Zobrazeno 1 - 10
of 115
pro vyhledávání: '"William H R, Langridge"'
Autor:
Dequina A. Nicholas, Jacques C. Mbongue, Darysbel Garcia-Pérez, Dane Sorensen, Heather Ferguson Bennit, Marino De Leon, William H. R. Langridge
Publikováno v:
Immuno, Vol 4, Iss 1, Pp 91-107 (2024)
Around 285 million people worldwide currently have type 2 diabetes and it is projected that this number will be surpassed by 2030. Therefore, it is of the utmost importance to enhance our comprehension of the disease’s development. The regulation o
Externí odkaz:
https://doaj.org/article/38fba84317d249d6bee16decbb9ae187
Publikováno v:
Immuno, Vol 3, Iss 2, Pp 217-227 (2023)
The 19th century saw the development of vaccines, which were biological preparations designed to enhance immunity against specific diseases. Edible vaccines function by stimulating both systemic and mucosal immune responses against foreign pathogens,
Externí odkaz:
https://doaj.org/article/5675089225204db1b6b5b52ff7abb41c
Publikováno v:
Immuno, Vol 2, Iss 3, Pp 482-500 (2022)
Bacterial lipopolysaccharides (LPS), also referred to as endotoxins, are major outer surface membrane components present on almost all Gram-negative bacteria and are major determinants of sepsis-related clinical complications including septic shock.
Externí odkaz:
https://doaj.org/article/35082e60567e4c5cb4f9a0cacc23c442
Autor:
Béla Dénes, Ryan N. Fuller, Wayne Kelin, Tessa R. Levin, Jaipuneet Gil, Aaren Harewood, Márta Lőrincz, Nathan R. Wall, Anthony F. Firek, William H. R. Langridge
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1865 (2023)
Mucosal vaccines protect against respiratory virus infection by stimulating the production of IgA antibodies that protect against virus invasion of the mucosal epithelium. In this study, a novel protein subunit mucosal vaccine was constructed for pro
Externí odkaz:
https://doaj.org/article/d396f221a67f4931b4751b7aa69e839f
Autor:
Dequina A. Nicholas, Lorena M. Salto, Kristen Lavelle, Joy Wilson, W. Lawrence Beeson, Anthony Firek, William H. R. Langridge, Zaida Cordero-MacIntyre, Marino De Leon
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Purpose. En Balance, a culturally sensitive diabetes education program, improves glycemic control in Hispanics with type 2 diabetes. The program emphasized diet, physical activity, and other factors important for glycemic control. However, the indivi
Externí odkaz:
https://doaj.org/article/0cbf37a6912440b2b09f2bfb59b34a56
Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β.
Autor:
Dequina A Nicholas, Kangling Zhang, Christopher Hung, Shane Glasgow, Aruni Wilson Aruni, Juli Unternaehrer, Kimberly J Payne, William H R Langridge, Marino De Leon
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176793 (2017)
Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknow
Externí odkaz:
https://doaj.org/article/f4f7cabda7da4fb6ac03a7ce1cbd7027
Autor:
Nan-Sun Kim, Jacques C Mbongue, Dequina A Nicholas, Grace E Esebanmen, Juli J Unternaehrer, Anthony F Firek, William H R Langridge
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147509 (2016)
A chimeric protein vaccine composed of the cholera toxin B subunit fused to proinsulin (CTB-INS) was shown to suppress type 1 diabetes onset in NOD mice and upregulate biosynthesis of the tryptophan catabolic enzyme indoleamine 2, 3-dioxygenase (IDO1
Externí odkaz:
https://doaj.org/article/ef6a1bb7a8324ebfaa37b98734ab72e7
Autor:
Jacques C Mbongue, Dequina A Nicholas, Kangling Zhang, Nan-Sun Kim, Brittany N Hamilton, Marco Larios, Guangyu Zhang, Kazuo Umezawa, Anthony F Firek, William H R Langridge
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118562 (2015)
Dendritic cells (DC) interact with naïve T cells to regulate the delicate balance between immunity and tolerance required to maintain immunological homeostasis. In this study, immature human dendritic cells (iDC) were inoculated with a chimeric fusi
Externí odkaz:
https://doaj.org/article/bfd8079b8ab3400d823e6395638e5f63
Autor:
Dequina A. Nicholas, Lorena M. Salto, Ava M. Boston, Nan Sun Kim, Marco Larios, W. Lawrence Beeson, Anthony F. Firek, Carlos A. Casiano, William H. R. Langridge, Zaida Cordero-MacIntyre, Marino De Leon
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
High levels of serum long chain saturated fatty acids (LCSFAs) have been associated with inflammation in type 2 diabetes. Dietary SFAs can promote inflammation, the secretion of IgG antibodies, and secretion of the proinflammatory cytokine IL-1β. Th
Externí odkaz:
https://doaj.org/article/faa81a7faa394b338830525bc3cfc65b
Autor:
Blake Babcock, John Morgan, Jukes P. Namm, William H. R. Langridge, David Shavlik, Maheswari Senthil, Matthew J. Selleck, Sharon S. Lum, Mark E. Reeves, Naveenraj L. Solomon, Liang Ji, Jane Xu, Nathan R. Wall, Carlos A. Garberoglio
Publikováno v:
Annals of Surgical Oncology. 27:240-247
Gastric cancer (GC) peritoneal carcinomatosis (PC) is associated with a poor prognosis. Although grade, histology, and stage are associated with PC, the cumulative risk of PC when multiple risk factors are present is unknown. This study aimed to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53622839dc55f0ca765ecb7e0bc7e2b
https://doi.org/10.1245/s10434-019-07624-0
https://doi.org/10.1245/s10434-019-07624-0