502
While it is generally accepted that natural killer (NK) cells, by killing tumor cells in the circulation, represent a first line of defense against metastases, their therapeutic activity against established tumors has been limited. In this review, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b4b33afcea32e54e711e6a7ac463ef
https://doi.org/10.3109/08830180109054416
https://doi.org/10.3109/08830180109054416