Zobrazeno 1 - 10
of 572
pro vyhledávání: '"William H Robinson"'
Autor:
Vivian P Bykerk, Anne R Bass, Karmela K Chan, Susan Goodman, Nilasha Ghosh, William H Robinson, Amit Lakhanpal, Pankti Reid, Carlos Andres Aude, Jessica Kirschman, Diviya Rajesh
Publikováno v:
RMD Open, Vol 9, Iss 2 (2023)
Background Immune checkpoint inhibitors (ICI) can potentially cause ICI-inflammatory arthritis (ICI-IA), which often resembles rheumatoid arthritis (RA). In this study, we examined the degree of anticitrullinated peptide antibodies (ACPA) epitope exp
Externí odkaz:
https://doaj.org/article/f2d0f0537a4d4813bf32852857e80d48
Autor:
Jan M Hughes-Austin, Ronit Katz, Darcy S Majka, Michael H Criqui, William H Robinson, Gary S Firestein, W Gregory Hundley, Joachim H Ix
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0291967 (2023)
BackgroundAntibodies to citrullinated protein antigens have been linked to altered left ventricular (LV) structure and function in patients with rheumatoid arthritis (RA). Serum reactivity to several citrullinated protein/peptide antigens has been id
Externí odkaz:
https://doaj.org/article/775a2e0975764ace8e44e85ac2229d98
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Here, we offer a roadmap for what might be studied next in understanding how EBV triggers MS. We focus on two areas: The first area concerns the molecular mechanisms underlying how clonal antibody in the CSF emanates in widespread molecular
Externí odkaz:
https://doaj.org/article/78ed79c9f8d147ca865e0009cc6a9861
Autor:
Jason Ptacek, Rachael E Hawtin, Dongmei Sun, Brent Louie, Erik Evensen, Barbara B Mittleman, Alessandra Cesano, Guy Cavet, Clifton O Bingham, Stacey S Cofield, Jeffrey R Curtis, Maria I Danila, Chander Raman, Richard A Furie, Mark C Genovese, William H Robinson, Marc C Levesque, Larry W Moreland, Peter A Nigrovic, Nancy A Shadick, James R O'Dell, Geoffrey M Thiele, E William St Clair, Christopher C Striebich, Matthew B Hale, Houman Khalili, Franak Batliwalla, Cynthia Aranow, Meggan Mackay, Betty Diamond, Garry P Nolan, Peter K Gregersen, S Louis Bridges
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244187 (2021)
Rheumatoid arthritis (RA) is a systemic and incurable autoimmune disease characterized by chronic inflammation in synovial lining of joints. To identify the signaling pathways involved in RA, its disease activity, and treatment response, we adapted a
Externí odkaz:
https://doaj.org/article/9b1ea73e854343108c3cc3ca29f2e25a
Autor:
Qian Wang, Christin M Lepus, Harini Raghu, Laurent L Reber, Mindy M Tsai, Heidi H Wong, Ericka von Kaeppler, Nithya Lingampalli, Michelle S Bloom, Nick Hu, Eileen E Elliott, Francesca Oliviero, Leonardo Punzi, Nicholas J Giori, Stuart B Goodman, Constance R Chu, Jeremy Sokolove, Yoshihiro Fukuoka, Lawrence B Schwartz, Stephen J Galli, William H Robinson
Publikováno v:
eLife, Vol 8 (2019)
Osteoarthritis is characterized by articular cartilage breakdown, and emerging evidence suggests that dysregulated innate immunity is likely involved. Here, we performed proteomic, transcriptomic, and electron microscopic analyses to demonstrate that
Externí odkaz:
https://doaj.org/article/a7082ff767514c069f8232e435419a7c
Autor:
Jan M Hughes-Austin, Kevin D Deane, Jon T Giles, Lezlie A Derber, Gary O Zerbe, Dana M Dabelea, Jeremy Sokolove, William H Robinson, V Michael Holers, Jill M Norris
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199578 (2018)
BACKGROUND:Extra-articular manifestations of rheumatoid arthritis (RA), potentially due to systemic inflammation, include cardiovascular disease and sarcopenic obesity. Adiponectin, an adipose-derived cytokine, has been implicated in inflammatory pro
Externí odkaz:
https://doaj.org/article/87e7099770f944baa76c2df5cbf6a792
Autor:
Laurent L Reber, Philipp Starkl, Bianca Balbino, Riccardo Sibilano, Nicolas Gaudenzio, Stephan Rogalla, Steven Sensarn, Dongmin Kang, Harini Raghu, Jeremy Sokolove, William H Robinson, Christopher H Contag, Mindy Tsai, Stephen J Galli
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185704 (2017)
Gouty arthritis is caused by the deposition of monosodium urate (MSU) crystals in joints. Despite many treatment options for gout, there is a substantial need for alternative treatments for patients unresponsive to current therapies. Tyrosine kinase
Externí odkaz:
https://doaj.org/article/1798954157d444b6b3e1ed39d91cf0ae
Autor:
Jong-Hyuk Kim, Eva Furrow, Michelle G Ritt, Paul J Utz, William H Robinson, Liping Yu, Andrea Eckert, Kathleen Stuebner, Timothy D O'Brien, Lawrence Steinman, Jaime F Modiano
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152397 (2016)
Diabetes mellitus occurs spontaneously in dogs. Although canine diabetes shares many features with human type-1 diabetes, there are differences that have cast doubt on the immunologic origin of the canine disease. In this study, we examined whether p
Externí odkaz:
https://doaj.org/article/f558ffdd9f254a4f93bb56af705d68b0
Autor:
Wolfgang Hueber, William H Robinson
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol 2009, Iss default, Pp 39-48 (2009)
Wolfgang Hueber1,2,3, William H Robinson1,21VA Palo Alto Health Care System, Palo Alto, CA, USA; 2Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA; 3Novartis Institutes of Biomedical Research, Novarti
Externí odkaz:
https://doaj.org/article/00a1885436e0479ea1e785f10236a34c
Autor:
Mark J Soloski, Lauren A Crowder, Lauren J Lahey, Catriona A Wagner, William H Robinson, John N Aucott
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93243 (2014)
Chemokines and cytokines are key signaling molecules that orchestrate the trafficking of immune cells, direct them to sites of tissue injury and inflammation and modulate their states of activation and effector cell function. We have measured, using
Externí odkaz:
https://doaj.org/article/306aa939c5c34dc1b203d69c8135e313