Zobrazeno 1 - 10
of 184
pro vyhledávání: '"William H, Peranteau"'
Autor:
Dominique L. Brooks, Manuel J. Carrasco, Ping Qu, William H. Peranteau, Rebecca C. Ahrens-Nicklas, Kiran Musunuru, Mohamad-Gabriel Alameh, Xiao Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Phenylketonuria (PKU), an autosomal recessive disorder caused by pathogenic variants in the phenylalanine hydroxylase (PAH) gene, results in the accumulation of blood phenylalanine (Phe) to neurotoxic levels. Current dietary and medical trea
Externí odkaz:
https://doaj.org/article/a955591fbb65411b9f8d9923910aa8ee
Autor:
Sourav K. Bose, Brandon M. White, Meghana V. Kashyap, Apeksha Dave, Felix R. De Bie, Haiying Li, Kshitiz Singh, Pallavi Menon, Tiankun Wang, Shiva Teerdhala, Vishal Swaminathan, Heather A. Hartman, Sowmya Jayachandran, Prashant Chandrasekaran, Kiran Musunuru, Rajan Jain, David B. Frank, Philip Zoltick, William H. Peranteau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Lysosomal storage diseases like mucopolysaccharidosis type I (MPS I) cause pathology before birth and result in early morbidity and mortality. Here, the authors show that in utero base editing mediates multi-organ phenotypic and survival benefits in
Externí odkaz:
https://doaj.org/article/a932a6ec2ba7497281b8dba976e50d99
Autor:
Heron D. Baumgarten, Christina M. Wright, Avery C. Rossidis, Kendall M. Lawrence, Aimee G. Kim, Ali Y. Mejaddam, Patrick E. McGovern, Melissa N. Orr, Barbara E. Coons, Zoya Butt, Haiying Li, Grace Hwang, Antoneta Radu, Lauren J. Brown, Ronald C. Rubenstein, William H. Peranteau, Marcus Davey, Robert O. Heuckeroth, Alan W. Flake
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 623-637 (2020)
Background and Aims: The Extra-Uterine Environment for Neonatal Development (EXTEND) aims to avoid the complications of prematurity, such as NEC. Our goal was to determine if bowel development occurs normally in EXTEND-supported lambs, with specific
Externí odkaz:
https://doaj.org/article/3769f4f865ec4e579017f0679c426f4e
Publikováno v:
Current Opinion in Obstetrics & Gynecology. 35:134-139
Autor:
Apeksha Dave, Cara L. Berkowitz, Valerie L. Luks, Brandon M. White, Rohan Palanki, Marco D. Carpenter, John S. Riley, Sourav K. Bose, Haiying Li, Li Li, Pallavi V. Menon, Shiva Teerdhala, Mina Ebrahimi, Philip W. Zoltick, William H. Peranteau
Publikováno v:
Gene Therapy. 30:232-235
Publikováno v:
American Journal of Surgical Pathology. 47:568-579
Publikováno v:
Clinics in Perinatology. 49:811-820
Significant advances in maternal-fetal medicine and gene sequencing technology have fostered a new frontier of in utero molecular and cellular therapeutics, including gene editing, enzyme replacement therapy, and stem cell transplantation to treat si
Autor:
Nya D. Nelson, Feng Xu, Prashant Chandrasekaran, Leslie A. Litzky, William H. Peranteau, David B. Frank, Marilyn Li, Jennifer Pogoriler
Publikováno v:
Modern Pathology. 35:1870-1881
The potential pathogenetic mechanisms underlying the varied morphology of congenital pulmonary airway malformations (CPAMs) have not been molecularly determined, but a subset have been shown to contain clusters of mucinous cells (MCC). These clusters
Autor:
Josue Baeza, Barbara E. Coons, Zongtao Lin, John Riley, Mariel Mendoza, William H. Peranteau, Benjamin A Garcia
Publikováno v:
bioRxiv
Protein translational control is highly regulated step in the gene expression program during mammalian development that is critical for ensuring that the fetus develops correctly and that all of the necessary organs and tissues are formed and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ed7ebce8d1396ce115b3b504054cd1
https://doi.org/10.1101/2023.05.18.541242
https://doi.org/10.1101/2023.05.18.541242
Autor:
Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland, Jiancheng Han, Alexander J. Schupper, James T. Connelly, Kevin C. Dysart, Jack Rychik, Holly L. Hedrick, William H. Peranteau, Alan W. Flake
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The ability to support the development of a premature fetus in the form of an extracorporeal system has had limited success. Here, the authors show that an extra-uterine device that mimics the intra-uterine environment can provide physiologic support
Externí odkaz:
https://doaj.org/article/45db932763ce4371b11c234c5b821457